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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Methofast 15 Injection 3 ml belongs to the class of antimetabolite medications used in the treatment of polyarticular juvenile rheumatoid arthritis, psoriasis, breast cancer, cervical cancer, bladder cancer, ovarian cancer, testicular cancer, lung cancer, head and neck cancer, bone cancer, and advanced stage non-Hodgkin's lymphomas. This medicine works by interfering with the immune system process that causes inflammation and prevents the growth of cancer-causing cells.
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Composition :

METHOTREXATE-15MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Methofast 15 Injection 3 ml

Methofast 15 Injection 3 ml belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis and severe psoriasis. Methofast 15 Injection 3 ml is also used to treat cancer such as breast cancer, cervical cancer, bladder cancer, ovarian cancer, testicular cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), bone cancer, and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system).

Methofast 15 Injection 3 ml contains 'Methotrexate' that works by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Besides this, Methofast 15 Injection 3 ml prevents and stops the growth of cancer cells, thereby helps treat cancer. Methofast 15 Injection 3 ml treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis.

Methofast 15 Injection 3 ml will be administered by a qualified healthcare professional; do not self-administer. In some cases, Methofast 15 Injection 3 ml may cause side-effects such as nausea, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, tingling sensation, leukopenia (decreased number of white blood cells), and soreness of mouth and lips. You are advised to talk to your doctor if you experience any of the side effects persistently.

Do not take Methofast 15 Injection 3 ml if you are pregnant or breastfeeding. Methofast 15 Injection 3 ml may cause dizziness and fatigue, so avoid driving or operating machinery. Avoid consuming alcohol whilst on treatment with Methofast 15 Injection 3 ml. If you are due to undergo any surgery, including dental surgery, inform the doctor that you are receiving Methofast 15 Injection 3 ml. Do not have any vaccinations during treatment with Methofast 15 Injection 3 ml without consulting your doctor. Inform your doctor about your medications and health condition to rule out any unpleasant side effects.

Uses of Methofast 15 Injection 3 ml

Treatment of Rheumatoid arthritis, Psoriasis and Cancer

Medicinal Benefits

Methofast 15 Injection 3 ml belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis including polyarticular juvenile rheumatoid arthritis (arthritis in children) and severe psoriasis. Methofast 15 Injection 3 ml helps treat rheumatoid arthritis by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Methofast 15 Injection 3 ml treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis. Methofast 15 Injection 3 ml is used to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system). Methofast 15 Injection 3 ml prevents and stops the growth of cancer cells by interfering with DNA production.

Side Effects of Methofast 15 Injection 3 ml

  • Nausea
  • Vomiting
  • Diarrhoea
  • Unusual fatigue
  • Dizziness
  • Headache
  • Loss of appetite
  • Elevated liver enzymes
  • Lowered resistance to infections
  • Tingling sensation
  • Leukopenia (decreased number of white blood cells)
  • Soreness of mouth and lips

Directions for Use

Methofast 15 Injection 3 ml will be administered by a qualified healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Methofast 15 Injection 3 ml if you are allergic to any of its contents; if you are pregnant or breastfeeding. Inform your doctor if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, liver, lung or kidney problems, ulceration in the stomach or bowels, poor general condition, received any vaccinations or if are due to have any, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs. Methofast 15 Injection 3 ml may cause a serious, life-threatening reaction. If you experience symptoms such as rash, itching, hives, throat tightness, trouble swallowing, swelling of the face, throat, lips, or tongue; runny or stuffy nose, lightheadedness or dizziness, chest pain, difficulty breathing, wheezing, or feeling faint, consult your doctor immediately. Inform your doctor if you are undergoing radiation therapy; if you receive Methofast 15 Injection 3 ml while you are being treated with radiation therapy for cancer, it may cause damage to the skin, bones, or other parts of the body.

Therapeutic Class

ANTIMETABOLITES

Drug-Drug Interactions

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MethotrexateEtretinate
Critical
MethotrexateAspirin
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

Arthritis:

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help reduce inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Psoriasis:

  • Include foods such as cherries, berries, leafy vegetables, salmon, sardines, and fish rich in omega-3 fatty acids.
  • Consume antioxidant-rich spices and herbs like cumin, ginger, sage and thyme.
  • Avoid processed foods, refined sugars, and fatty foods.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a good sleep cycle would be helpful.
  • Avoiding getting in contact with harsh soaps, detergents and rough fabrics.

Cancer:

  • Consume a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

What if I have taken an overdose of Methofast 15 Injection 3 ml

Methofast 15 Injection 3 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include vomiting, diarrhoea and gastrointestinal bleeding, as well as severe bone marrow suppression and disturbance of liver function. Your doctor may take necessary measures if an overdose is suspected.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Methofast 15 Injection 3 ml.

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Pregnancy

Unsafe

Methofast 15 Injection 3 ml may cause serious birth defects. It is not recommended to take Methofast 15 Injection 3 ml while you are pregnant.

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Breast Feeding

Unsafe

Methofast 15 Injection 3 ml passes into breast milk. Avoid breastfeeding whilst on treatment with Methofast 15 Injection 3 ml and for at least 1 week after the last dose.

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Driving

Caution

Methofast 15 Injection 3 ml may cause dizziness and tiredness; do not drive or operate heavy machinery until you know how Methofast 15 Injection 3 ml affects you.

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Liver

Caution

Please consult your doctor if you have liver impairment before taking Methofast 15 Injection 3 ml.

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Methofast 15 Injection 3 ml.

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Children

Caution

The efficacy and safety of Methofast 15 Injection 3 ml in children have been established in polyarticular-course juvenile rheumatoid arthritis and cancer chemotherapy. Please consult your doctor if you have any concerns regarding the usage of Methofast 15 Injection 3 ml in children.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - MET1885

Author Details

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FAQs

Methofast 15 Injection 3 ml acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby providing relief from rheumatoid arthritis.
Methofast 15 Injection 3 ml works by suppressing the overactive immune system that is responsible for causing psoriasis. Methofast 15 Injection 3 ml interferes with the synthesis of genetic material (DNA) and the growth of cells that multiply faster than usual, thereby helping in treating psoriasis.
Methofast 15 Injection 3 ml may affect fertility in men and women. Consult your doctor if you have any concerns regarding this.
Methofast 15 Injection 3 ml causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Methofast 15 Injection 3 ml may make your skin sensitive to sunlight. Therefore, avoid prolonged or unnecessary exposure to sunlight or ultraviolet light such as tanning beds and sunlamps. Wear protective clothing, sunglasses, and sunscreen while going out.

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