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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:16 PM IST
Galen-400 Tablet is an amino acid used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression. This medicine helps in optimal cellular functioning, monitors and regulates important physiological functions, increases glutathione concentration and metabolism of the liver. Common side effects include nausea, diarrhoea, stomach pain, and flatulence.
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Manufacturer/Marketer

Nova Healthcare

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

About Galen-400 Tablet

Galen-400 Tablet is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression. Alcoholic liver disease occurs due to liver damage because of excessive alcohol consumption. Osteoarthritis is a condition in which the joints are affected. Depression is a mood disorder and a psychological, physiological and emotional experience that affects the way we think, the things we do and the way we act. 

Galen-400 Tablet contains S-Adenosyl-L-Methionine disulfate tosylate. It is an essential amino acid required for optimal cellular functioning. Galen-400 Tablet is believed to monitor and regulate important physiological functions in living cells. It increases glutathione concentration and metabolism of the liver. Galen-400 Tablet increases chondrocyte proteoglycan synthesis, thereby helping treat osteoarthritis.

Galen-400 Tablet may be taken with or without food, but it is better to take it at a designated time. In some cases, Galen-400 Tablet may cause certain common side effects such as nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Exercise caution when taking Galen-400 Tablet with any anti-Parkinsonian drugs or anti-depressants. It is not advisable to take alcohol with Galen-400 Tablet as there may be an interaction. Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Uses of Galen-400 Tablet

Treatment of Liver disease, osteoarthritis and depression

Medicinal Benefits

Galen-400 Tablet contains S-Adenosyl-L-Methionine disulfate tosylate. Galen-400 Tablet helps in the synthesis of essential amino acid methionine, which is required for major body functions. It helps provide cellular energy and charge the living cells of various organs like the brain, bones and liver with stamina and fuel, thereby finding application in the treatment of depression, arthritis and liver disease. It helps in major detoxification of the liver in case of diseases caused by a retarded flow of bile such as intrahepatic cholestasis. Galen-400 Tablet also finds use in the treatment of fibromyalgia, attention deficit hyperkinetic disorder and Alzheimer’s disease. However, studies to understand the mechanism behind the same have been inconclusive.

Directions for Use

Take Galen-400 Tablet exactly as directed by the physician. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Galen-400 Tablet

  • Nausea
  • Diarrhoea
  • Flatulence
  • Stomach pain

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of Galen-400 Tablet . Keep your doctor informed of your entire medical history before using Galen-400 Tablet . Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Exercise caution when taking Galen-400 Tablet with any anti-Parkinsonian drugs or anti-depressants. It is not advisable to take Galen-400 Tablet with alcohol as there may be an interaction. Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Drug Interactions

Drug-Drug Interactions: Galen-400 Tablet may interact with antiparkinson drug (levodopa), antidepressants (fluoxetine, paroxetine, citalopram, escitalopram, sertraline, imipramine, clomipramine), antipsychotics (olanzapine, clozapine, risperidone), painkillers (tramadol, methadone, meperidine) and anti-migraine triptans (sumatriptan, zolmitriptan).

Drug-Food Interactions: No interactions were found.

Drug-Disease Interactions: Galen-400 Tablet should be used with caution in patients with a known hypersensitivity disorder, mental health disorder, bipolar disorder and Parkinson’s disease.

Drug-Drug Interactions Checker List

  • FLUOXETINE
  • PAROXETINE
  • SERTRALINE
  • CITALOPRAM
  • ESCITALOPRAM
  • TRAMADOL
  • METHADONE
  • MEPERIDINE
  • SUMATRIPTAN
  • ZOLMITRIPTAN
  • LEVODOPA
  • OLANZAPINE
  • RISPERIDONE
  • CLOMIPRAMINE
  • IMIPRAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Load up on lean meats, fatty fish, green leafy vegetables, fruits and nuts to enhance anti-oxidation and optimal functioning of the body.
  • Drink a lot of water and keep yourself hydrated.
  • Maintain a healthy weight by exercising for at least 30 minutes daily. 
  • Stop smoking as this can have a negative effect on the absorption of Galen-400 Tablet and worsen the disease condition.

Disease/Condition Glossary

Liver disease: Liver disease is a condition in which the liver does not function properly. Symptoms include severe skin itching, nausea, loss of appetite, jaundice, dark urine or stools etc. 

