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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:48 PM IST
Megatrum Ointment is used to treat the skin's burns and wounds. It also helps to treat wound infections after surgery. It helps in early wound healing and also prevents skin infection spread by harmful bacteria due to cuts, wounds and burns. It kills bacteria and other harmful organisms. It is used in degerming (physical removal of microbes), stasis ulcers (wound on the leg or ankle due to damaged veins), decubitus ulcers (bed sores) and the umbilical area. It may cause common side effects such as local swelling, itchiness, redness, small blisters and irritation at the application site. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, about all the medications you are taking and pre-existing medical conditions and if you are undergoing lithium therapy or radioactive iodine treatment.
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Manufacturer/Marketer :

Group Pharmaceuticals Ltd

Consume Type :

TOPICAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Megatrum Ointment

Megatrum Ointment belongs to the class of dermatological preparation called 'antibiotics' combined with 'antiseptic' primarily used to treat the skin's burns and wounds. It also helps to treat wound infections after surgery. Megatrum Ointment is abroad spectrum antibiotics, which help in early wound healing. Megatrum Ointment also prevents skin infection spread by harmful bacteria due to cuts, wounds and burns. 

Megatrum Ointment contains a combination of two medicines: Povidone-iodine and Metronidazole. Povidone Iodine can easily penetrate microorganisms and oxidise essential natural substances, leading to cell death. Metronidazole is an antibiotic which kills bacteria and other harmful organisms by damaging their DNA. Megatrum Ointment has broad-spectrum activity and is effective against many microbes, including gram-positive and gram-negative bacteria, fungi and protozoa. Megatrum Ointment is used in degerming (physical removal of microbes), stasis ulcers (wound on the leg or ankle due to damaged veins), decubitus ulcers (bed sores) and the umbilical area.

Megatrum Ointment is for external use only. Your doctor will decide the dose depending on the medical condition. Contact of Megatrum Ointment with eye should be avoided; if you accidentally touch eyes while applying Megatrum Ointment, please wash it immediately. Megatrum Ointment has common side effects, as every medicine does. These include local swelling, itchiness, redness, small blisters and irritation at the application site. These side effects gradually resolve during the treatment and do not require medical attention.

Brief your medical history to the doctor if you are allergic to Megatrum Ointment. Please consult your doctor if you are pregnant or planning to conceive before using Megatrum Ointment since it can affect the unborn baby. Using Megatrum Ointment during breastfeeding may increase the iodine levels in the breastmilk, which can cause hypothyroidism in breastfed infants. Let your doctor know if you have an overactive thyroid gland (hyperthyroidism), thyroid disease, or liver and kidney problems. Please tell your doctor if you are undergoing lithium therapy or radioactive iodine treatment. Megatrum Ointment should not be used before or after radioiodine scintigraphy or radioiodine treatment of thyroid carcinoma.

Uses of Megatrum Ointment

Treatment of Burns, Wound infection.

Directions for Use

Take the advised amount of cream/ointment with clean and dry hands on the skin's affected areas. Cover the open wounds with a sterile dressing or bandage after applying the Megatrum Ointment. Wash your hands before and after using Megatrum Ointment.

Medicinal Benefits

Megatrum Ointment is a combination medication containing Povidone-iodine (antiseptic) and Metronidazole (antibiotic) primarily used to treat and prevent skin infections in minor burns, lacerations (deep cut in the skin), cuts, and abrasions (the first layer of skin is scraped off). It is also used to treat postoperative wound infections. Povidone-iodine is an antiseptic applied on skin infected or likely to get infected. It slowly releases iodine, which kills or prevents the growth of these microorganisms. Metronidazole, being bactericidal in nature, kills the bacteria by damaging its genetic material (DNA) and preventing its growth, hence relieving the symptoms. Together, Megatrum Ointment prevents the growth of the microorganisms and promotes early wound healing.

Side Effects of Megatrum Ointment

  • Local swelling
  • Dry skin
  • Irritation
  • Redness
  • Itchiness

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Megatrum Ointment if you are allergic to povidone-iodine and metronidazole. Use Megatrum Ointment for the full recommended length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of another disease resistant to antibiotics. Avoid contact with your eyes, nose, or mouth. Rinse it off with water if you accidentally get the cream in these areas. Let your doctor know if you have an overactive thyroid gland (hyperthyroidism), any other thyroid diseases, or liver and kidney problems since the usage of Megatrum Ointment can cause iodine absorption into the body. This iodine absorption may lead to a rapid heartbeat (tachycardia) and restlessness, imbalance of electrolytes, abnormal blood concentration (osmolarity), and abnormal kidney function (renal impairment). Please tell your doctor if you are undergoing lithium therapy or radioactive iodine treatment. Megatrum Ointment should not be used before or after radioiodine scintigraphy or radioiodine treatment of thyroid carcinoma. Please consult your doctor if you are pregnant or planning to conceive before using the Megatrum Ointment since it can affect the unborn baby. Using Megatrum Ointment during breastfeeding may increase the iodine levels in the breastmilk, which can cause hypothyroidism in breastfed infants.

