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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:50 PM IST
Ibidarb 100mcg Injection is used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). It helps to reverse anaemia and reduce the need for blood transfusion. It contains Darbepoetin alfa, which works by providing signals to the bone marrow to make more red blood cells. In chronic kidney disease, when the kidney fails to produce sufficient erythropoietin protein that aids in the formation of red blood cells, this medicine stimulates the production of this protein in the bone marrow. It may cause common side effects such as shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain.
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Consume Type

PARENTERAL

Return Policy

Not Returnable

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About Ibidarb 100mcg Injection

Ibidarb 100mcg Injection belongs to the class of medication called 'blood-forming agent'  primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). Ibidarb 100mcg Injection helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia.

Ibidarb 100mcg Injection contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. Ibidarb 100mcg Injection is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, Ibidarb 100mcg Injection stimulates the production of this protein in the bone marrow. 

Ibidarb 100mcg Injection will be injected by the healthcare provider. Do not self-administer. The most common side effects of Ibidarb 100mcg Injection are shortness of breath,  cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of Ibidarb 100mcg Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to darbepoetin alfa or epoetin alfa, please inform your doctor before taking Ibidarb 100mcg Injection to avoid any complications. Also, mention all the other medications you are taking to affect the way Ibidarb 100mcg Injection works. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be signs that the body has stopped responding to Ibidarb 100mcg Injection. 

Uses of Ibidarb 100mcg Injection

Treatment of Anaemia (in cancer and chronic kidney disease)

Medicinal Benefits

Ibidarb 100mcg Injection is a human-made form of naturally occurring erythropoiesis-stimulating protein or erythropoietin (a hormone produced by the kidney's specialized cells and is responsible for protecting red blood cells against destruction and also stimulates the cells of bone marrow to produce more amount of red blood cells). Deficiency of erythropoietin happens when a person is suffering from chronic kidney diseases, which in turn cause low red blood cells count causing anaemia.  This medicine is primarily indicated for treating anaemia (low red blood cell count) in persons with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer except for bone marrow or blood cells' cancer. Ibidarb 100mcg Injection contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. 

Directions for Use

Ibidarb 100mcg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ibidarb 100mcg Injection

  • Shortness of breath
  • Cough
  • Hypotension (low blood pressure)
  • Headache
  • Body aches
  • Diarrhoea
  • Injection site pain 
  • Abdominal pain (stomach pain) 

 

Drug Warnings

Ibidarb 100mcg Injection can enhance the risk of serious heart problems including heart attack so tell your doctor immediately if you notice shortness of breath, sudden numbness or weakness, chest pain, or trouble speaking or understanding. This medicine may also shorten survival time in some people with certain types of cancer. Inform your doctor before taking Ibidarb 100mcg Injection if you have heart disease, high blood pressure, kidney disease, stroke, heart attack, blood clot, seizure, or latex allergy. Do not take Ibidarb 100mcg Injection if you are pregnant or breastfeeding unless prescribed by the doctor. Ibidarb 100mcg Injection may affect a person's ability to drive as it may cause convulsion during initial days of treatment, so a person taking Ibidarb 100mcg Injection should avoid driving or operating any machine. Ibidarb 100mcg Injection should not be given to children below 12 years of age, as safety and effectiveness have not been established. Avoid consuming alcohol along with Ibidarb 100mcg Injection as it could lead to increased dizziness and sleepiness. 

Drug Interactions

Drug-Drug Interactions: Ibidarb 100mcg Injection may have interaction with other chemotherapy drugs (thalidomide),  immunosuppressant medication (cyclosporine),  antihypertensive medicines (captopril). 

Drug-Food Interactions: Avoid alcohol consumption while taking Ibidarb 100mcg Injection as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: Ibidarb 100mcg Injection may have interactions with disease conditions such as seizures, hemodialysis, hypertension, and thrombotic events
 

Drug-Drug Interactions Checker List

  • THALIDOMIDE
  • CYCLOSPORINE
  • CAPTOPRIL

Habit Forming

No

Diet & Lifestyle Advise

  • Limit the consumption of fluids, salt, potassium, phosphorous, and other electrolytes.
  • Eat a low-protein diet, and get enough calories from the foods if you are losing weight.
  • Eat foods that are high in vitamin B12, iron, and folic acid can fulfil the deficiencies of happed in kidney disease.
  • Include a little number of healthy fats in your diet that give you enough energy to be active during the day; however, try to limit fats that make you fatty. Try to include olive oil, peanut oil, and corn oil into your diet.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Using essential oils for massages can help increase circulation.