Osteoarthritis: Osteoarthritis is the most common type of arthritis. It occurs due to the breakdown of cartilage that cushions and protects the bones. The disease progresses gradually and tends to worsen if not treated. Symptoms include joint pain in the hips, lower back, knees and hands.

Depression: Depression is a psychological, physiological and emotional experience that affects the way we think, the things we do and the way we act. Losing interest in activities you once enjoyed, loss of appetite, feelings of guilt, low mood, low self-esteem and low energy levels are some symptoms of depression.

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Alcohol

Caution

It is not known whether it is safe to consume alcohol with Galen-400 Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Please consult your doctor before taking Galen-400 Tablet if you are pregnant.

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Breast Feeding

Caution

Please consult your doctor before taking Galen-400 Tablet if you are breastfeeding.

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Driving

Caution

Galen-400 Tablet may rarely cause drowsiness and dizziness. Exercise caution while driving in case of these side effects.

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Liver

Consult your doctor

Galen-400 Tablet is possibly safe on the liver. Please consult your doctor in case of any concerns.

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Kidney

Consult your doctor

Galen-400 Tablet is possibly safe on the kidney. Please consult your doctor in case of any concerns.

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Children

Caution

It is not established if Galen-400 Tablet is safe to use in children. Please consult the treating doctor in case of any concerns.

Country of origin

India

Manufacturer/Marketer address

Al Barsha 1 Dubai United Arab Emirates
Other Info - GAL0193

Author Details

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FAQs

Galen-400 Tablet is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression.
Galen-400 Tablet works by synthesis of methionine, which is an essential amino acid required for cellular energy.
Please see an orthopaedic doctor if you have had a fracture. Galen-400 Tablet is used in the case of arthritis and has limited use in the treatment of fractures as a fracture is more of surgical concern.
Galen-400 Tablet finds a lot of benefit in treating depression. However, consult your doctor before starting Galen-400 Tablet , and if you are on any anti-depressants, keep your doctor informed to avoid any interactions.
In case you miss a dose of Galen-400 Tablet , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.
Galen-400 Tablet is probably safe on the kidney, however, in case of CKD, it is best to consult your treating doctor before using Galen-400 Tablet .
The active ingredient is S-adenosyl-l-methionine disulfate tosylate, an essential amino acid.
Galen-400 Tablet helps keep your liver healthy. It supports liver function, protects liver cells, and reduces inflammation. Galen-400 Tablet also boosts the production of glutathione, a powerful antioxidant that shields the liver. Studies have shown that Galen-400 Tablet may be beneficial for various liver conditions, including fatty liver disease, fibrosis, and hepatitis. However, it's crucial to consult a healthcare professional before taking Galen-400 Tablet , especially if you have a pre-existing liver condition or are taking medications. They will determine the right dosage and ensure safe use.
Common side effects of Galen-400 Tablet may include nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
Informing your doctor about your medical history is crucial for receiving personalized and effective care. Sharing your previous illnesses, surgeries, current medications, allergies, and family medical history helps your doctor understand your overall health and make informed decisions. This includes identifying potential drug interactions, avoiding harmful side effects, and developing an adapted treatment plan that addresses your unique needs.
Don't take Galen-400 Tablet without consulting a doctor. They will help you determine if it's right for you, ensure the correct dosage, and monitor potential interactions with other medications or health conditions. Taking medication on your own can be risky and lead to adverse reactions or worsening of underlying conditions. Always consult a healthcare professional before taking any medication, including Galen-400 Tablet , to ensure your safety and well-being.
Sharing medication with others, even if they have the same problem, is not a good idea. Everyone's body is different; what works for you might not work for someone else. Plus, it can be dangerous and lead to bad reactions or interactions with other medications. Instead, tell the person to see their own doctor so they can get the right treatment and medication for their specific needs. It's always best to prioritize safety and get personalized medical advice!
It is important to exercise caution when driving or riding a bike after taking Galen-400 Tablet . Galen-400 Tablet can cause dizziness, sleepiness, or lightheadedness, impairing your ability to drive safely. For safety, consult your doctor or the medication's label. They might advise you to wait a bit after taking the Galen-400 Tablet or to have someone else drive or ride with you.
The onset of action may vary depending on the individual and the condition being treated.
Consult your doctor before stopping or changing your medication regimen.
It is not established if Galen-400 Tablet is safe to use in children. Please consult the treating doctor if you have any concerns.

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