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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:53 PM IST
Mdox 100mg Tablet DT is used to treat bacterial infections. It treats urinary tract infections, intestinal infections, respiratory infections, eye infections, sexually transmitted infections (like gonorrhoea and syphilis), gum infections, diseases (like periodontitis), and others. Besides this, it also treats acne-like lesions caused by rosacea. However, it does not treat facial redness caused by rosacea. It contains Doxycycline, which prevents the growth of bacteria. It may cause some common side effects such as nausea, vomiting, diarrhoea, etc. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Mdox 100mg Tablet DT

Mdox 100mg Tablet DT is used to treat bacterial infections. Mdox 100mg Tablet DT treats urinary tract infections, intestinal infections, respiratory infections, eye infections, sexually transmitted infections (like gonorrhoea and syphilis), gum infections, diseases (like periodontitis), and others. Besides this, Mdox 100mg Tablet DT also treats acne-like lesions caused by rosacea. However, it does not treat facial redness caused by rosacea. 

Mdox 100mg Tablet DT being an antibiotic prevents the growth of bacterial cells (the bad ones!) by preventing the formation of the outer protein layer of bacteria (cell wall) responsible for bacteria's growth and multiplication. It is a broad-spectrum antibiotic, i.e. it acts against various bacteria. It is a bacteriostatic antibiotic, i.e. it stops bacteria growth but does not kill them.

Mdox 100mg Tablet DT should only be taken if advised by your doctor. It can be taken with or without food but should be consumed at a fixed time for the best results. You should complete the course of Mdox 100mg Tablet DT as your doctor prescribes for better results. Some common side effects of Mdox 100mg Tablet DT are nausea (feeling or being sick), vomiting, diarrhoea, etc. Please consult your doctor if these side effects become troublesome.

Mdox 100mg Tablet DT is pregnancy category D (high risk) medicines, so its use in pregnant and nursing mothers is not recommended. Use of Mdox 100mg Tablet DT during tooth development (last half of pregnancy, infancy, and childhood up to the age of 8 years) may cause teeth staining (yellow-grey-brown). Do not consume alcohol as it may cause excessive drowsiness when taken along with Mdox 100mg Tablet DT. Before using Mdox 100mg Tablet DT, tell your doctor if you ever had an allergy to Mdox 100mg Tablet DT, have kidney problems, liver problems, swollen food pipe (esophagitis) or muscle disease (myasthenia gravis). Please do not drink alcohol with Mdox 100mg Tablet DT as it may increase the unpleasant side effects like drowsiness and dizziness.

Uses of Mdox 100mg Tablet DT

Treatment of Bacterial infections

Medicinal Benefits

Mdox 100mg Tablet DT is a type of tetracycline class of antibiotic which is effective against a wide range of bacteria, including gram-negative and gram-positive bacteria, anaerobes, and some parasites. It is prescribed for treating various bacterial infections of the respiratory tract (influenza, pneumonia), genitourinary area (syphilis, gonorrhoea), anthrax infection, sinuses, eyes, and skin. Besides this, it is also indicated in the tick-borne infections (typhus fever) caused by the Rickettsia group of bacteria like typhus fever. Off-label, usage includes the prophylaxis or prevention of malaria in the prone area and the treatment of acne. Sometimes, your doctor might prescribe you Mdox 100mg Tablet DT as an alternative medicine to penicillin when penicillin is contraindicated.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mdox 100mg Tablet DT

  • Nausea (feeling sick)
  • Vomiting
  • Diarrhoea

Drug Warnings

Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Mdox 100mg Tablet DT in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Mdox 100mg Tablet DT and iron supplements and antacids. Prolonged use of Mdox 100mg Tablet DT during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may cause permanent discolouration of the teeth (yellow-grey-brown). Besides this, in some cases, the use of Mdox 100mg Tablet DT causes antibiotic-associated diarrhoea. Mdox 100mg Tablet DT may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like (vaginal candidiasis - thrush). Tetracycline and Mdox 100mg Tablet DT can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the foetus. Using a Mdox 100mg Tablet DT with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Mdox 100mg Tablet DT may affect your blood, kidney, and liver health, so yearly diagnostics test of these parameters is recommended. Mdox 100mg Tablet DT does not completely prevent malaria caused by P. falciparum as a Mdox 100mg Tablet DT is given only for the prophylactic regimen (protection) whenever anyone enters a malaria-prone area.

Drug Interactions

Drug-Drug Interactions: Mdox 100mg Tablet DT is contraindicated in persons who have shown hypersensitivity to any of the tetracycline or penicillin, retinoid medications taken by mouth (such as acitretin, isotretinoin), blood thinners (such as warfarin), heart disease medicine (digoxin), anti-seizure medications (such as phenytoin, carbamazepine), antacids (especially those containing aluminium, calcium, or magnesium, bismuth subsalicylate), iron supplements, and oral birth control pills. 

Drug-Food Interactions: Food containing calcium and iron should be avoided within 2 hours of Mdox 100mg Tablet DT as it may affect Mdox 100mg Tablet DT effectiveness. Avoid alcohol intake as it may lead to drowsiness and affect Mdox 100mg Tablet DT absorption.

