Kachdex 8 Injection is used to replace Dexamethasone deficiency. It treats various medical conditions, including severe allergic conditions, collagen diseases, pulmonary disorders, blood disorders, rheumatic diseases, skin diseases, gastrointestinal disorders, oedema, eye disorders, neoplastic states and endocrine disorders. It is also used in preoperative and postoperative support. Furthermore, it is approved for the treatment of coronavirus disease 2019 (COVID-19) in adult and adolescent patients (aged 12 years and older with a body weight of at least 40 kg) who require supplemental oxygen therapy.

Kachdex 8 Injection contains dexamethasone, a steroid with both anti-inflammatory and immunosuppressant activity. Anti-inflammatory activity relieves the symptoms of inflammatory conditions, such as redness, swelling, and tenderness caused by various medical conditions. On the other side, immunosuppressant activity helps to calm your immune system. As a result, it can aid in autoimmune diseases such as rheumatoid arthritis, in which your immune system erroneously destroys your own tissues.

Kachdex 8 Injection will be administered by a healthcare professional; do not self-administer. Some people may experience mood changes in personality, mental health problems, muscle weakness, increased appetite, irregular or absent menstrual periods, infections and infestations, impaired vision, difficulty falling asleep or staying asleep, heartburn, peptic ulcer, muscle weakness, nausea and injection site pain or redness as side effects of Kachdex 8 Injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Let your doctor know before prescribing Kachdex 8 Injection if you are allergic to any content of this medicine or sulphites. Inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before receiving this medicine. Before obtaining the Kachdex 8 Injection, notify your doctor about your medical history and any other medications you are currently taking to rule out any potentially harmful effects.

Kachdex 8 Injection is a steroid (corticosteroids) medication. Corticosteroids occur naturally in the body and contribute to overall health and well-being. Increasing your body's corticosteroid levels (such as dexamethasone) is an effective strategy for treating various disorders involving inflammation. Kachdex 8 Injection decreases inflammation, otherwise which might worsen your disease. You must take it daily to get the maximum benefits of Kachdex 8 Injection.

• Difficulty falling asleep or staying asleep

• Mood changes in personality

• Depression

• Muscle weakness

• Increased sweating

• Increased appetite

• Weight gain

• Joint pain

• Irregular or absent menstrual periods

• Injection site pain or redness

• Mental health problems

• Infections and infestations

• Abnormal growth of tissue

• Abnormal increase in the number of white blood cells

• Abnormal hair growth

• Impaired vision

• Vertigo (spinning sensation)

• Headache

• Cataracts or feeling increased pressure in the eye

• Thickening of the heart muscle

• High blood pressure

• Blood clots in the veins

• Nausea

• Hiccups (sudden inspiration or intake of air)

• Heartburn

• Peptic ulcer

• Muscle weakness

• Loss of muscle mass

• Osteoporosis (loss of bone density)

Before prescribing Kachdex 8 Injection, inform your doctor if you are allergic to any content of this medicine or other steroid medicines. You should disclose to your doctor if you have received any live virus vaccines. You should discuss with your doctor if you have fungal infections, amoebiasis, myasthenia gravis, peptic ulcer, osteoporosis, psychoses, eye infections, glaucoma, mental conditions, TB, bacteraemia (viable bacteria in the bloodstream), joint, liver, kidney, or heart conditions and septic arthritis resulting from gonorrhoea or tuberculosis. If you are pregnant, planning for pregnancy or breastfeeding, inform your doctor before receiving this medicine. Contact your doctor immediately if you notice mood changes or have depression and strange thoughts while Kachdex 8 Injection therapy.

Drug-Drug Interactions: Kachdex 8 Injection may interact with nonsteroidal anti-inflammatory drugs (e.g. aspirin), anticonvulsants (e.g. phenytoin), sedative-hypnotic medications (e.g. phenobarbital, primidone), antibiotics (e.g. rifampicin, rifabutin), anticancer (e.g. aminoglutethimide), anticoagulant (e.g. warfarin), antiretroviral drugs (e.g. ritonavir, darunavir), and medicines used to treat epilepsy, pain and manic depression (e.g. carbamazepine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: If you ever had fungal infections, epilepsy, schizophrenia, amoebiasis, myasthenia gravis, peptic ulcer, osteoporosis, psychoses, eye infections, glaucoma, mental conditions, diabetes, TB, bacteraemia (viable bacteria in the bloodstream), joint, liver, kidney, or heart conditions and septic arthritis resulting from gonorrhoea or tuberculosis or have or had a recent vaccination inform your doctor before taking Kachdex 8 Injection.

