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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 5:55 AM IST

Miragron ER 25 Tablet is used to treat overactive bladder. It contains Mirabegron,, which relaxes the muscles of the urinary bladder and decreases its activity. In some cases, this medicine may cause side effects such as nausea, constipation, diarrhoea, headache, dizziness, and increased heart rate. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Prescription drug

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Composition

MIRABEGRON-25MG

Manufacturer/Marketer

Steris Healthcare

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Miragron ER 25 Tablet

Miragron ER 25 Tablet belongs to the group of medications called ‘urinary antagonists' or 'antispasmodics' primarily used to treat overactive bladder (OAB) symptoms. Overactive bladder is a condition in which the urinary bladder muscles constrict uncontrollably, thereby causing an urgent need to urinate, frequent urination, and an inability to control urination.

Miragron ER 25 Tablet contains ‘mirabegron’ that relaxes the urinary bladder muscles, which in turn decreases the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder, causing the patient to have frequent urges to urinate. Miragron ER 25 Tablet stops these sudden contractions of urinary bladder muscles, thereby enabling control over urination. Thus, it increases the amount and volume of urine that can be held by the bladder.

In some cases, Miragron ER 25 Tablet may cause common side effects of Miragron ER 25 Tablet , which are nausea, constipation, diarrhoea, headache, dizziness, and increased heart rate. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult a doctor.

Do not take Miragron ER 25 Tablet if you are allergic to any of its ingredients. Before taking Miragron ER 25 Tablet , inform your doctor if you have kidney disease, liver disease, hypertension, urinary retention, angioedema, or a history of heart rhythm problems (including QT prolongation). Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating heavy machinery, as this medicine may cause dizziness.

Uses of Miragron ER 25 Tablet

Miragron ER 25 Tablet is used to treat Overactive bladder (urinary incontinence).

Medicinal Benefits

Miragron ER 25 Tablet contains 'mirabegron', which belongs to the class of medications called 'anticholinergics'. It can decrease the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder, causing the patient to have frequent urges to urinate. Miragron ER 25 Tablet can stop these sudden contractions of bladder muscles. It enables control over urination and increases the amount of urine held by your bladder.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not chew, crush or break it. Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.Granules for suspension: Check the label for directions and use it as advised by the doctor. Tap the bottle to loosen the granules and add 100ml of water. Shake vigorously for a minute and let it stand for 10-30 minutes. Shake again until the granules have dispersed. Take the prescribed dose as advised by the doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Miragron ER 25 Tablet

  • Nausea
  • Constipation
  • Diarrhoea
  • Headache
  • Dizziness
  • Increased heart rate

Drug Warnings

Do not take Miragron ER 25 Tablet if you are allergic to any ingredients present in it. Before taking Miragron ER 25 Tablet , inform your doctor if you have kidney disease, liver disease, hypertension, urinary retention, angioedema, or a history of heart rhythm problems (including QT prolongation). Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating heavy machinery, as this medicine may cause dizziness.

Drug Interactions

Drug-Drug Interactions: Miragron ER 25 Tablet may interact with other antifungal drugs (ketoconazole and itraconazole), antihypertensives (carvedilol, metoprolol), antacid (brexpiprazole), anti-psychotic (pimozide, thioridazine),  anti-allergic (chlorpheniramine), anti-tussive (dextromethorphan), blood thinners (warfarin, coumadin), anti-depressants (desipramine), anti-arrhythmic (digoxin, flecainide, propafenone), drugs used to treat overactive bladder (darifenacin, fesoterodine, oxybutynin, tolterodine, trospium).

Drug-Food Interactions: Do not take grapefruit or grapefruit juice while using Miragron ER 25 Tablet .

Drug-Disease Interactions: Miragron ER 25 Tablet should be used with caution in patients with urinary retention (inability to urinate), heart rhythm problems (including QT prolongation), hypertension, kidney dialysis, severe liver disease, or severe kidney disease.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • CARVEDILOL
  • METOPROLOL
  • PIMOZIDE
  • THIORIDAZINE
  • CHLORPHENIRAMINE
  • DEXTROMETHORPHAN
  • WARFARIN
  • COUMADIN
  • DESIPRAMINE
  • DIGOXIN
  • FLECAINIDE
  • PROPAFENONE
  • DARIFENACIN
  • FESOTERODINE
  • OXYBUTYNIN
  • TOLTERODINE
  • TROSPIUM

Habit Forming

No

Diet & Lifestyle Advise

  • Eat fresh fruits like pears, bananas, citrus fruits, and vegetables like beans and potatoes.
  • Try to take cranberry juice as it helps in minimizing urinary infections.
  • Avoid coffee, tea, and carbonated drinks which contain caffeine.
  • Do not consume processed, fried, or spicy foods, as these can irritate your bladder.
  • Limit alcohol intake as it can increase the risk of side effects.
  • Quit smoking and exercise regularly.

Special Advise

  • Miragron ER 25 Tablet may raise your blood pressure. Monitor your blood pressure regularly.