Drug-Disease Interactions: Mdox 100mg Tablet DT should not be given to people with kidney problems, liver problems, swollen food pipe (esophagitis), lupus disease (an autoimmune disease), muscle disease (myasthenia gravis).

Drug-Drug Interactions Checker List

  • ACITRETIN
  • ISOTRETINOIN
  • WARFARIN
  • DIGOXIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • BISMUTH SUBSALICYLATE

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Mdox 100mg Tablet DT to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.

  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Mdox 100mg Tablet DT.

  • Avoid intake of alcoholic beverages with Mdox 100mg Tablet DT as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Mdox 100mg Tablet DT in fighting off infections.

Special Advise

  • Mdox 100mg Tablet DT is preferably taken empty stomach or 1-2 hours before meals but it can lead to stomach upset. To avoid this, you may take Mdox 100mg Tablet DT with meals but ensure you drink plenty of water to keep yourself hydrated.
  • To prevent throat irritation take Mdox 100mg Tablet DT in an upright position. Do not lie down for at least 30 minutes of taking it. 
  • Even if you feel better after taking Mdox 100mg Tablet DT, do not stop taking it until your doctor says so. This might cause the symptoms to reappear and will make the infection difficult to treat due to antibiotic resistance.
  • Mdox 100mg Tablet DT can affect growing teeth, so it should be avoided during pregnancy and in children less than 8 years old.
  • Mdox 100mg Tablet DT should not be consumed beyond its expiry date as after that it breaks down into harmful chemicals which can damage the kidney.
  • Make sure you drink plenty of fluids when you are sick. This will in general help you clear out the infection faster, protect you from dehydration, and will help you overcome some unpleasant side effects of taking Mdox 100mg Tablet DT.
  • Wear sunglasses and sunscreen when you go out in the sun as Mdox 100mg Tablet DT can make your skin sensitive to light.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. A few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E.coli. Anyone can become infected with a bacterial infection. However, people with weak immune systems or taking immunosuppressive medicine can be more prone to bacterial infection.

Rosacea: Rosacea is a skin infection that causes a persistent redness in the centre of your face. Small blood vessels on the cheeks and nose are often inflamed and red. Many people with rosacea also develop pimples on their faces, similar to acne.

Antibiotic-induced diarrhoea: Antibiotic-induced diarrhoea or Antibiotic-associated diarrhoea refers to the occurrence of diarrhoea (passing loose, watery stools more than 3 times per day) after taking antibiotics. It happens because antibiotics also kill beneficial intestinal bacteria (gut flora), which aids in food digestion and fighting off infections.  

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Alcohol

Unsafe

Mdox 100mg Tablet DT should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Mdox 100mg Tablet DT is a Pregnancy Category D. There are no adequate and well-controlled studies on the use of doxycycline in pregnant women. In some cases, taking Mdox 100mg Tablet DT during pregnancy may affect tooth and bone development in the unborn baby. So, if you are pregnant or planning for pregnancy contact the doctor before using a Mdox 100mg Tablet DT.

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Breast Feeding

Caution

Mdox 100mg Tablet DT is excreted in the breast milk however, the extent of absorption of Mdox 100mg Tablet DT, by the breastfed infant is not known. Hence, the nursing mother before using a Mdox 100mg Tablet DT should contact the doctor.

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Driving

Safe if prescribed

The effect of doxycycline on the ability to drive or operate heavy machinery has not been fully studied but there is no evidence to suggest that doxycycline may affect the ability to drive. Discuss with your doctor if you have any concerns or are having unusual sleepiness or drowsiness after taking Mdox 100mg Tablet DT.

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Liver

Caution

Mdox 100mg Tablet DT to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

At the recommended doses, Mdox 100mg Tablet DT is safe to use in patients with kidney disease and no dose adjustment is warranted. If prescribed by a doctor, Mdox 100mg Tablet DT can be safely used. But it is best to discuss with your doctor if you have a known kidney disease/condition.

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Children

Unsafe

Use of Mdox 100mg Tablet DT during tooth development in infants and children below 8 years of age may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for children below 8 years of age.

