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Flu-Stim 50 mg Injection 2 ml

Flu-Stim 50 mg Injection 2 ml

Prescription drug
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Synonym

FLUDARABINE PHOSPHATE

Composition

FLUDARABINE-25MG

Manufacturer/Marketer

Zydus Cadila

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-26

for this medicine

About Flu-Stim 50 mg Injection 2 ml

Flu-Stim 50 mg Injection 2 ml belongs to a group of anticancer medicines called purine analogue used in the treatment of chronic lymphocytic leukaemia. Leukaemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. 

Flu-Stim 50 mg Injection 2 ml contains Fludarabine, which works by inhibiting DNA synthesis (responsible for DNA elongation, synthesis, and repair) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes. Thus, Flu-Stim 50 mg Injection 2 ml slows or stops the growth of cancer cells in the body.

Flu-Stim 50 mg Injection 2 ml may cause certain side effects such as fever, chills, hair loss, depression, fatigue, vomiting, nausea, headache, cough, constipation, oedema, weakness, and pain at the site of injection. Most of these side effects of Flu-Stim 50 mg Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer Flu-Stim 50 mg Injection 2 ml. Hence, do not self-administer.

If you are allergic to Flu-Stim 50 mg Injection 2 ml, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Flu-Stim 50 mg Injection 2 ml. Flu-Stim 50 mg Injection 2 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, consult your doctor if you are pregnant, planning to become pregnant or breastfeeding. Let the doctor know if you have/had kidney or liver disease, hemolytic anaemia, severe bone marrow suppression, thrombocytopenia, or neutropenia before starting the treatment, as it may worsen your condition. Inform your doctor if you have received any vaccination before starting the treatment.

Uses of Flu-Stim 50 mg Injection 2 ml

Treatment of Chronic lymphocytic leukemia

Medicinal Benefits

Flu-Stim 50 mg Injection 2 ml contains Fludarabine, which belongs to the class of purine analogues. It works by inhibiting DNA synthesis (responsible for DNA elongation, synthesis, and repair) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes. Thus, Flu-Stim 50 mg Injection 2 ml stops the multiplication of abnormal cells and causes the death of cancer cells.

Directions for Use

An oncology doctor will administer Flu-Stim 50 mg Injection 2 ml. Self-administration is not recommended.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Flu-Stim 50 mg Injection 2 ml

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Constipation
  • Weakness
  • Injection site reactions
  • Pain at the site of injection
  • Headache
  • Hair loss

Drug Warnings

If you are allergic to Flu-Stim 50 mg Injection 2 ml, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Flu-Stim 50 mg Injection 2 ml. Flu-Stim 50 mg Injection 2 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, consult your doctor if you are pregnant, planning to become pregnant or breastfeeding. Let the doctor know if you have/had kidney or liver disease, haemolytic anaemia, severe bone marrow suppression, thrombocytopenia (low number of platelets), or neutropenia (low white blood cells) before starting the treatment, as it may worsen your condition. If you are about to receive any vaccinations, inform your doctor that you are taking Flu-Stim 50 mg Injection 2 ml as it may cause infection.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking vaccines or antimetabolite drugs (pentostatin).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have liver or kidney disease, hemolytic anaemia, severe bone marrow suppression, thrombocytopenia, or neutropenia before starting treatment with Flu-Stim 50 mg Injection 2 ml.

Drug-Drug Interactions Checker List

  • PENTOSTATIN

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking the medication, as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Special Advise

  • Regular blood tests are recommended while receiving Flu-Stim 50 mg Injection 2 ml to monitor any signs of anemia, neutropenia and thrombocytopenia
  • Flu-Stim 50 mg Injection 2 ml is contraindicated for use in combination with pentostatin due to the increased risk of severe pulmonary toxicity.

Disease/Condition Glossary

Chronic lymphocytic leukaemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.

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Alcohol

Caution

It is not known if alcohol interacts with Flu-Stim 50 mg Injection 2 ml. Please consult the doctor.

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Pregnancy

Unsafe

Flu-Stim 50 mg Injection 2 ml is not recommended for use in pregnancy as it may harm the foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Flu-Stim 50 mg Injection 2 ml. You should not become pregnant while on treatment with Flu-Stim 50 mg Injection 2 ml.

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Breast Feeding

Unsafe

Flu-Stim 50 mg Injection 2 ml is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving Flu-Stim 50 mg Injection 2 ml. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Caution

Flu-Stim 50 mg Injection 2 ml will be administered in a hospital setting. Hence, driving is not recommended.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Flu-Stim 50 mg Injection 2 ml.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Flu-Stim 50 mg Injection 2 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

It is unknown whether Flu-Stim 50 mg Injection 2 ml can be given to children or not. Therefore, consult your paediatrician if needed.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad - 380015 Gujarat, India.
Other Info - FLU1053

FAQs

Flu-Stim 50 mg Injection 2 ml is used to treat Chronic lymphocytic leukemia.
Flu-Stim 50 mg Injection 2 ml contains Fludarabine, which works by inhibiting the production of genetic material (DNA) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes.
If you are about to receive any vaccinations, it is advised to inform your doctor that you are on treatment with Flu-Stim 50 mg Injection 2 ml as it may cause infections.
Flu-Stim 50 mg Injection 2 ml may interfere with the normal menstrual cycle in women and may stop sperm production in men. Therefore, please consult a doctor if you plan to have a baby.

Disclaimer

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