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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:37 PM IST
Neurokem MNT Tablet is a combination medicine used to manage diabetic neuropathy, neuropathic pain, and nutritional deficiencies. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like nausea, vomiting, diarrhoea, stomach upset, dizziness, and rash.
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Prescription drug

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Prescription drug
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Consult Doctor

Manufacturer/Marketer

Alkem Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-26

for this medicine

About Neurokem MNT Tablet

Neurokem MNT Tablet is a combination medicine indicated to manage neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, and evoked pain (pain caused by events usually not painful).

Neurokem MNT Tablet is a combination of three drugs: Methylcobalamin (vitamin), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Methylcobalamin is a vitamin that aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Neurokem MNT Tablet helps to treat neuropathic pain.

Take Neurokem MNT Tablet as prescribed. Based on your medical condition, your doctor will decide the dose and duration. In some cases, Neurokem MNT Tablet may cause dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of the lower legs and hands), weight gain, and dry mouth. The majority of these side effects do not necessitate medical attention and will subside gradually over time. However, if you are experiencing these side effects regularly, you should consult your doctor.

Please do not take Neurokem MNT Tablet if you are allergic to any of its ingredients. Consult your doctor before taking Neurokem MNT Tablet if you are pregnant or breastfeeding. Neurokem MNT Tablet may cause drowsiness and dizziness, so drive only if you are alert. Neurokem MNT Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Neurokem MNT Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Neurokem MNT Tablet

Treatment of Neuropathic pain

Medicinal Benefits

Neurokem MNT Tablet is a combination of three drugs: Methylcobalamin (a form of vitamin B), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Neurokem MNT Tablet is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Neurokem MNT Tablet helps to treat neuropathic pain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Neurokem MNT Tablet

  • Constipation
  • Dry mouth
  • Headache
  • Feeling sleepy, tired or dizzy
  • Diarrhoea

Drug Warnings

If you are allergic to any of the ingredients in Neurokem MNT Tablet , do not consume it. Please do not stop taking Neurokem MNT Tablet without first consulting your doctor, as this may result in withdrawal symptoms. If you are pregnant or breastfeeding, do not take Neurokem MNT Tablet unless your doctor has prescribed it. Neurokem MNT Tablet may cause drowsiness and dizziness, therefore drive only if you are alert. Neurokem MNT Tablet is not recommended for children as safety and effectiveness have not been established. Avoid drinking alcohol while taking Neurokem MNT Tablet as it may cause drowsiness and sleepiness. If you have suicidal thoughts, consult your doctor right away.

Drug Interactions

Drug-Drug Interactions: Neurokem MNT Tablet may have interaction with antidepressant medications (e.g. duloxetine, sertraline, escitalopram), pain killer medications (e.g. codeine, hydrocodone, morphine, oxycodone, tramadol, acetaminophen), anti-convulsant medications (e.g. topiramate), anti-anxiety medications (e.g. alprazolam), sedative-hypnotics medications (e.g. zolpidem), antihistamine medications (e.g. diphenhydramine, cetirizine), muscle relaxant medications (e.g. cyclobenzaprine), antiemetic medications (e.g. ondansetron), and herbal medications to treat depression (e.g. St John's wort).

Drug-Food Interactions: Avoid alcohol consumption while taking Neurokem MNT Tablet as it might cause increased drowsiness and sleepiness.

Drug-Disease Interactions: Use Neurokem MNT Tablet with medical advice if you have had anticholinergic effects, cardiovascular disease, pheochromocytoma, acute myocardial infarction recovery, cardiovascular disease, depression, seizure disorders, drug dependence, suicidal tendency, angioedema, creatine kinase elevations, peripheral oedema, PR interval prolongation, bone marrow suppression, diabetes, renal/liver disease, schizophrenia/bipolar disorder, hyper/hypoglycemia, schizophrenia, thyroid disorders and urinary retention.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • CODEINE
  • HYDROCODONE
  • MORPHINE
  • OXYCODONE
  • TRAMADOL
  • ACETAMINOPHEN
  • TOPIRAMATE
  • ALPRAZOLAM
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CYCLOBENZAPRINE
  • ONDANSETRON
  • ST JOHN'S WORT

Habit Forming

No

Diet & Lifestyle Advise

  • Include vitamin B and D-rich foods in your diet.

  • Cayenne pepper should be included in your diet because it can help with neuropathic pain.

  • Exercising regularly helps to improve overall health and combat pain.

  • Rest well and get plenty of rest.

  • Taking a warm bath can be very relaxing.

  • Avoid smoking and drinking alcohol.

  • Meditation and yoga can reduce stress, pain sensitivity and improve coping skills.

  • Acupuncture, by stimulating pressure points, can be beneficial.

  • Massages with essential oils can help increase circulation.

Special Advise

Neurokem MNT Tablet contains Nortriptyline (antidepressant), which can lead to suicidal thoughts. Suicidal thoughts or behaviour should be closely monitored in people taking Neurokem MNT Tablet . If you have suicidal thoughts, don't be afraid to talk to your doctor right away.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also familiar with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury. The body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Neurokem MNT Tablet as it may increase drowsiness and sleepiness.

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Pregnancy

Caution

If you're pregnant, don't take Neurokem MNT Tablet unless your doctor tells you to. Please consult your doctor if you have any concerns about this; your doctor will only prescribe if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on the use of Neurokem MNT Tablet in breastfeeding/nursing mothers.

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Driving

Unsafe

Neurokem MNT Tablet causes drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Neurokem MNT Tablet should not be given to children as the safety and efficacy have not been established.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - NEU1344

Author Details

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FAQs

Neurokem MNT Tablet is used to treat neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia.
Neurokem MNT Tablet contains Methylcobalamin, Nortriptyline, and Pregabalin. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline alters the way nerves receive pain signals, thereby decreasing pain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Neurokem MNT Tablet helps to treat neuropathic pain.
Dry mouth could be a side-effect of Neurokem MNT Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Do not stop taking Neurokem MNT Tablet without consulting your doctor, as this could result in withdrawal symptoms. Continue taking Neurokem MNT Tablet for as long as prescribed to treat your condition effectively. If you experience any difficulty while taking Neurokem MNT Tablet , do not be afraid to speak with your doctor.
Neurokem MNT Tablet is used to treat diabetic neuropathy. Diabetic neuropathy is a condition that causes nerve damage due to high blood glucose levels. It primarily affects the nerves in the legs and feet.
Neurokem MNT Tablet may cause peripheral oedema. The swelling of the hands and lower legs are known as peripheral oedema. If you experience oedema, avoid sitting or standing for extended periods. Raise your legs by laying down and placing a pillow under them.

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