Special Advise

  • Certain diagnostic tests like Complete blood count (CBC) can help check the count of red blood cells.
  • Have regular haemoglobin tests to check whether there is an improvement in the level of red blood cells after taking Ibidarb 100mcg Injection or not.

Disease/Condition Glossary

Anaemia: It occurs when the body has a lower amount of red blood cells or haemoglobin than normal haemoglobin (iron-rich the protein responsible for allowing red blood cells to carry more oxygen from the lungs to the rest of the body).  In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia. Symptoms of anaemia in chronic kidney disease include fatigue or tiredness, shortness of breath, ashen skin, weakness, body aches, chest pain, dizziness, fainting, fast or irregular heartbeat, headache, sleep problems, and trouble in concentrating. 

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Ibidarb 100mcg Injection as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking Ibidarb 100mcg Injection if you are pregnant unless prescribed by a doctor as Ibidarb 100mcg Injection is a pregnancy category C drug. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Ibidarb 100mcg Injection; your doctor will decide whether Ibidarb 100mcg Injection can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Ibidarb 100mcg Injection causes convulsions (seizures), especially during the initial months of treatment. So, it is better not to drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Ibidarb 100mcg Injection should not be given to children as the safety and efficacy have not been established.

Country of origin

India

Manufacturer/Marketer address

Scf 421, Ist Floor, Motor Market, Manimajra Chandigarh-160047,India
Other Info - IB50712

Author Details

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FAQs

Ibidarb 100mcg Injection is used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). Ibidarb 100mcg Injection helps to reverse anaemia and reduce the need for blood transfusion.
It is suggested to store the Ibidarb 100mcg Injection in the refrigerator and protect it from light. However, a person should not freeze it.
It is advised to tell your doctor about your medical conditions like heart disease, high blood pressure, kidney disease, a stroke, heart attack, or blood clot, a seizure, a latex allergy to avoid any type of medical condition.
A person who is allergic to any chemical compound present in Ibidarb 100mcg Injection or have uncontrolled/untreated high blood pressure, or ever had pure red cell aplasia (a type of anaemia) caused by using darbepoetin alfa, or epoetin alfa is not allowed to take a name.
Consult your doctor before taking Ibidarb 100mcg Injection if you are pregnant or planning for pregnancy. Your doctor will prescribe Ibidarb 100mcg Injection only if the benefits outweigh the risks.
Ibidarb 100mcg Injection contains a protein "Darbepoetin alfa", which works by providing signals to the bone marrow to make more red blood cells. As in chronic kidney disease, the kidney gets damaged and doesn't filter the blood in the way it should be leading to anemia.
Ibidarb 100mcg Injection may cause side effects such as injection site pain, cough, low blood pressure, headache, diarrhoea, body pains, shortness of breath or stomach pain. If these side effects persist or worsen, please consult your doctor.
After beginning treatment with Ibidarb 100mcg Injection, it takes around 2 to 6 weeks for increase in haemoglobin level in blood.
Ibidarb 100mcg Injection is used only if anaemia is due to chronic (long term) kidney disease and chemotherapy for some types of cancer (except for bone marrow and blood cells).
Ibidarb 100mcg Injection may cause high blood pressure particularly in patients with long term kidney disease due to the rapid increase of red blood cells in the initial 3 months after starting Ibidarb 100mcg Injection.
Ibidarb 100mcg Injection is not used in the treatment of cancer. It is used in treatment of anemia (low levels of healthy red blood cells) in patients receiving chemotherapy for some types of cancer (except for bone marrow or blood cells cancer).
Ibidarb 100mcg Injection should be used with extreme caution as it can cause serious side effects and can even be life-threatening. The patient should follow doctor’s recommendations strictly.
If you have deficiencies of folic acid, vitamin B12 or iron, you may not respond to Ibidarb 100mcg Injection. It is important that you take measures to correct these deficiencies. Other reasons may be infections, bleeding, inflammation and bone marrow fibrosis. If you have any concerns, consult your doctor.
Ibidarb 100mcg Injection is usually not recommended for children as the safety and effectiveness were not established. However, if you have any concerns regarding the use of Ibidarb 100mcg Injection for children, please consult your doctor.

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