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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 13, 2024 | 11:26 AM IST
Metsilo Tablet is used to treat liver disease. It effectively prevents multiple liver disease mechanisms and ensures the protection, regeneration, and rejuvenation of the liver. In some cases, this medicine may cause side effects such as headache, fatigue, diarrhoea, abdominal pain, and nausea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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About Metsilo Tablet

Metsilo Tablet is a combination medicine used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Liver diseases lead to disturbance of vital liver functions. Metsilo Tablet effectively prevents multiple liver disease mechanisms and ensures protection, regeneration, and rejuvenation of the liver. 

Metsilo Tablet contains Metadoxine, Silymarin, L-ornithine-L-aspartate, Folic acid, and Pyridoxine. Metadoxine restores the balance of saturated and unsaturated fatty acids in the liver by increasing the desaturase enzyme. It accelerates the metabolism of the liver, restores ATP synthesis and redox balance of hepatocytes. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps in the production of new liver cells. L-ornithine-L-aspartate rejuvenates the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, Metsilo Tablet helps in treating liver disease.

You are advised to take Metsilo Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, fatigue, diarrhoea, abdominal pain, and nausea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Let your doctor know if you are allergic to any of the contents. Consult your doctor before taking Metsilo Tablet if you are pregnant or breastfeeding. Avoid consuming alcohol with Metsilo Tablet as it could lead to further liver damage. Metsilo Tablet should not be given to children unless prescribed by the doctor. Keep your doctor informed if you are taking any other prescription/non-prescription medications, including herbal products and supplements.

Uses of Metsilo Tablet

Treatment of Liver disease

Medicinal Benefits

Metsilo Tablet is a combination of five drugs: Metadoxine, Silymarin, L-ornithine-L-aspartate, Folic acid, and Pyridoxine. Metsilo Tablet is used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Metadoxine restores the balance of saturated and unsaturated fatty acids in the liver by increasing the desaturase enzyme. It accelerates the metabolism of the liver and the redox balance of hepatocytes. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps produce new liver cells. L-ornithine and L-aspartate rejuvenate the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, Metsilo Tablet helps in treating liver disease. A single drug does not prevent multiple mechanisms involved; hence, Metsilo Tablet effectively prevents multiple liver disease mechanisms and ensures protection, regeneration, and rejuvenation of the liver. 

Directions for Use

Swallow Metsilo Tablet a whole with a glass of water; do not chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Metsilo Tablet

  • Headache
  • Fatigue
  • Nausea
  • Diarrhoea
  • Abdominal pain

Drug Warnings

Do not take Metsilo Tablet if you are allergic to any of its components. Consult your doctor before taking Metsilo Tablet if you are pregnant or breastfeeding. Avoid consuming alcohol as it could lead to further liver damage. Metsilo Tablet should not be given to children unless prescribed by the doctor. Inform your doctor regarding your health condition and the medicines you are taking to rule out any side-effects/interactions.  

Drug Interactions

Drug-Drug Interactions: Metsilo Tablet may interact with an anti-Parkinson agent (levodopa).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: No interactions found/established.

Drug-Drug Interactions Checker List

  • LEVODOPA

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid alcohol consumption and quit smoking. 
  • Maintain a healthy weight by exercising regularly.
  • Adopt a liver-friendly diet such as fibre-rich food.
  • Cut down on fats, sugar, and salt.
  • Avoid stress by practising yoga or meditation. 
  • Exercise regularly as it helps in reducing the accumulation of fat.

Special Advise

During the treatment with Metsilo Tablet , try to have a monthly liver function test (LFT). 

Disease/Condition Glossary

Liver disease: The liver is an important organ responsible for carrying out many vital functions such as metabolism, detoxification of waste, and energy storage. Liver diseases occur due to disturbance of liver functions. Liver diseases include acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Hepatitis occurs due to viral infection leading to liver damage and inflammation, making it difficult for the liver to function properly. The fatty liver could occur due to excess alcohol consumption (alcoholic fatty liver) or other factors (non-alcoholic fatty liver). Liver cirrhosis is damage to the liver, which causes scarring and liver failure. Jaundice occurs due to the build-up of bilirubin in the blood, which causes the yellowing of skin and eyes. Symptoms include dark urine, yellowing of skin and eyes, loss of appetite, fatigue, bloody or dark stools, nausea, and vomiting. 

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Alcohol

Unsafe

Avoid consumption of alcohol as it may lead to further liver damage.

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Pregnancy

Caution

Limited information is available regarding the usage of Metsilo Tablet in pregnancy. Consult your doctor before taking Metsilo Tablet if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited information is available regarding the usage of Metsilo Tablet in breastfeeding mothers. Consult your doctor before taking Metsilo Tablet ; your doctor will decide whether Metsilo Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

It is not known if Metsilo Tablet interferes with your ability to drive. Be cautious while driving or operating machinery.

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Liver

Safe if prescribed

Metsilo Tablet is used to treat various liver diseases. So, it is probably safe to be taken by patients with liver impairment. However, consult your doctor if you have any concerns.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Metsilo Tablet in patients with kidney impairment.

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Children

Caution

Limited information is available regarding the usage of Metsilo Tablet in children. Please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

208, 2Nd Floor Gupta Tower-1, G-Block, Vikas Puri, New Delhi-18
Other Info - MET2473

Author Details

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FAQs

Metsilo Tablet is used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease).
Metsilo Tablet contains Metadoxine, Silymarin, L-ornithine, L-aspartate, Folic acid, and Pyridoxine. Metadoxine restores the balance of saturated and unsaturated fatty acids in the liver by increasing the desaturase enzyme. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps in the production of new liver cells. L-ornithine-L-aspartate rejuvenates the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, Metsilo Tablet helps in treating liver disease.
To treat your condition effectually, continue taking Metsilo Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Metsilo Tablet .
Please consult your doctor before taking levodopa with Metsilo Tablet as it might lower the efficacy of levodopa.
Diarrhoea could be a side-effect of Metsilo Tablet . Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in stools.
Metsilo Tablet effectively prevents multiple liver disease mechanisms and ensures protection, regeneration, and rejuvenation of the liver. Thereby, treats liver disease and helps in the proper functioning of the liver.
Metsilo Tablet may cause indigestion, but taking it with or after a meal can help prevent indigestion. If indigestion continues, consult your doctor.
Store Metsilo Tablet in a cool, dry, and dark place. Protect from light. Keep it out of reach of children.
Metsilo Tablet causes side effects such as headache, nausea, diarrhoea, and abdominal pain. However, these side effects are temporary and do not require any medical attention, as they will gradually reduce over time. Please, contact a doctor if these persist for longer durations.

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