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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:37 PM IST
Gliozolamide 100mg Tablet is an anti-cancer medicine used in the treatment of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma. This medicine works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Common side effects include loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever.
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Return Policy

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About Gliozolamide 100mg Tablet

Gliozolamide 100mg Tablet belongs to a class of medicines called 'anti-cancer/ antitumor agent', used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. A brain tumour is an uncontrolled and unregulated proliferation of cells in the brain. 

Gliozolamide 100mg Tablet contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Gliozolamide 100mg Tablet prevents tumours from growing.

Take Gliozolamide 100mg Tablet as prescribed. In some cases, Gliozolamide 100mg Tablet may cause loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever. Most of these side effects of Gliozolamide 100mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are allergic to any of the contents. Gliozolamide 100mg Tablet is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Gliozolamide 100mg Tablet if you are pregnant or breastfeeding. Both women and men using Gliozolamide 100mg Tablet should use birth control to avoid pregnancy and fathering a child. It would be best not to drive and/or operate machines that require alertness as Gliozolamide 100mg Tablet may cause tiredness or sleepiness.

Uses of Gliozolamide 100mg Tablet

Treatment of Brain tumour

Medicinal Benefits

Gliozolamide 100mg Tablet belongs to a class of medicines called anti-cancer/antitumor agents used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. It contains Temozolomide which works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Gliozolamide 100mg Tablet prevents tumours from growing.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gliozolamide 100mg Tablet

  • Loss of appetite
  • Difficulty speaking
  • Headache
  • Vomiting
  • Nausea
  • Diarrhoea
  • Constipation
  • Rash
  • Hair loss
  • Tiredness
  • Infections
  • Fever
  • Increased blood sugar
  • Dry skin
  • Swelling
  • Weight loss/gain
  • Frequent urination

Drug Warnings

Gliozolamide 100mg Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Gliozolamide 100mg Tablet. To treat your condition effectually, continue taking Gliozolamide 100mg Tablet for as long as your doctor has prescribed. Do not stop Gliozolamide 100mg Tablet midway under any circumstances without consulting the healthcare professional. Inform your doctor if you have an allergy to any components of Gliozolamide 100mg Tablet. Inform your doctor before taking Gliozolamide 100mg Tablet if you have allergic reactions, infections, lung, renal or hepatic disorders or low blood count (including neutropenia, lymphopenia, thrombocytopenia). Gliozolamide 100mg Tablet is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Gliozolamide 100mg Tablet if you are pregnant or breastfeeding. Both women and men using Gliozolamide 100mg Tablet should use birth control to avoid pregnancy or fathering a child. Do not receive any vaccinations or immunizations without your doctor's approval while taking Gliozolamide 100mg Tablet.

Drug Interactions

Drug-Drug Interactions: Gliozolamide 100mg Tablet interacts with medicines used to treat infections (e.g. adalimumab), medicines used to treat rheumatoid arthritis (e.g. baricitinib, certolizumab, golimumab, infliximab, leflunomide, upadacitinib), medicines used to treat certain cancers (e.g. cladribine), medicines used to treat mental/mood disorders (e.g. clozapine), medicines used to treat multiple sclerosis (e.g. fingolimod, siponimod, teriflunomide),  cholesterol-lowering medications (e.g. lomitapide), and vaccines (e.g. BCG vaccine, influenza virus vaccine, measles virus vaccine, rotavirus vaccine, rubella virus vaccine smallpox vaccine, typhoid vaccine, varicella virus vaccine, yellow fever vaccine, zoster vaccine).

Drug-Food Interactions: Avoid the consumption of alcohol while taking Gliozolamide 100mg Tablet.

Drug-Disease Interactions: Inform your doctor before taking the Gliozolamide 100mg Tablet you are suffering from urticaria or allergic reactions, bleeding disorders, myelosuppression (bone marrow depression), low blood counts, hepatic or renal dysfunction or disorders.

