Eugraf Gel is used in the treatment of diabetic foot ulcers, bedsores, chronic leg ulcers, and vascular ulcers. A diabetic foot ulcer is an open wound in diabetic patients that occurs due to uncontrolled diabetes. It appears as a red crater on the skin. It mostly affects the bottom or top of the foot and the tip of the toe.

Eugraf Gel contains recombinant human epidermal growth factor, which is a protein that stimulates cell growth. It acts by releasing a growth factor that can promote tissue repair, skin regeneration (formation of healthy skin), and accelerate wound healing. These effects help to reduce skin ulcers in diabetic foot ulcer patients.

Eugraf Gel is meant for external use. Eugraf Gel should be applied as a thin layer with a sterile cotton swab. In some cases, Eugraf Gel may cause certain common side effects such as headache, nausea, rash, stomach pain, and pruritis. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components in Eugraf Gel. Avoid Eugraf Gel if you are immune-compromised, pregnant or breastfeeding. Inform your doctor if you are on treatment with corticosteroids, immunosuppressants or immunostimulators. Keep your doctor informed about your health condition and medications. Discuss your entire vaccination history with your doctor.

Eugraf Gel contains recombinant human epidermal growth factor, an endogenous growth factor that helps in wound healing and new cell production. It is a glycoprotein that binds to epidermal growth factor receptors, enhancing the processes responsible for cellular proliferation, new cell production, collagen synthesis, and reduced cell death, thereby amplifying wound healing and finding major application in the treatment of diabetic foot ulcers, bedsore, chronic leg ulcers and vascular ulcers.

• Headache

• Abdominal pain

• Nausea

• Rash

• Pruritis

It is advisable to inform the doctor if you are allergic to any of the components in Eugraf Gel. Keep your doctor informed if you suffer from hypersensitivity. Avoid Eugraf Gel in case of an immunocompromised state such as HIV. Inform your doctor if you are on treatment with any corticosteroids, or are on any vaccines, immunosuppressants or immunostimulators. Avoid using Eugraf Gel if you are pregnant or breastfeeding.

Drug-Drug Interactions: Inform your doctor if you are using any other medicines.

Drug-Food Interactions: No interactions found.  

Drug-Disease Interactions: Eugraf Gel should be used with caution in patients with a known hypersensitivity disorder and HIV.

• Limit the intake of salt and sugar in your diet. Keep your blood sugar under control.

• Cut back on foods that are high in fat and cholesterol. Eat more fruits, vegetables and whole-grain foods.

• Avoid tobacco use and smoking as this may aggravate your diabetic condition.

• It is important to wear appropriate footwear in case of a diabetic foot ulcer.

• Always use footwear indoors as well.

• Have your toenails cut off regularly by a trained pedicurist.

• Wash and dry your feet at least once every day in lukewarm water, paying special attention to the area between the toes.

Diabetic Foot Ulcer: A diabetic foot ulcer is an open sore or wound seen on the foot of patients suffering from high and uncontrolled blood sugar. It is a painful condition and makes it difficult for them to rest their feet. It is a major complication of diabetes mellitus. It occurs when the diabetes level becomes uncontrollable due to inadequate treatment. In this condition, the skin tissues break down and expose the skin layer's inner parts, which appear as a red crater in the skin. There is also damage to the nerves and decreased blood supply to the damaged foot, which further delays wound healing.