Ilapil LS Capsule

Ilapil LS Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, indigestion, heartburn and peptic ulcers. Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (esophagus), this causes acidity and heartburn. Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.

Ilapil LS Capsule is a combination of two drugs, namely: Ilaprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Ilaprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the release of a chemical messenger (acetylcholine), which increases the movement of the intestines and stomach, preventing the acid from going towards the food pipe. Both medicines in combination provide relief in acid-related problems.

Take Ilapil LS Capsule as suggested by your doctor. You are advised to take Ilapil LS Capsule for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, nausea, vomiting, gas, dry mouth, dizziness and diarrhea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Ilapil LS Capsule if you have a history of gastrointestinal bleeding or intestinal obstruction. On long term treatment, Ilapil LS Capsule may cause osteoporosis and hypomagnesemia (low magnesium levels). Do not take Ilapil LS Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Ilapil LS Capsule may cause drowsiness and dizziness, so drive only if you are alert. Ilapil LS Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Ilapil LS Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid.

Ilapil LS Capsule is prescribed for the short-term treatment of gastro-oesophageal reflux disease (GERD), acidity, indigestion, heartburn and peptic ulcers in individuals who do not respond well to proton-pump inhibitors (PPIs) alone. This medicine reduces the acid production in the stomach and provides relief in pain associated with acidity and heartburn. However, an individual can increase the effectiveness of the medicine by adopting a healthy lifestyle.

• Gas
• Headache
• Nausea
• Vomiting
• Dry mouth
• Dizziness
• Diarrhoea
• Abdominal pain
• Constipation

Do not take Ilapil LS Capsule if you are allergic to any of its contents. Inform your doctor before taking Ilapil LS Capsule if you have a history of pheochromocytoma (tumor of the adrenal gland), epilepsy, mania, gastrointestinal bleeding, intestinal obstruction or severe kidney and liver impairment. Ilapil LS Capsule may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) on long term treatment. Ilapil LS Capsule causes dizziness and drowsiness, so drive only if you are alert. 

Drug-Drug Interactions: Ilapil LS Capsule may have interaction with medicines such as ketoconazole, itraconazole and posaconazole (used to treat fungal infections) or erlotinib (used for certain types of cancer), warfarin and phenprocoumon (blood thinners), atazanavir (a medicine used to treat HIV-infection), methotrexate (used to treat rheumatoid arthritis, psoriasis and cancer), fluvoxamine (used to treat depression and other psychiatric diseases), rifampicin (used to treat infections) and St John’s wort (Hypericum perforatum) (used to treat mild depression).

Drug-Food Interactions: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

Drug-Disease Interactions: Ilapil LS Capsule may have interactions with gastrointestinal bleeding, intestinal obstruction, pheochromocytoma (tumour of the adrenal gland), epilepsy, mania, Clostridium difficile-associated diarrhea (CDAD), liver disease, bone fractures, hypomagnesemia (low levels of magnesium).

• KETOCONAZOLE
• WARFARIN
• METHOTREXATE
• RIFAMPICIN
• FLUVOXAMINE
• ATAZANAVIR
• POSACONAZOLE
• ITRACONAZOLE

• Eat smaller meals more often.
• Avoid tight-fitting clothes.
• Avoid lying down after eating.
• Maintain a healthy weight by regular exercising.
• Practice relaxation techniques and avoid stress by doing yoga or meditation.
• Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
• Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes break every hour by doing brisk walking or stretching.
• Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

• Take Ilapil LS Capsule 1 hour prior to food.
• Your doctor may advice regular monitoring of bone health, as Ilapil LS Capsule in long term use may lead to bone loss.

Acidity: The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, heartburn and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (esophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn and acidity. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. 

Peptic ulcers: Peptic ulcers are sores that develop on the lining of the stomach and intestine due to erosion of the stomach protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting and indigestion. 

Indigestion: Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea and vomiting.