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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Histonate Expectorant is used to provide relief from cough. Additionally, it may also help in providing relief from allergies and nasal congestion due to colds. It works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. It helps remove phlegm/mucus from the airways by decreasing its stickiness. Also, it helps reduce congestion, making it easier to cough out phlegm. Thus, it provides relief from cough. Sometimes, you may experience certain common side effects such as headache, stomach upset, dizziness, tiredness, and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Unimerk Pharma Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Histonate Expectorant

Histonate Expectorant is used to provide relief from cough. Additionally, Histonate Expectorant may also help in providing relief from allergies and nasal congestion due to colds. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways, thereby preventing respiratory infection.
 
Histonate Expectorant combines three drugs: Diphenhydramine, Ammonium chloride, and Sodium citrate. Diphenhydramine works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Ammonium chloride helps remove phlegm/mucus from the airways by decreasing its stickiness. Sodium citrate helps reduce congestion, making it easier to cough out through the mouth. Together, Histonate Expectorant provides relief from cough.
 
Take Histonate Expectorant as prescribed. Depending on your medical condition, you are advised to take Histonate Expectorant for as long as your doctor has prescribed it for you. Sometimes, you may experience certain common side effects such as headache, stomach upset, dizziness, tiredness, and dry mouth. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Histonate Expectorant if you are pregnant or breastfeeding. Histonate Expectorant may cause dizziness, so drive only if you are alert. Histonate Expectorant should be given to children only if prescribed by the doctor. Avoid consuming alcohol with Histonate Expectorant as it could lead to increased dizziness. Inform your doctor about all the prescription, non-prescription and herbal medicines you take to rule out any side effects/interactions.

Uses of Histonate Expectorant

Treatment of Cough, Allergies.

Medicinal Benefits

Histonate Expectorant is a combination of three drugs: Diphenhydramine, Ammonium chloride and Sodium citrate. Histonate Expectorant is used to relieve a cough accompanied by cold symptoms such as sore throat, runny nose, watery eyes, and sneezing. Additionally, Histonate Expectorant helps in providing relief from allergies. Diphenhydramine is an antihistamine that works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Ammonium chloride is an expectorant that helps remove phlegm/mucus from the airways by decreasing its stickiness. Sodium citrate is a mucolytic agent that helps loosen the congestion, making it easier to cough out through the mouth. Together, Histonate Expectorant provides relief from cough.

Directions for Use

Histonate Expectorant should be swallowed as a whole with water, do not chew, break or crush the tablet.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Histonate Expectorant

  • Stomach upset
  • Dizziness
  • Sleepiness
  • Dry mouth
  • Headache

Drug Warnings

Do not take Histonate Expectorant if you are allergic to any of its contents. Inform your doctor before taking Histonate Expectorant if you have asthma, prostate problems, narrow-angle glaucoma, stomach or bowel ulcers, glucose-galactose malabsorption, sucrase-isomaltase deficiency, fructose intolerance, kidney or liver problems; if you are taking antidepressants or anti-Parkinson drugs or have taken them in the last 14days. Consult your doctor before taking Histonate Expectorant if you are pregnant, planning for pregnancy or breastfeeding. Histonate Expectorant may cause dizziness, so drive only if you are alert. Avoid consuming alcohol along with Histonate Expectorant as it could lead to increased dizziness.

Drug Interactions

Drug-Drug Interactions: Histonate Expectorant may have interaction with an antidepressant (isocarboxazid, phenelzine, selegiline, tranylcypromine), anti-Parkinson agent (rasagiline).

Drug-Food Interactions: Avoid consumption of alcohol while taking Histonate Expectorant as it might cause increased dizziness. 

Drug-Disease Interactions: Histonate Expectorant may have interactions with asthma, prostate problems, narrow-angle glaucoma, stomach or bowel ulcers, glucose-galactose malabsorption, sucrase-isomaltase deficiency, fructose intolerance, kidney or liver problems.

Drug-Drug Interactions Checker List

  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • TRANYLCYPROMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Gargle with salt water for relief from sore throat.

  • Avoid smoking and consumption of alcohol.

  • Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods. Replace baked foods, fried foods, white bread, white pasta, french fries, sugary desserts and chips with green leafy vegetables.

  • Drink plenty of fluids to avoid a dry throat while you have a cough. It also helps loosen mucus.

  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Special Advise

  • If you have diabetes, please monitor your blood sugar level regularly.

  • It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.

Disease/Condition Glossary

Allergy: Allergy is an immune system response to foreign elements typically not harmful to your body. These foreign elements are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever. At the same time, others might be allergic to pollen or pet dander. One of the symptoms of allergy is cough.

Cough: Coughing is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. Cough can be dry or productive. A productive cough (wet cough) develops sputum (phlegm or mucus) from the lungs. Cough is commonly caused as a response to allergy or viral infection, but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing out thick, solid white mucus, it indicates that you may have a bacterial infection in the airways. Clear or light-coloured mucus indicates allergies or minor infections in the respiratory tract, and yellow or green mucus indicates a respiratory infection.

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Alcohol

Caution

Histonate Expectorant is taken along with Histonate Expectorant may cause excessive drowsiness and sleepiness.

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Pregnancy

Caution

Histonate Expectorant should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Histonate Expectorant .

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Breast Feeding

Caution

Histonate Expectorant should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Histonate Expectorant .

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Driving

Caution

Histonate Expectorant is known to cause drowsiness and dizziness, so driving a car or operating any machinery which requires concentration should not be done.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Histonate Expectorant should be given to children only if prescribed by the doctor.

Country of origin

India

Manufacturer/Marketer address

2, Cloth Market, Block No 10, Basement Floor, Sanjay Place, Agra, Uttar Pradesh
Other Info - HIS0051

Author Details

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FAQs

Histonate Expectorant belongs to a group of medicines called expectorants and cough products used to relieve cough. Also, Histonate Expectorant may help reduce allergies and nasal congestion due to colds.
Histonate Expectorant is a combination drug containing three medicines: Diphenhydramine, Ammonium Chloride and Sodium Citrate. Diphenhydramine blocks a natural substance (histamine) during an allergic reaction. Ammonium chloride decreases mucus stickiness, and sodium citrate being mucolytic, loosens the mucus and makes it easier to cough out. Together it helps relieve allergy symptoms like sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness.
You should not take Histonate Expectorant if you have asthma, as it might worsen your condition and lead to breathing problems.
Do not take Histonate Expectorant if you have breathing problems like asthma, chronic bronchitis, vision problems like glaucoma or difficulty in peeing due to an enlarged prostate gland. Besides this, if you are taking alcohol, peptic ulcer, sleeping pills, or antianxiety pills, immediately stop taking Histonate Expectorant as it might induce drowsiness and dizziness.
Histonate Expectorant is known to cause drowsiness and sleepiness, so it is recommended not to drive a car or operate any machinery which requires concentration. Also, do not consume alcohol as it might increase drowsiness.
The most common side effects of Histonate Expectorant are sleepiness, impaired coordination, stomach pain, dizziness, and thickened respiratory tract secretions. These side effects usually go away during the treatment.
Dry mouth could be a side-effect of Histonate Expectorant . Limiting caffeine intake, avoiding smoking, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

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