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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:54 PM IST
Lufixcin 200 mg Tablet is used for the treatment of a wide range of bacterial infections of the skin, ears, lungs, prostate and urinary tract. Besides this, it also treats typhoid fever and STDs (sexually transmitted diseases) like chlamydia and gonorrhoea. It contains Cefixime and Ofloxacin, which works by preventing the formation of the outer covering of the bacteria (cell wall) required for their survival. It prevents the release of a chemical messenger (mucopeptides) by the bacteria, thereby weakening and destroying the bacterial cell wall. It may cause some common side effects such as diarrhoea, indigestion, nausea, loose stools, abdominal pain, and vomiting.
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Prescription drug

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Manufacturer/Marketer

Lupin Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Lufixcin 200 mg Tablet

Lufixcin 200 mg Tablet belongs to a group of medications called 'cephalosporin antibiotics' primarily used for the treatment of a wide range of bacterial infections of the skin, ears, lungs, prostate and urinary tract. Besides this, it also treats typhoid fever and STDs (sexually transmitted diseases) like chlamydia and gonorrhoea. A bacterial infection happens when harmful bacteria enter inside the body and start multiplying. These harmful bacteria are responsible for producing toxins that can cause diseases like strep throat, urinary tract infection (UTI), bacterial food poisoning, gonorrhoea, bacterial meningitis, cellulitis, Lyme disease, and tetanus. Lufixcin 200 mg Tablet does not work against viral infections like flu and colds.

Lufixcin 200 mg Tablet contains 'Cefixime' (cephalosporin antibiotic) and 'Ofloxacin' (fluoroquinolone antibiotic) that works by preventing the formation of the outer covering of the bacteria (cell wall) required for their survival. Lufixcin 200 mg Tablet prevents the release of a chemical messenger (mucopeptides) by the bacteria, thereby weakening and destroying the bacterial cell wall. Lufixcin 200 mg Tablet is a broad range antibiotic that works against a wide range of both gram-positive and gram-negative bacteria.

Take Lufixcin 200 mg Tablet as prescribed. Your doctor will recommend how often you take Lufixcin 200 mg Tablet based on your medical condition. Lufixcin 200 mg Tablet may cause some common side effects that include diarrhoea, indigestion, nausea, loose stools, abdominal pain, and vomiting. However, some of these side effects do not require medical attention and will pass within a couple of days. If side effects become get worse with time or do not pass within a couple of days, then one should consult their doctor. 

Lufixcin 200 mg Tablet is not allowed to use in patients who are already taking any of the other antibiotics or having kidney or liver problems. This medicine can only be used in pregnant or breastfeeding women if strongly suggested by the doctor. Ofloxacin present in Lufixcin 200 mg Tablet may cause and aggravate symptoms of existing peripheral neuropathy (nerve damage in legs), tendinitis (swelling or tearing of a tendon), myasthenia gravis (skeletal muscle weakness), and respiratory issues like bronchitis, sinusitis. People with diabetes should contact a doctor before taking Lufixcin 200 mg Tablet as Lufixcin 200 mg Tablet can lower your blood sugar level in some cases. Patient with central nervous system disorder or epilepsy (fits) should avoid intake of Lufixcin 200 mg Tablet as its use is contraindicated for them.

Uses of Lufixcin 200 mg Tablet

Treatment of Bacterial infections, Typhoid fever, Urinary tract infection (UTI)

Medicinal Benefits

Lufixcin 200 mg Tablet is a combination of cephalosporin and fluoroquinolone antibiotics that works by killing the bacteria (bactericidal). Cefixime works by stopping the growth of bacteria by inhibiting the formation of a protective layer required by the bacteria or its growth. At the same time, Ofloxacin acts by blocking the action of a chemical messenger, which helps the genetic material of bacteria to survive. The doctor usually prescribes Lufixcin 200 mg Tablet for the treatment of typhoid fever and urinary tract infections. Besides this, it also treats bacterial infections of the prostate, skin, lungs, sexually transmitted infections like gonorrhoea (cervical/urethral), ear infections (acute otitis media), upper respiratory tract infections (URTI), lower respiratory tract infection, tonsillitis (inflammation of the tonsils) and pharyngitis (inflammation of the pharynx). 