Therapeutic Class

ANTIBIOTICS- TOPICAL ANTIBIOTICS/ANTIMICROBIALS

Drug-Drug Interactions Checker List

  • SILVER NITRATE
  • LITHIUM
  • AMPRENAVIR
  • RITONAVIR
  • DISULFIRAM
  • WARFARIN
  • TAUROLIDINE
  • TIPRANAVIR
  • HYDROGEN PEROXIDE
  • TANNIC ACID

Diet & Lifestyle Advise

  • Use mild soap while taking baths and prefer warm baths.

  • Avoid harsh products on your skin.

  • Do not scratch or pick your skin to avoid infecting the affected area.

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

  • Do not walk barefoot at places like gym showers to prevent bacterial infections.

Habit Forming

No

How Megatrum Ointment Works

Megatrum Ointment contains a combination of two medicines: Povidone-iodine and Metronidazole. Povidone Iodine can easily penetrate microorganisms and oxidise essential natural substances, leading to cell death. Metronidazole is an antibiotic which kills bacteria and other harmful organisms by damaging their DNA.

What if I have taken an overdose of Megatrum Ointment

Overdose of Megatrum Ointment is not expected to be dangerous. However, do not use Megatrum Ointment in more doses or more often than prescribed. In case, anyone has swallowed Megatrum Ointment accidentally, please seek medical attention immediately.
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Alcohol

Caution

You are recommended not to consume alcohol while using medicines.

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Pregnancy

Caution

Using Megatrum Ointment during pregnancy may affect the unborn baby. Please consult your doctor before taking Megatrum Ointment if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Megatrum Ointment is not recommended during breastfeeding. When a breastfeeding mother uses Megatrum Ointment, it may increase the iodine levels in the breastmilk causing hypothyroidism in breastfed infants. Please consult your doctor before taking the Megatrum Ointment if you are breastfeeding.

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Driving

Safe

Megatrum Ointment is generally safe to use before driving. However, if you notice any side effects like dizziness or burning sensation in the affected areas, avoid driving and operating machinery until you feel better.

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Liver

Not applicable

Megatrum Ointment can be given in case of any liver impairment or problem.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Megatrum Ointment, since it may lead to abnormal kidney function (renal impairment) and an imbalance of electrolytes.

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Children

Consult your doctor

Your doctor will recommend Megatrum Ointment depending on your child's severity of infection or wounds.

Country of origin

INDIA

Manufacturer/Marketer address

Devraj Bldg, \'A\' Wing, 4th Floor, S.V.Road, Goregoan West, Mumbai - 400 062, India.
Other Info - MEG0244

Author Details

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FAQs

Megatrum Ointment is a combination of antiseptic and antibiotic medicines that help treat skin infections, such as wounds, burns and cuts.
Megatrum Ointment works by inhibiting the growth of infection-causing microbes. As a small molecule, Iodine in Megatrum Ointment can easily penetrate microorganisms and oxidize essential proteins, nucleotides, and fatty acids, leading to cell death.
Please consult your doctor if you use other topical medicines before starting Megatrum Ointment. However, products containing enzymatic components, alkali, mercury, silver, hydrogen peroxide, tannic acid and taurolidine may interact with Megatrum Ointment and should not be used simultaneously.
Megatrum Ointment should be used with proper caution and doctor consultation if you have any liver disease, kidney disease, goitre (abnormal enlargement of the thyroid gland), thyroid nodules or other non-acute thyroid diseases. Please tell your doctor if you are undergoing any lithium therapy or radioactive iodine treatment.
Megatrum Ointment is not recommended for use if you are undergoing lithium therapy or radioactive iodine treatment. Megatrum Ointment should not be used before or after radioiodine scintigraphy or radioiodine treatment of thyroid carcinoma. In such conditions, please consult your doctor before using Megatrum Ointment.
Megatrum Ointment may interfere with thyroid function tests due to iodine absorption. Please ask your doctor before starting Megatrum Ointment if you have any history of thyroid problems. A Megatrum Ointment can also show false-positive lab results, such as tests with toluidine or gum guaiac, to determine haemoglobin or glucose in the stool or the urine.
The common side effects of Megatrum Ointment may include local swelling, itchiness, redness, small blisters, and irritation at the application site. Most of these side effects do not require medical attention and will gradually resolve. However, you are advised to consult your doctor if the side effects persist or worsen.
Megatrum Ointment should be used for the duration recommended by your doctor, based on the specific condition being treated. To avoid relapse, complete the full course of treatment, even if symptoms improve early. If you notice signs of infection or the wound is not improving, please consult your doctor for personalized guidance. Your doctor may extend the treatment period or adjust the plan as needed.
Yes, Megatrum Ointment is an antibiotic that helps with early wound healing. It contains metronidazole, an antibiotic that targets bacteria and certain protozoa, and povidone-iodine, an antiseptic with broad antimicrobial properties (effective against gram-positive and gram-negative bacteria, fungi, and protozoa).
Megatrum Ointment should be stored in a cool and dry place, away from direct sunlight and moisture; keep it out of reach of children.

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