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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:27 PM IST

Kelfer-250Mg Capsule is used to treat iron overload caused by frequent blood transfusions in patients with thalassemia syndromes when current chelation therapy is inadequate. It contains Deferiprone, which works by attaching to iron and helps your body pass the extra iron out in the urine. Thus, it helps treat iron overload. In some cases, Kelfer-250Mg Capsule may cause side effects such as nausea, vomiting, abdominal pain, and reddish/brown discolouration of the urine.

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Prescription drug

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Manufacturer/Marketer

Cipla Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Kelfer-250Mg Capsule

Kelfer-250Mg Capsule is indicated to remove excess iron from the body. It is used to treat iron overload caused by frequent blood transfusions in patients with thalassemia syndromes when current chelation therapy is inadequate.

Kelfer-250Mg Capsule contains Deferiprone, which works by attaching to iron and helps your body pass the extra iron out in the urine. Thus, it helps treat iron overload.

In some cases, Kelfer-250Mg Capsule may cause side effects such as nausea, vomiting, abdominal pain, and reddish/brown discolouration of the urine. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

If you are allergic to any components in Kelfer-250Mg Capsule , please inform your doctor. Do not take Kelfer-250Mg Capsule if you are pregnant or breastfeeding. The safety and effectiveness have not been established in children. Keep the doctor informed about your health condition and medications to rule out any side effects.

Uses of Kelfer-250Mg Capsule

Treatment of iron overload

Medicinal Benefits

Kelfer-250Mg Capsule belongs to the group of medicines called iron chelators used to remove excess iron from the body. It is used to treat iron overload caused by frequent blood transfusions in patients with thalassemia syndromes when current chelation therapy is inadequate. Kelfer-250Mg Capsule contains Deferiprone, which works by attaching to iron in the body so that it can be removed from the body. Thus, it helps treat iron overload.

Directions for Use

Take Kelfer-250Mg Capsule with or without food. Take Kelfer-250Mg Capsule with food if you experience nausea, vomiting, or stomach upset. Swallow the medicine as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kelfer-250Mg Capsule

  • Nausea
  • Vomiting
  • Abdominal pain
  • Reddish/brown discolouration of urine
  • Headache
  • Diarrhoea

Drug Warnings

Do not take Kelfer-250Mg Capsule if you are allergic to any of its components, if you have a very low/low blood cell count, or if you are pregnant or breastfeeding. Consult the doctor if you become pregnant during treatment with Kelfer-250Mg Capsule . Stop using Kelfer-250Mg Capsule and consult the doctor immediately if you experience signs of infection like fever, chills, body pain, skin sores, or sore throat. Inform the doctor if you have a weak immune system or liver or kidney disease. Let the doctor know if you are taking any prescription/non-prescription medicines, mineral/vitamin supplements or herbal products.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking immunosuppressants (tocilizumab, everolimus), antacids (sucralfate), or herbal products (milk thistle).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have liver impairment or agranulocytosis/neutropenia (very low/low white blood cell count).

Drug-Drug Interactions Checker List

  • TOCILIZUMAB
  • EVEROLIMUS
  • SUCRALFATE

Habit Forming

No

Diet & Lifestyle Advise

  • Follow a well-balanced diet.
  • Reduce the intake of iron-rich foods like red meat.
  • Donate blood regularly.
  • Avoid using iron cookware.
  • Do not take vitamin C foods that are rich in iron.

Special Advise

  • The doctor may advise regular blood tests to monitor blood count and iron load in the body.
  • Women of childbearing potential must use effective contraception during treatment and for 6 months after the last dose.
  • Men should use effective contraception during treatment and for 3 months after the last dose.

Disease/Condition Glossary

Iron overload: Iron overload is a condition in which the body has too much iron. It usually occurs due to a condition known as hemochromatosis. Excess iron may poison organs and lead to conditions like cancer, liver cirrhosis, and irregular heartbeat. Symptoms may include general weakness, joint pain, fatigue, stomach pain, and weight loss.

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Alcohol

Unsafe

Avoid alcohol consumption while taking Kelfer-250Mg Capsule as it may make the side effects worse.

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Pregnancy

Unsafe

Deferiprone belongs to pregnancy category D. Do not take Kelfer-250Mg Capsule if you are pregnant as it may cause foetal harm.

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Breast Feeding

Unsafe

It is not known if Deferiprone passes into breast milk. Avoid breastfeeding during treatment with Kelfer-250Mg Capsule and for two weeks after the last dose.

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Driving

Safe if prescribed

Kelfer-250Mg Capsule is unlikely to affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

The safety and efficacy of Kelfer-250Mg Capsule in patients with severe liver problems have not been established. Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

The safety and effectiveness of Kelfer-250Mg Capsule in children have not been established.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - KEL0149

Author Details

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FAQs

Kelfer-250Mg Capsule is used to remove excess iron from the body. It is used to treat iron overload caused by frequent blood transfusions in patients with thalassemia syndromes when current chelation therapy is inadequate.
Kelfer-250Mg Capsule works by attaching to iron in the body and facilitating its removal.
Kelfer-250Mg Capsule may cause reddish/brown discolouration of urine. Do not worry, as this is a very common side effect and is not harmful. However, if you have any concerns, talk to your doctor.
Maintain a gap of 4 hours between Kelfer-250Mg Capsule and mineral/vitamin supplements and antacids containing polyvalent cations like iron, aluminium, and zinc.
The common side effects of the Kelfer-250Mg Capsule are nausea, vomiting, abdominal pain, reddish/brown discoloration of urine, headache, diarrhoea. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

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