Disease/Condition Glossary

Overactive bladder (OAB): In normal conditions, when the urinary bladder is filled with urine, it sends a message to the brain that an individual is ready to urinate. During the urination process, bladder muscles contract, which ultimately leads to a uniform flow of urine. Contrary to this, in an overactive bladder (OAB), the urinary bladder muscles start contracting before the urine is filled in the urinary bladder, thereby causing frequent urges to urinate.

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Alcohol

Caution

Avoid taking alcohol as it increases the risk of side effects.

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Pregnancy

Caution

Miragron ER 25 Tablet is not recommended for use in pregnant women unless absolutely necessary. Before taking this medicine, the risks and benefits should be discussed with the doctor.

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Breast Feeding

Caution

Miragron ER 25 Tablet is not recommended for use in breastfeeding women unless absolutely necessary. Before taking this medicine, the risks and benefits should be discussed with the doctor. If this medicine is used, close monitoring of the infant for undesired side effects is recommended.

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Driving

Caution

The use of this medicine may cause blurred vision or dizziness in some patients. You are advised not to perform any activities, such as driving a vehicle or operating machinery, if you experience any of these symptoms during treatment with this medicine.

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Liver

Caution

Miragron ER 25 Tablet should be used with caution in patients with severe liver disease. A dose adjustment of Miragron ER 25 Tablet may be needed. Please consult your doctor. Miragron ER 25 Tablet is not recommended for use in patients with severe liver disease.

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Kidney

Caution

Miragron ER 25 Tablet should be used with caution in patients with kidney disease. A dose adjustment of Miragron ER 25 Tablet may be needed. Please consult your doctor.

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Children

Caution

Miragron ER 25 Tablet should not be used in children below 12 years of age unless prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Tanaji Chowk, Mumbai
Other Info - MIR0204

Author Details

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FAQs

Miragron ER 25 Tablet belongs to the group of medications called ‘urinary antagonists' or 'antispasmodics' primarily used in the treatment of overactive bladder (OAB) symptoms.
Miragron ER 25 Tablet prevents sudden bladder muscle contractions and increases the volume and amount of urine the bladder can hold. Thus, Miragron ER 25 Tablet helps to control the release of urine and helps reduce symptoms of OAB like a strong urge to urinate, frequent urination and reduced urine flow.
If you have kidney disease, liver disease, hypertension, urinary retention, angioedema, history of heart rhythm problems (including QT prolongation), please contact a doctor before taking Miragron ER 25 Tablet .
Ketoconazole is an antifungal medicine, and it may interact with Miragron ER 25 Tablet . So, inform your doctor about all the prescription and non-prescription medicines before taking Miragron ER 25 Tablet to avoid unwanted effects.
Miragron ER 25 Tablet should be used with caution in patients with high blood pressure due to the increased risk of worsening the patient's condition. It is not recommended for use in patients with severe uncontrolled hypertension. Regular blood pressure monitoring, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Miragron ER 25 Tablet may cause side effects such as nausea, headache, diarrhoea, constipation, increased heart rate and dizziness. If these side effects persist or worsen, please consult your doctor.
No, Miragron ER 25 Tablet is not recommended for children as the safety and effectiveness were not established.
No, Miragron ER 25 Tablet is not known to cause an addiction. However, it should be taken in the dose and for duration as prescribed by your doctor.
Miragron ER 25 Tablet should be taken for as long as it is advised by the doctor. Follow all the instructions and do not discontinue taking Miragron ER 25 Tablet on your own.
It might take 8 weeks or more for Miragron ER 25 Tablet to show its full benefits. After 4 to 8 weeks, the dosage might be increased based on how well the medicine suits and affects the patient.
No, do not stop taking Miragron ER 25 Tablet even if you start feeling better as it does not cure overactive bladder but relieves the symptoms of urgency, frequency and incontinence (unable to control when you empty your bladder). Discontinuing Miragron ER 25 Tablet may result in a recurrence of the overactive bladder symptoms.
No, Miragron ER 25 Tablet does not affect sleep. However, if you have any sleep related problems, consult your doctor.
No, you are recommended to take Miragron ER 25 Tablet daily as advised by your doctor as it controls your condition and does not cure it. Since your bladder takes time to adapt to the medicine, if you take it off and on, you will not get the desired benefits and your symptoms will recur.
Miragron ER 25 Tablet may cause side effects such as infection of kidneys, urinary bladder, ureters, or urethra but does not affect everyone. Miragron ER 25 Tablet has been associated with very few reports of developing bladder pain and kidney stones. Also, patients with compromised kidney function should be careful while using Miragron ER 25 Tablet and in case of any unwanted symptoms related to kidneys, inform your doctor.
If you accidentally take more than the required dose of Miragron ER 25 Tablet , seek medical help immediately even if you do not feel any discomfort. Overdose of Miragron ER 25 Tablet may increase your blood pressure and pulse rate resulting in severe headache, chest pain, palpitations and fatigue.

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