• ASPIRIN
• PHENYTOIN
• PHENOBARBITAL
• PRIMIDONE
• RIFAMPICIN
• RIFABUTIN
• AMINOGLUTETHIMIDE
• WARFARIN
• RITONAVIR
• DARUNAVIR
• CARBAMAZEPINE

Diet & Lifestyle for Allergic or inflammatory conditions:

• Consume antioxidant-rich food. Blueberries, tomatoes, cherries, squash, and bell peppers are highly antioxidants.

• Consuming probiotic-rich foods aids in the development of the immune system's resistance to allergies.

• Consume foods rich in quercetin (a flavonoid), such as apples, cherries, spinach, broccoli, and blueberries.

• Include seasonal fruits, vegetables, whole grains, healthy fats, and fish in your daily diet.

• Limit your intake of foods that may cause allergies, such as dairy products, soy, eggs, and nuts.

• Limit the consumption of foods high in sugar that may aggravate inflammation.

• Reducing stress and having a regular sleep schedule might be beneficial.

• Avoid processed meats, refined carbohydrates, sugar, trans fats, and alcohol, as they may aggravate inflammation.

Diet & Lifestyle for Covid-19:

• Remember always to wear a mask when you're around other people. Wearing a mask aids in the prevention of illness spread.

• Take care of your mental health. Fear and anxiety can hamper the immune system as well. Therapy, yoga, and meditation effectively allow the mind a state of peace.

• Keep a social distance and avoid social gatherings.

• Please do not touch your eyes, nose or mouth if your hands are not clean.

• Hands should be washed with soap and water or an alcohol-based sanitiser on a regular basis.

• All surfaces should be cleaned and disinfected on a regular basis.

• Gargling with salt water and inhaling steam would be beneficial.

• Never exchange personal objects that have been contaminated with bodily fluids or blood, such as razor blades or toothbrushes.

• Never share used needles and other injections or medical devices, as they may spread viruses.

• Consume a well-balanced diet. Consume vitamin and nutrient-rich foods like dark green, yellow, orange, and red vegetables and fruits to enhance your immune system. Choose lean protein and whole carbohydrates over-processed foods.

• Consume no raw meat or eggs. Consume boiled and cooked meat, poultry, or seafood.

• If you have nausea or vomiting, eat bland, low-fat foods and avoid spicy or greasy foods.

• Spending time with family or doing whatever makes you happy might help you minimise emotional and physical stress.

• Kachdex 8 Injection may affect various laboratory tests. Therefore, inform your doctor/lab technician, that you are on treatment with Kachdex 8 Injection if you are undergoing any tests.

Allergy: Allergy is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as 'allergens.' Allergic condition varies from person to person. Some might be allergic to certain foods, medications, and seasonal allergies like hay fever, pollen, or pet dander. The symptoms of an allergic reaction include itching, rash, scratchy throat, itchy or watery eyes, hives or itchy red spots on the skin, or allergic rhinitis (which causes sneezing or nasal congestion).

Inflammation: It is a response generated by damage to living tissues. This response is a defence mechanism to protect the body from injury, infection, or disease. The symptoms of inflammation include redness, pain, swelling, heat, or loss of function. Inflammation can be caused by certain medications, acute and chronic conditions, exposure to foreign materials or irritants your body can't eliminate easily. 

Coronavirus disease (COVID-19): Covid-19 is an infectious disease caused by the SARS-CoV-2 virus. Most persons who become ill with Covid-19 will have mild to moderate symptoms and recover without specific therapy. Some, though, will become extremely unwell and require medical assistance. The virus can spread from an infected person's mouth or nose in microscopic liquid particles when they cough, sneeze, speak, sing, or breathe. Fever, cough, tiredness, and loss of taste or smell are the most common side effects of Covid-19.