Drug-Drug Interactions Checker List

  • ADALIMUMAB
  • BARICITINIB
  • CERTOLIZUMAB
  • GOLIMUMAB
  • INFLIXIMAB
  • LEFLUNOMIDE
  • UPADACITINIB
  • CLADRIBINE
  • CLOZAPINE
  • FINGOLIMOD
  • SIPONIMOD
  • TERIFLUNOMIDE
  • LOMITAPIDE
  • BCG VACCINE
  • INFLUENZA (LIVE ATTENUATED)
  • MEASLES (LIVE ATTENUATED)
  • ROTAVIRUS VACCINE
  • RUBELLA (LIVE ATTENUATED)
  • SMALLPOX VACCINE
  • TYPHOID VACCINE
  • VARICELLA (LIVE ATTENUATED)
  • YELLOW FEVER VACCINE
  • ZOSTER VACCINE LIVE

Habit Forming

No

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Special Advise

  • Gliozolamide 100mg Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Gliozolamide 100mg Tablet.
  • Your doctor may advise you to get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count.
  • Both male and female patients who are taking Gliozolamide 100mg Tablet must use effective contraceptive precautions. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment. Male patients should avoid fathering a child while on treatment with Gliozolamide 100mg Tablet and should use effective contraception during the treatment and for 3months after the treatment.

Disease/Condition Glossary

Brain tumour: A brain tumour is an uncontrolled, unregulated proliferation of cells in the brain. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. The symptoms of a brain tumour differ depending on the tumour's location in the brain. Common symptoms include headaches, fits (seizures), feeling unwell or being sick all the time, behavioural changes, paralysis, sickness, eyesight or speech impairments.

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Gliozolamide 100mg Tablet. It could lead to unpleasant side effects.

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Pregnancy

Caution

Please consult your doctor if you have any concerns about this. Gliozolamide 100mg Tablet should not be used during pregnancy unless prescribed by your doctor. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment.

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Breast Feeding

Unsafe

Gliozolamide 100mg Tablet should not be taken during breastfeeding as it passes into the breastmilk and may harm the baby.

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Driving

Caution

Gliozolamide 100mg Tablet may make you feel tired or sleepy. Drive and/or operate machines only if you are alert.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before using Gliozolamide 100mg Tablet. Your doctor will weigh the benefits and potential risks before prescribing Gliozolamide 100mg Tablet.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before using Gliozolamide 100mg Tablet. Your doctor will weigh the benefits and potential risks before prescribing Gliozolamide 100mg Tablet.

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Children

Caution

Safety and effectiveness of Gliozolamide 100mg Tablet in paediatric patients under the age of three have not been established.

Manufacturer/Marketer address

Biochem Pharma, Lg 113 / A, Xth Central Mall, Mahavir Nagar, 90Ft Road, Next To D Mart, Kandivali - West, Mumbai - 400067.
Other Info - GL26525

Author Details

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FAQs

Gliozolamide 100mg Tablet belongs to a class of medicines called anti-cancer agents, used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years.
Gliozolamide 100mg Tablet works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Gliozolamide 100mg Tablet prevents tumours from growing.
Gliozolamide 100mg Tablet may cause permanent infertility. Male patients should use effective contraception and refrain from fathering a child for up to three months after treatment is completed. Prior to treatment, it is recommended to seek sperm conservation advice from your doctor.
Yes, Gliozolamide 100mg Tablet can cause neutropenia (low white blood cells count), lymphopenia (low lymphocytes count), thrombocytopenia (low platelet count). As a part of therapy, your doctor may monitor your blood profile.
Gliozolamide 100mg Tablet may lead to hyperglycemia (Increased blood sugar). Consult your doctor if you are diabetic. Regularly monitor your blood sugar levels while taking Gliozolamide 100mg Tablet.
The live vaccine may interact with Gliozolamide 100mg Tablet. Do not have vaccinations or immunisations without talking to your doctor first.

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