Directions for Use

Tablet: Take it with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.Tablet DT: Take it with food as advised by the doctor. Disperse the tablet in a spoonful (15ml) of boiled and cooled water. Consume immediately.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lufixcin 200 mg Tablet

  • Diarrhoea
  • Nausea
  • Dyspepsia (Indigestion)
  • Loose stools
  • Abdominal pain
  • Vomiting

Drug Warnings

You should avoid taking Lufixcin 200 mg Tablet if you are hypersensitive to ofloxacin, cefixime or other macrolide antibiotics as it may lead to overdose and toxicity. The use of Lufixcin 200 mg Tablet is only allowed in pregnancy or breastfeeding if clearly suggested by the doctor. Tell your doctor if you are pregnant, or breastfeeding before using Lufixcin 200 mg Tablet . Ofloxacin present in Lufixcin 200 mg Tablet may cause and aggravate symptoms of existing peripheral neuropathy (nerve damage in legs), tendinitis (swelling or tearing of a tendon), myasthenia gravis (skeletal muscle weakness), and respiratory issues like bronchitis, sinusitis. People with diabetes should contact a doctor before taking Lufixcin 200 mg Tablet as Lufixcin 200 mg Tablet can lower your blood sugar level in some cases. Patient with central nervous system disorder or epilepsy (fits) should avoid intake of Lufixcin 200 mg Tablet as its use is contraindicated for them. 

Drug Interactions

Drug-Drug Interaction: Lufixcin 200 mg Tablet should be avoided to be taken with vaccines including typhoid vaccine, cholera vaccine, and Bacillus Calmette Guerin (BCG vaccine), antiepileptic (carbamazepine), blood thinner (warfarin), antacid and ulcer treating medicine (aluminium hydroxide, magnesium hydroxide, cimetidine, sucralfate), medicine to treat excess uric acid (probenecid), medicines for arthritis (methotrexate), diuretics/water pills (furosemide), asthma medicine (theophylline) and pain killers (fenbufen, ibuprofen). 

Drug-Food Interaction: A person should limit the consumption of eating a high-fat meal as this makes it harder for your body to absorb Lufixcin 200 mg Tablet . Do not consume grapefruit during antibiotics treatment can prevent the body from utilizing Lufixcin 200 mg Tablet properly. So, prevent intake of grapefruit or grapefruit juice with the antibiotic. Avoid consuming calcium enriched foods and drinks as it might affect the working of Lufixcin 200 mg Tablet . 

Drug-Disease Interaction: People affected with diabetes mellitus, renal dysfunction, liver disease, seizure disorders, colitis (bowel disease that affects the large intestine, causing irritation, inflammation, and ulcers in the colon) should not take Lufixcin 200 mg Tablet .

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • BACILLUS CALMETTE-GUERIN(BCG) VACCINE
  • CHOLERA VACCINE
  • TYPHOID VACCINE
  • CARBAMAZEPINE
  • WARFARIN
  • CIMETIDINE
  • SUCRALFATE
  • METHOTREXATE
  • THEOPHYLLINE
  • IBUPROFEN
  • MAGNESIUM HYDROXIDE
  • ALUMINUM HYDROXIDE
  • LORATADINE

Habit Forming

No

Diet & Lifestyle Advise

  • Include probiotics in your diet as probiotics contain healthy bacteria that are good for the intestines and can recover the killed bacteria.
  • Taking probiotics after completing the antibiotics course can minimize the chances of antibiotic-associated diarrhoea. Foods that are high in probiotics include yoghurt, cheese, sauerkraut, and kimchi so consume them to restore the good bacteria of the intestine. 
  • Try to take more fibre-enriched food as it will help the food to digest properly and helps to stimulate the growth of gut bacteria.
  • Include whole grains like whole-grain bread, brown rice to include fibre in your diet.
  • Try to consume less calcium, iron-enriched foods, and drinks as it may slow down the working of Lufixcin 200 mg Tablet . 
  • Try to limit the consumption of alcoholic beverages as it can cause worsening of side effects and make your body dehydrated and affect your sleep. This also makes it difficult for your body to aid the Lufixcin 200 mg Tablet in fighting off infections.

Special Advise

If you experience diarrhoea or CDAD (C. difficile-associated disease) immediately contact a doctor or nearby clinic as you might require sufficient electrolyte and other interventions for preventing water loss or dehydration. 

Disease/Condition Glossary

Bacterial infection: The bacterial infection occurs when harmful bacteria enter, and get multiplied, and cause sickness inside the body. Common symptoms of bacterial infection may vary depending upon the type of infection and bacteria, causing it. Some other symptoms of a bacterial infection include fever, feeling tired, swollen lymph nodes, headache, nausea, or vomiting. Bacteria are single-celled small microorganisms found in different shapes and structures like spherical, rod, and spiral-shaped.  Some harmful bacteria that can affect a human's body include Streptococcus, Staphylococcus, and E. coli. Bacterial infection can infect anyone persons with a weak immune system or already taking immunosuppressive drugs are at higher risk of bacterial infection. 

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Alcohol

Caution

It is best to limit the consumption of alcohol as it may worsen the side effects of Lufixcin 200 mg Tablet .

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Pregnancy

Caution

Lufixcin 200 mg Tablet should only be given in pregnancy if clearly suggested by the doctor after weighing the benefits and potential risks of medication.

