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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Melanocyl Solution is used to treat Psoriasis (scaly, itchy, and red patches on the skin) and vitiligo (discoloured patches in different body areas, including the skin and hair). It contains methoxsalen, which is used alongside ultraviolet-A radiation. It works by reducing the number of cells the skin makes. If you are pregnant or planning pregnancy or nursing mother, please inform your doctor. Your doctor will prescribe only if the benefits outweigh the risks.
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Consume Type

TOPICAL

Return Policy

Not Returnable

Expires on or after

Jan-27

About Melanocyl Solution

Melanocyl Solution belongs to the class of drugs called psoralens (light-sensitive drugs) used along with controlled ultraviolet light in a treatment called psoralen plus ultraviolet light A (PUVA) to treat skin conditions such as vitiligo and psoriasis. Psoriasis is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. Vitiligo is a skin condition that causes loss of skin colour in blotches when melanocytes (cells that produce the colour) do not produce skin pigment, melanin (that gives the skin colour). 

Melanocyl Solution contains methoxsalen, which is used alongside ultraviolet-A radiation. It works by reducing the number of cells the skin makes.

Melanocyl Solution is for external use only. Some people may experience itching or skin irritation. Most of these side effects of Melanocyl Solution do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Methoxsalen or any other medicines, please inform your doctor. If you are pregnant or a nursing mother, it is advised to inform your doctor before using Melanocyl Solution. After UVA exposure, you are recommended to wash the treated area of the skin with soap and water. Then use sunscreen or wear protective clothing to protect the treated area. If you have squamous cell cancer (a form of skin cancer) or melanoma (a serious type of skin cancer), please inform your doctor beforehand.

Uses of Melanocyl Solution

Treatment of Psoriasis (scaly, itchy, and red patches on the skin), and vitiligo (discoloured patches in different areas of the body, including the skin and hair)

Medicinal Benefits

Melanocyl Solution contains methoxsalen, used along with controlled ultraviolet light in a treatment called psoralen plus ultraviolet light A (PUVA) to treat skin conditions such as vitiligo (discoloured patches in different areas of the body, including the skin and hair) and psoriasis (scaly, itchy, and red patches on the skin). It is used alongside ultraviolet-A radiation. It works by reducing the number of cells the skin makes.

Directions for Use

A physician will apply Melanocyl Solution only to a well-defined area of skin before the area is exposed to ultraviolet light A (UVA).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Melanocyl Solution

  • Skin irritation
  • Itching

Drug Warnings

Please inform your doctor if you are allergic to Methoxsalen or any other medicines. If you are pregnant or a nursing mother, it is advised to inform your doctor before using Melanocyl Solution. After UVA exposure, you are recommended to wash the treated area of your skin with soap and water. Then use sunscreen or wear protective clothing to protect the treated area. If you have squamous cell cancer (a form of skin cancer) or melanoma (a serious type of skin cancer), please inform your doctor beforehand. Wear special sunglasses during and for 24 hours after the treatment.

Drug Interactions

Drug-Drug Interaction: Inform your doctor if you are receiving concomitant therapy with photosensitizing agents (anthralin/dithranol, coal tar or its derivatives, phenothiazines, thiazides, griseofulvin, nalidixic acid, sulphonamides, salicylanilides, tetracyclines) and certain organic staining dyes (toluidine blue, methylene blue, methyl orange and rose Bengal).

Drug-Food Interaction: Avoid eating figs, parsley, mustard, parsnips, carrots, limes, and celery while being treated with Melanocyl Solution, as these may increase the skin’s sensitivity to sunlight.

Drug-Disease Interaction: Melanocyl Solution is contraindicated in patients with aphakia (missing lens inside the eye). If you have a specific history of light-sensitive disease states such as erythropoietic protoporphyria (rare inherited metabolic disorder), lupus erythematosus (autoimmune disease), xeroderma pigmentosum (extreme sensitivity to UV rays), variegate porphyria (inherited porphyria), albinism (group of genetic disorders that causes hair, skin or eyes to have little or no colour) and porphyria cutanea tarda (a type of blood disorder that affects the skin), please inform your doctor.

Drug-Drug Interactions Checker List

  • COAL TAR
  • GRISEOFULVIN
  • NALIDIXIC ACID
  • DITHRANOL
  • METHYLENE BLUE

Habit Forming

No

Diet & Lifestyle Advise

Vitiligo:

  • Minimize sun exposure. Use sunscreen with high SPF and protective sunglasses while going out in the sun.

  • Prefer using self-tanning lotions as they may help to even out skin tone and the effect lasts longer, even with washing.

Psoriasis:

  • Increase your intake of lean proteins containing omega-3 fatty acids, such as sardines, salmon, shrimp, flax seeds, walnuts and soybeans.

  • Avoid foods such as refined sugar, red meat, dairy products and highly processed foods, as these might trigger inflammation.

  • Avoid alcohol consumption as it may increase the risk of flare-ups.

  • Stress can also trigger psoriasis. Therefore, learn to manage and cope with stress by doing yoga, breathing, meditation, and journaling.

Disease/Condition Glossary

Psoriasis: It is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. These red patches can commonly appear on the scalp, elbows, knees, and lower back. Psoriasis is a noncontagious (not spread by contact) chronic immune condition with no cure. It can be mild, moderate, or severe based on the patch coverage on the skin. Psoriasis can be pustular, guttate, inverse, and erythrodermic. Pustular psoriasis mainly covers the palms of the hands and soles of the feet. Guttate psoriasis usually starts in childhood or young age and affects the torso and limbs. Inverse psoriasis forms bright red lesions in the armpits, groin, and under the breasts. Erythrodermic psoriasis is triggered by sunburn, infections, and certain medications that cause redness and shedding of the skin.

Vitiligo: It is a skin condition that causes loss of skin colour in blotches when melanocytes (cells that produce the colour) do not produce skin pigment, melanin (that gives the colour of skin). It can affect any part of the body, including hair, mouth and eyes. People with vitiligo must protect their skin from sunlight.

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Alcohol

Caution

The interaction of Melanocyl Solution with alcohol is unknown. Please discuss with your doctor if you have any concerns.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, please inform your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor before using Melanocyl Solution. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Safe

Melanocyl Solution usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Please inform your doctor if you have any liver diseases/conditions.

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Kidney

Consult your doctor

Please inform your doctor if you have any kidney diseases/conditions.

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Children

Consult your doctor

The safety of Melanocyl Solution in children has not been established. However, please consult a doctor if you have any concerns regarding this.

Country of origin

India

Manufacturer/Marketer address

20, Dr. E. Moses Road, Mahalaxmi, Mumbai - 400 011
Other Info - MEL0016

Author Details

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FAQs

Melanocyl Solution is used to treat Psoriasis (scaly, itchy, and red patches on the skin), and vitiligo (discoloured patches in different areas of the body, including the skin and hair).
Melanocyl Solution contains methoxsalen, which works by reducing the number of cells the skin makes. It is used alongside ultraviolet-A radiation.
Melanocyl Solution may increase skin sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn. Also, avoid sunbathing anytime during the course of treatment with Melanocyl Solution.
Melanocyl Solution may cause premature ageing of the skin as a result of prolonged therapy. This effect is similar to the result of sunbathing for a long duration.

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