Country of origin

India
Other Info - MD69914

FAQs

Mdox 100mg Tablet DT is used to treat bacterial infections like urinary tract infections, intestinal infections, respiratory infections, eye infections, sexually transmitted infections, and gum infections.
Mdox 100mg Tablet DT being an antibiotic prevents the growth of bacterial cells (the bad ones!)Â by preventing the formation of the outer protein layer of bacteria (cell wall) responsible for bacteria's growth and multiplication. It is a broad-spectrum antibiotic, i.e. it acts against various bacteria. It is a bacteriostatic antibiotic, i.e. it stops bacteria growth but does not kill them.
No, Mdox 100mg Tablet DT should not be stopped even if you feel better as it is an antibiotic medication and completing the full course if very necessary, otherwise the infection might re-appear in a more severe form and will also become difficult to treat due to antibiotic resistance.
If you are taking Mdox 100mg Tablet DT, avoid taking antacids containing aluminium, calcium or magnesium or other drugs containing these cations; oral zinc, iron salts or bismuth preparations within 2 hours of consumption of Mdox 100mg Tablet DT as they may affect the absorption of Mdox 100mg Tablet DT from the stomach. Avoid taking dairy products within 2 hours of taking Mdox 100mg Tablet DT as they also impair the absorption of Mdox 100mg Tablet DT.
Use of Mdox 100mg Tablet DT during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for pregnant women, breastfeeding mothers, and children below 8 years of age.
Yes. Intake of Mdox 100mg Tablet DT may increase your skin sensitivity to the sun rays or ultraviolet lights. So, it is better to apply any sunscreen lotions on your skin whenever you step out of your home.
Yes. Intake of Mdox 100mg Tablet DT may lead to overgrowth of fungal skin infections like candida. This happens because Mdox 100mg Tablet DT also kills good or beneficial bacteria that protect against thrush. If such symptoms occur reach out to your doctor.
Mdox 100mg Tablet DT generally does not affect any contraception, including the birth control pill and emergency contraceptive pills. However, if you develop vomiting or have diarrhoea, your birth control pill may not protect you from pregnancy. Please consult your doctor if you have any concerns regarding using the Mdox 100mg Tablet DT.
Yes, you can drink milk while taking Mdox 100mg Tablet DT, as it does not significantly affect its absorption. If you experience gastric irritation, it is recommended to take Mdox 100mg Tablet DT with milk to reduce this discomfort.
If you are taking Mdox 100mg Tablet DT for gum infections or rosacea (a chronic skin condition that causes redness and acne-like bumps on the face), it is recommended to take the medicine at least 1 hour before eating. For other types of infections, you can take Mdox 100mg Tablet DT with or without food.
Yes, if you are experiencing stomach upset, it is recommended to take Mdox 100mg Tablet DT with food or milk to help ease the discomfort.
For most infections, you will start to feel better within a few days. However, it's important to finish the full course of medication as prescribed by your doctor. Mdox 100mg Tablet DT works more slowly when used to treat conditions like rosacea.
Yes, Mdox 100mg Tablet DT can cause diarrhoea as a side effect. This occurs because Mdox 100mg Tablet DT can disrupt the balance of gut bacteria, leading to digestive issues. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If diarrhoea is severe or persists, please consult your doctor.
Mdox 100mg Tablet DT can be used in children above 8 years, as it may cause permanent discoloration of teeth or problems with bone growth in younger children. However, a doctor may recommend Mdox 100mg Tablet DT for younger children with conditions like Rocky Mountain spotted fever (a bacterial disease spread by tick bites) or inhalational anthrax (a severe respiratory infection caused by inhaling spores of the Bacillus anthracis bacteria) if they think it's necessary.
Yes, Mdox 100mg Tablet DT is commonly prescribed to treat acne. It is an antibiotic that works by killing the bacteria that infect the pores and reducing the production of a certain oily substance that contributes to acne.
No, pregnant and breastfeeding women should avoid taking Mdox 100mg Tablet DT (Pregnancy D category drug) unless prescribed by a doctor. Mdox 100mg Tablet DT may potentially harm a developing foetus by affecting bone and teeth development. For breastfeeding mothers, Mdox 100mg Tablet DT can pass into breast milk, which may be harmful to the baby. Therefore, if you are pregnant, planning to become pregnant, or breastfeeding, please consult your doctor before using Mdox 100mg Tablet DT.
The common side effects associated with Mdox 100mg Tablet DT include nausea (feeling sick), vomiting, and diarrhoea. If these side effects become troublesome, please consult your doctor.
No, do not consume alcohol while taking Mdox 100mg Tablet DT as it lowers the effectiveness of the medicine and might increase the risk of side effects.
Store Mdox 100mg Tablet DT in a cool, dry place, away from light and moisture. Keep it out of reach of children.
You should take Mdox 100mg Tablet DT for as long as your doctor prescribes it. The duration of treatment depends on the condition being treated. For most infections, it is commonly prescribed for 7–10 days. However, for conditions like acne or anthrax, it may be prescribed for a longer period.
Before starting treatment with Mdox 100mg Tablet DT, you should discuss any existing medical conditions with your doctor, especially liver or kidney diseases. Inform your doctor if you are allergic to any of the ingredients in Mdox 100mg Tablet DT or to antibiotics. Mdox 100mg Tablet DT may reduce the effectiveness of hormonal contraceptives (birth control pills), so inform your doctor if you are using any hormonal contraceptives before starting the medication. Be sure to let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding. Additionally, mention any other medications or supplements you are currently taking to avoid potential interactions.
Mdox 100mg Tablet DT is usually taken once or twice a day, ideally in the morning or evening. It should be swallowed with a full glass of water. For optimal absorption, it is best to take Mdox 100mg Tablet DT on an empty stomach, at least 1 hour before or 2 hours after meals. Avoid lying down for at least 30 minutes after taking it.

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