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Breast Feeding

Unsafe

Lufixcin 200 mg Tablet should be suggested to breastfeeding mothers only if the doctor has judged it to outweigh the potential risks to the infant. Hence one should consult with their doctor before taking Lufixcin 200 mg Tablet .

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Driving

Caution

A person should avoid driving as it may cause impaired vision and affect thinking ability.

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Liver

Caution

Lufixcin 200 mg Tablet should be taken with caution in patients having a history of liver diseases/conditions. The doctor may suggest lower doses initially.

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Kidney

Caution

Lufixcin 200 mg Tablet to be taken with caution, especially in persons having a history of Kidney disorders. The doctor may initially suggest a lower dose of initially.

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Children

Caution

Lufixcin 200 mg Tablet to be given to children below the age of 12 with caution only if clearly prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - LUF0006

Author Details

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FAQs

Lufixcin 200 mg Tablet is used for the treatment of a wide range of bacterial infections of the skin, ears, lungs, prostate and urinary tract. Besides this, it also treats typhoid fever and STDs (sexually transmitted diseases) like chlamydia and gonorrhoea.
No, you should not double the dose if you forget to take Lufixcin 200 mg Tablet , then take it as soon as you remember or skip it if it's time for the next dose.
Yes, some patients may experience diarrhoea, after taking this medicine so it is better to take this drug after a meal which reduces the risk of stomach discomfort. However, If you are noticing diarrhoea that is watery or bloody, then immediately ask your doctor. Do not try to take self-medication for diarrhoea without asking the doctor.
Yes, this medicine is prescribed for the treatment of urinary tract infection (UTI). Take Lufixcin 200 mg Tablet only if the doctor has prescribed you this medicine.
You should avoid driving as this medicine may cause impaired vision or affect the thinking ability so avoid such a task that needs a clear vision.
You should avoid taking Lufixcin 200 mg Tablet if you have peripheral neuropathy (nerve damage in legs), tendinitis (swelling or tearing of a tendon), myasthenia gravis (skeletal muscle weakness), respiratory issues like bronchitis, sinusitis, diabetes, central nervous system disorder, or epilepsy (fits).
No, Lufixcin 200 mg Tablet is not advised for viral infections, such as the common cold. It is a strong antibiotic used to treat severe bacterial infections.
You are advised to take Lufixcin 200 mg Tablet as recommended by your doctor. Complete the full treatment as prescribed to show its effectiveness, as discontinuing suddenly may cause antibiotic resistance.
No, Lufixcin 200 mg Tablet is not recommended for viral infections. Lufixcin 200 mg Tablet is an antibiotic used to treat bacterial infections. Do not self-medicate.
Lufixcin 200 mg Tablet doesn’t respond against the viral infections such as cough. Therefore, if you have cough, consult your doctor for appropriate medication.
Yes, cefix contains cefixime as its active substance and is an antibiotic used to treat bacterial infections of urinary tract, lungs, throat, airways, tonsils, middle ear, and cervical or urethral regions.
Take Lufixcin 200 mg Tablet as recommended by your doctor. Taking Lufixcin 200 mg Tablet with milk may potentially affect its effectiveness.
No, do not take Lufixcin 200 mg Tablet for stomach infections as it could be due to various reasons. Also, avoid taking Lufixcin 200 mg Tablet for any infection without doctor’s advice.
Yes, Lufixcin 200 mg Tablet is a strong antibiotic that can treat various bacterial infections. Do not self-medicate.
Lufixcin 200 mg Tablet can be used for sinus infections (sinusitis) if caused by bacteria and if it is advised by a doctor. However, please consult a doctor as it varies for everyone based on your health condition.
No, do not take Lufixcin 200 mg Tablet on your own as inappropriate usage of antibiotics may cause failure of the treatment in future.
The dosage of Lufixcin 200 mg Tablet treatment vary based on the specific condition and patient response to the medication. If you do not notice any improvement within 3-4 days of starting the treatment, please consult your doctor. Do not self-medicate.
Lufixcin 200 mg Tablet contains Cefixime (cephalosporin antibiotic) and Ofloxacin (fluoroquinolone antibiotic) as its active substances.
Consult your doctor if you don’t get better after using Lufixcin 200 mg Tablet . Also, inform about the unwanted effects and the symptoms that worsen while using Lufixcin 200 mg Tablet .
UTIs are usually treated with antibiotics. To prevent UTIs, it's important to stay hydrated, urinate after sex, avoid irritating female hygiene products, and wear cotton underwear. For frequent UTIs, doctors may recommend low-dose antibiotics or other preventive options, including probiotics.
Store Lufixcin 200 mg Tablet at room temperature. Protect from light. Keep it out of reach from children. Disposal of Lufixcin 200 mg Tablet is done by following the local guidelines.

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