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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Kabilen 5 mg Tablet is used to treat cancers such as multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It contains lenalidomide, which works by stimulating the immune system to attack the cancer cells. It also kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. In some cases, this medicine may cause side effects, such as fatigue, constipation, diarrhoea, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition

LENALIDOMIDE-5MG

Manufacturer/Marketer

Fresenius Kabi Oncology Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Kabilen 5 mg Tablet

Kabilen 5 mg Tablet is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Kabilen 5 mg Tablet is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
 
Kabilen 5 mg Tablet contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Kabilen 5 mg Tablet kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Kabilen 5 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Kabilen 5 mg Tablet if you are pregnant or breastfeeding. Kabilen 5 mg Tablet may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Kabilen 5 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Kabilen 5 mg Tablet must use effective contraception. Inform your doctor regarding your health condition and medications before taking Kabilen 5 mg Tablet to rule out any interactions.

Uses of Kabilen 5 mg Tablet

Treatment of Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Medicinal Benefits

Kabilen 5 mg Tablet belongs to the group of medicines called immunomodulatory agents. Kabilen 5 mg Tablet is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Kabilen 5 mg Tablet works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Kabilen 5 mg Tablet kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Kabilen 5 mg Tablet is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

Directions for Use

Swallow Kabilen 5 mg Tablet as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kabilen 5 mg Tablet

  • Weakness
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Shortness of breath
  • Headache
  • Muscle/bone/back pain
  • Decrease in red blood cell count
  • Fever and flu-like symptoms
  • Decreased appetite
  • Blurred vision
  • Upper respiratory tract infection
  • Dry mouth

Drug Warnings

Do not take Kabilen 5 mg Tablet if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Kabilen 5 mg Tablet if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Kabilen 5 mg Tablet if you are breastfeeding as it is not unknown if it passes into breastmilk. Kabilen 5 mg Tablet may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Kabilen 5 mg Tablet is not recommended for use in children. Avoid consuming alcohol along with Kabilen 5 mg Tablet as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug Interactions

Drug-Drug Interactions: Kabilen 5 mg Tablet may interact with digitalis glycosides (digoxin), blood thinner (warfarin), and hormone (erythropoietin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have anaemia, blood clots, infections, heart, kidney, or liver problems.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • ERYTHROPOIETIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.

  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Special Advise

  • Do not take Kabilen 5 mg Tablet if you are pregnant as it might cause severe birth defects or death of the unborn baby.

  • Male patients taking Kabilen 5 mg Tablet must not donate semen and should use effective contraception during sexual activity even though they have undergone vasectomy.

  • You must not donate blood while taking Kabilen 5 mg Tablet and for 4weeks after discontinuing Kabilen 5 mg Tablet .

  • Kabilen 5 mg Tablet might increase the risk of blood clots. Inform your doctor if you notice any symptoms such as chest pain, shortness of breath, swelling of the arm or leg.

  • Kabilen 5 mg Tablet might cause abnormal/increase in liver test results, inform the person doing the test that you are taking Kabilen 5 mg Tablet .

  • Kabilen 5 mg Tablet might increase/decrease your blood sugar levels. Regularly monitor blood glucose levels while taking Kabilen 5 mg Tablet . Consult your doctor if you are diabetic.

  • Inform your doctor if you have any kidney dysfunction as Kabilen 5 mg Tablet might cause kidney problems.

  • Regular blood tests are advised before and during treatment with Kabilen 5 mg Tablet .

Disease/Condition Glossary

Multiple myeloma: Multiple myeloma is a type of cancer that affects a type of white blood cell called a plasma cell. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections.

Myelodysplastic syndromes: It is a group of disorders that occur due to abnormal functioning of blood cells. Symptoms include shortness of breath, anaemia, fatigue, need for blood transfusion, and risk of infections.

Mantle cell lymphoma: It is a cancer of the lymph tissue where the B-cells or B lymphocytes (a type of white blood cells) grow in an uncontrolled manner and build up in the lymph tissue, blood or bone marrow.

Follicular lymphoma: It is a slow-growing cancer that affects B lymphocytes, a type of white blood cells that help fight infection. In the case of follicular lymphoma, too many B lymphocytes build up in the blood, lymph nodes, bone marrow, and spleen.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Kabilen 5 mg Tablet as it might cause increased dizziness.

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Pregnancy

Unsafe

Kabilen 5 mg Tablet should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Kabilen 5 mg Tablet as it is unknown if Kabilen 5 mg Tablet passes into breastmilk.

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Driving

Unsafe

Kabilen 5 mg Tablet may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Kabilen 5 mg Tablet is not recommended for children below 18years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Echelon Institutional Area Plot No-11, Sector - 32 Gurgaon
Other Info - KAB0038

Author Details

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FAQs

Kabilen 5 mg Tablet is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It is also used to treat a type of myelodysplastic syndrome (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
Kabilen 5 mg Tablet works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.
Do not stop taking Kabilen 5 mg Tablet on your own. You are advised to take Kabilen 5 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Kabilen 5 mg Tablet .
No, it is not safe to father a child while taking Kabilen 5 mg Tablet . Kabilen 5 mg Tablet can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Kabilen 5 mg Tablet and for at least 4weeks after discontinuing Kabilen 5 mg Tablet , even if you have undergone a successful vasectomy. Male patients taking Kabilen 5 mg Tablet must not donate semen whilst taking Kabilen 5 mg Tablet and for 4weeks after discontinuing Kabilen 5 mg Tablet .
Patients taking Kabilen 5 mg Tablet must not donate blood during the treatment with Kabilen 5 mg Tablet and for 1month after discontinuation of Kabilen 5 mg Tablet as the donated blood might be given to pregnant women whose foetus should not be exposed to Kabilen 5 mg Tablet since it causes severe birth defects.
People with multiple myeloma taking Kabilen 5 mg Tablet may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Kabilen 5 mg Tablet for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.
Kabilen 5 mg Tablet might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Kabilen 5 mg Tablet .
You should take Kabilen 5 mg Tablet at the same time every day. You can take the capsules with or without food.
Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Some people treated with Kabilen 5 mg Tablet may rarely get other cancers. Consult your doctor for more details.
Yes, you will need to get regular blood tests while taking Kabilen 5 mg Tablet . Your doctor may suggest taking tests before and during treatment.
Yes, even women with fertility difficulties must take birth control while taking this medication. You must also take a negative pregnancy test 10 to 14 days before treatment and again 24 hours before. You will be tested for pregnancy every 2 to 4 weeks while on Kabilen 5 mg Tablet .
Kabilen 5 mg Tablet contains Lenalidomide as an active ingredient.
Common side effects of Kabilen 5 mg Tablet may include fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you persistently experience any of these side effects.
Kabilen 5 mg Tablet should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.
Avoid breastfeeding while taking Kabilen 5 mg Tablet as it is unknown if Kabilen 5 mg Tablet passes into breastmilk.

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