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Reviewed By , M Pharmacy
Last Updated Jan 1, 2025 | 9:32 AM IST

Mabvinra 40 mg Injection is used to help reduce signs and symptoms of autoimmune disorders such as Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn's disease, Uveitis and Ulcerative colitis. It consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

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Composition :

ADALIMUMAB-40MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Apr-26

About Mabvinra 40 mg Injection

Mabvinra 40 mg Injection  belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors that help reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, plaque psoriasis, and psoriatic arthritis. This medicine is also used in the treatment of Crohn’s disease, ulcerative colitis, hidradenitis suppurativa, and uveitis.

Mabvinra 40 mg Injection consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

Mabvinra 40 mg Injection may cause certain side effects such as nausea, headache, back pain, upper respiratory tract infections, vision problems, dizziness, pale skin, numbness, chest pain, rash, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. Mabvinra 40 mg Injection is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. Your physician will decide the dose and duration of the medicine based on the type and severity of the condition.

Mabvinra 40 mg Injection should be avoided if you are allergic to any of its components.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, hepatitis B virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system, as it can worsen your health condition. Mabvinra 40 mg Injection may cause dizziness, so drive only if you are alert and focused. Mabvinra 40 mg Injection should not be given to children under two years of age as safety has not been established. Consult the doctor if you are pregnant or breastfeeding.

Uses of Mabvinra 40 mg Injection

Treatment of Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn's disease, Uveitis and Ulcerative colitis

Medicinal Benefits

Mabvinra 40 mg Injection consists of Adalimumab, which belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain, redness, and inflammation (swelling) caused by various autoimmune diseases.

Side Effects of Mabvinra 40 mg Injection

  • Tingling or numbness
  • Shortness of breath
  • Vision problems
  • Injection site reactions
  • Headache
  • Nausea
  • Upper respiratory tract infections.
  • Chest pain

Directions for Use

Mabvinra 40 mg Injection will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Mabvinra 40 mg Injection should be avoided if allergic to it or any other components present. Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, hepatitis B virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), or diabetes as it can worsen your health condition. Do not take live vaccines while being treated with Mabvinra 40 mg Injection to prevent any serious consequences. Mabvinra 40 mg Injection is not recommended for use in children below two years of age as safety and efficacy are not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Therapeutic Class

IMMUNOSUPPRESSANTS

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • Stay hydrated; drink plenty of water.

Habit Forming

No

How Mabvinra 40 mg Injection Works

Mabvinra 40 mg Injection consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

What if I have taken an overdose of Mabvinra 40 mg Injection

Since Mabvinra 40 mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Mabvinra 40 mg Injection . Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Mabvinra 40 mg Injection . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Mabvinra 40 mg Injection .

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Driving

Caution

Mabvinra 40 mg Injection will be administered in the hospital setting. Hence, driving is not recommended.

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Liver

Caution

Mabvinra 40 mg Injection should be used with caution if you have liver disease. Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Mabvinra 40 mg Injection should be used with caution if you have kidney disease. Dose adjustment may be needed in patients with liver impairment.

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Children

Caution

Mabvinra 40 mg Injection is not recommended in children below two years of age as safety and efficacy are not established. In children above two years of age, it will be administered by the pediatrician. Mabvinra 40 mg Injection is used in children only for the treatment of juvenile idiopathic arthritis, paediatric Crohn’s disease, and uveitis.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - MAB0028

Author Details

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FAQs

Mabvinra 40 mg Injection is used to treat Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn’s disease, Uveitis and Ulcerative colitis.
Mabvinra 40 mg Injection contains Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive.
Mabvinra 40 mg Injection affects your immune system and makes you more susceptible to infections. Hence, it is not recommended in people with active infections like tuberculosis or abnormal liver enzymes. Mabvinra 40 mg Injection can also increase the risk of developing cancers; hence, informing your doctor if you have a history of any cancer is essential.
Mabvinra 40 mg Injection is an antirheumatic medicine that belongs to the TNF (tumor necrosis factor) inhibitor class. It contains the active ingredient Adalimumab.
Treatment with Mabvinra 40 mg Injection can help reduce inflammation, pain, redness, and swelling associated with various autoimmune disorders.
Mabvinra 40 mg Injection which contains Adalimumab, can weaken your immune system. Since it affects the immune system, it may increase your risk of developing infections. It is important to follow your doctor's advice and inform them if you have any existing infections or health concerns before starting treatment.
Mabvinra 40 mg Injection can be used alongside other arthritis medicines such as methotrexate, prednisolone, naproxen, ibuprofen, and paracetamol. However, Mabvinra 40 mg Injection should not be used with other biological disease-modifying antirheumatic drugs (bDMARDs).
Mabvinra 40 mg Injection should be stopped before surgery. It can be resumed after the operation, once the wound has healed and there is no infection, as determined by your surgeon and rheumatologist.
Mabvinra 40 mg Injection causes side effects such as rash, headache, sinusitis, upper respiratory infections, fever, and application site reactions. Therefore, please contact a doctor if these do not reduce and persist for longer durations.

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