HI Five 10mg Tablet belongs to the class of antiulcer medications called 'proton pump inhibitors used to treat peptic ulcers, duodenal ulcers, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus) and dyspepsia. Gastric reflux or hyperacidity occurs when our stomach produces a large amount of digestive acid, irritating the sphincter located at the stomach's tip. Thus, a damaged sphincter leads to the backflow of digestive acid into the food pipe, causing heartburn and ulcer.

HI Five 10mg Tablet contains 'Ilaprazole', which works by blocking the action of the enzyme known as the gastric proton pump responsible for the production of acid. This reduces the amount of acid produced, heals the ulcers and prevents the formation of new ulcers. Thus, HI Five 10mg Tablet prevents symptoms of hyperacidity which includes heartburn and indigestion.

HI Five 10mg Tablet should be taken as prescribed by the doctor. In some cases, you may experience common side effects such as headache, dizziness, diarrhoea, constipation, nausea, vomiting, flatulence (wind), weakness, flu-like symptoms, back pain, aches, infection, difficulty sleeping, cough, sore throat and runny nose. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking HI Five 10mg Tablet if you have a stomach tumour, liver disease or if you are due to have Chromogranin A blood test. In long-term treatment, HI Five 10mg Tablet may cause low magnesium and vitamin B12 levels and increase the risk of bone fractures. Do not take HI Five 10mg Tablet if you are pregnant or breastfeeding. HI Five 10mg Tablet may cause dizziness and sleepiness, so drive only if you are alert. HI Five 10mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol during the treatment as HI Five 10mg Tablet can increase drowsiness and stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side effects.

HI Five 10mg Tablet belongs to a group of antiulcer medicines called proton pump inhibitors. HI Five 10mg Tablet is used to treat duodenal ulcers, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), heartburn and erosive oesophagitis (acid-related damage to the lining of the oesophagus). HI Five 10mg Tablet works by blocking the action of the enzyme known as the gastric proton pump responsible for the production of acid. This reduces the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

• Headache
• Dizziness 
• Diarrhoea 
• Constipation
• Nausea, vomiting, flatulence
• Weakness 
• Flu-like symptoms
• Back pain, aches,
• Infection
• Difficulty sleeping
• Cough, sore throat and runny nose

Do not take HI Five 10mg Tablet if you are allergic to any of its contents. Inform your doctor before taking HI Five 10mg Tablet if you have a stomach tumour, liver disease, or if you are due to have Chromogranin A blood test. In long-term treatment, HI Five 10mg Tablet may cause low magnesium levels and vitamin B12 levels and increase the risk of bone fractures; the doctor may advise regular tests to monitor your condition. Do not take HI Five 10mg Tablet if you are pregnant or breastfeeding. HI Five 10mg Tablet may cause dizziness and sleepiness, so drive only if you are alert. HI Five 10mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol and HI Five 10mg Tablet as it could lead to increased drowsiness and elevate stomach acid production. Prolonged intake of HI Five 10mg Tablet is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions: HI Five 10mg Tablet may have interaction with a pain killer (aspirin, naproxen), osteoporosis medication (ibandronate, etidronic acid, alendronic acid, clodronic acid), antifungal drugs (fluconazole), iron supplements (ferrous sulphate anhydrous),  anti sleeping drugs (dextroamphetamine, amphetamine), anti-cancer drugs (dacomitinib)  and anti-inflammatory drugs (budesonide).

Food-Drug Interactions: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

Drug-Disease Interactions: HI Five 10mg Tablet may interact with kidney disease, liver disease, bone fractures, and hypomagnesemia (low magnesium levels).

• ZOLPIDEM
• DIAZEPAM
• AMITRIPTYLINE
• CYANOCOBALAMIN
• METHOTREXATE
• ITRACONAZOLE
• KETOCONAZOLE
• ATAZANAVIR
• LEVOTHYROXINE SODIUM
• CLOPIDOGREL
• DULOXETINE
• NAPROXEN

• Eat smaller meals more often.
• Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
• Maintain a healthy weight by regular exercising.
• Avoid lying down after eating to prevent acid reflux.
• Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
• Practise relaxation techniques and avoid stress by doing yoga or meditation.
• Avoid foods such as high-fat, spicy chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
• Avoid sitting continuously, as it may trigger acidity. Take a break of 5minutes break every hour by doing brisk walking or stretching.

• Inform your doctor before taking HI Five 10mg Tablet if you are due to have Chromogranin A blood test.
• HI Five 10mg Tablet may cause abnormal blood and liver enzyme values. Inform the person doing the tests that you are taking HI Five 10mg Tablet.
• Long-term use of HI Five 10mg Tablet may cause an increased risk of bone fractures, stomach infections and vitamin B12 deficiency. The doctor may advise regular tests to monitor your condition.

Acid reflux: The stomach is usually protected from the acid by a mucous layer. In some cases, the mucous layer gets eroded due to excess acid production, which leads to complications like acidity, GERD, heartburn and peptic ulcer. Gastroesophageal reflux disease (GERD) is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. A duodenal ulcer is a painful condition followed by the development of sores or ulcers in the duodenum or stomach lining (the first part of the small intestine, i.e., the duodenum).