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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:26 PM IST
Etisafe Plus Tablet is used to treat anxiety disorder. It contains Etizolam and Propanolol, which suppresses the excessive and abnormal activity of nerve cells in the brain and reduces blood pressure, heart rate, and workload on the heart. It may cause side effects such as confusion, slow heart rate, memory impairment, tiredness, cold extremities, uncoordinated body movements, and drowsiness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Organic Living Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Etisafe Plus Tablet

Etisafe Plus Tablet is used to treat anxiety disorder. An anxiety disorder is a mental condition characterized by feelings of excessive fear or worry that affect an individual's daily activities. High levels of anxiety can cause panic attacks, with intense feelings of nervousness, fear, sudden onset of sweating, hyperventilation, fast heartbeat, and skin flushing.

Etisafe Plus Tablet contains Etizolam (benzodiazepine) and Propanolol (a beta-blocker), used to treat anxiety. Etizolam works by increasing the action of a chemical messenger, GABA, which suppresses the excessive and abnormal activity of nerve cells in the brain. Propanolol works by blocking a certain chemical messenger in the heart and blood vessels, reducing blood pressure, heart rate, and workload on the heart.

Take Etisafe Plus Tablet as prescribed by your doctor. You are advised to take Etisafe Plus Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience confusion, slow heart rate, memory impairment, tiredness, cold extremities, uncoordinated body movements, and drowsiness. Most of these side effects of Etisafe Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.  

If you are pregnant, planning to become pregnant, or breastfeeding, please inform your doctor Etisafe Plus Tablet contains Etizolam, a habit-forming drug, so take it in dose and duration prescribed by a doctor. Do not stop taking Etisafe Plus Tablet even if you feel better, as it may lead to withdrawal symptoms. Etisafe Plus Tablet is known to cause drowsiness, so do not drive or operate machinery. Avoid consumption of alcohol as it may reduce the effectiveness of Etisafe Plus Tablet.

Uses of Etisafe Plus Tablet

Treatment of Anxiety disorder.

Medicinal Benefits

Etisafe Plus Tablet is a combination drug containing 'anti-anxiety medication', primarily used to treat anxiety disorder. It contains Etizolam (benzodiazepine) and Propanolol (a beta-blocker), used to treat anxiety. Etizolam works by increasing the action of a chemical messenger, GABA, which suppresses the excessive and abnormal activity of nerve cells in the brain. Propanolol works by blocking a certain chemical messenger in the heart and blood vessels, reducing blood pressure, heart rate, and workload on the heart.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Etisafe Plus Tablet

  • Confusion

  • Slow heart rate

  • Memory impairment

  • Tiredness

  • Nightmares

  • Cold extremities

  • Uncoordinated body movements

  • Drowsiness

  • Blurring of vision

  • Loss of appetite

  • Diarrhoea

  • Dry eyes

  • Mood swings

Drug Warnings

Do not take Etisafe Plus Tablet if you are allergic to Etisafe Plus Tablet or any of its ingredients. If you are pregnant or breastfeeding, please inform your doctor before starting Etisafe Plus Tablet as it may cause adverse effects in the baby. Etisafe Plus Tablet should be used with caution in elderly patients as there is an increased risk of adverse reactions such as dizziness, muscle weakness, and drowsiness. Inform your doctor if you have myasthenia gravis (muscle weakness), chronic pulmonary insufficiency, drug addiction, kidney or liver problems before taking Etisafe Plus Tablet. Do not take Etisafe Plus Tablet with opioids as it may cause breathing problems, drowsiness, coma, and even death.

Drug Interactions

Drug-Drug Interaction: Etisafe Plus Tablet may have interaction with high blood pressure-lowering medicines (clonidine, moxonidine, lofexidine, hydralazine, minoxidil, nitroprusside), fits related drugs (phenytoin, clonazepam, alprazolam, escitalopram, carbamazepine), antidepressants (paroxetine, fluvoxamine, trazodone), anti-allergic medication (cetirizine), opioid pain killers (bupropion, morphine, codeine), drugs used to treat heartburn (cisapride), sedative-hypnotics (zolpidem), drugs used to treat low blood sugar (diazoxide), antifungals (fluconazole), drugs for stomach ulcers (cimetidine, esomeprazole, omeprazole), antipsychotics (clozapine), drugs to treat chronic alcoholism (disulfiram).

Drug-Food Interaction: Etisafe Plus Tablet may interact with alcohol. Therefore, avoid alcohol intake while taking Etisafe Plus Tablet as it may increase side effects such as drowsiness, dizziness, or difficulty in concentrating.

Drug-Disease Interaction: If you have myasthenia gravis (muscle weakness), pulmonary insufficiency, kidney or liver problems, diabetes, heart problem, inform your doctor before taking Etisafe Plus Tablet.

Drug-Drug Interactions Checker List

  • CLONIDINE
  • MOXONIDINE
  • LOFEXIDINE
  • HYDRALAZINE
  • MINOXIDIL
  • NITROPRUSSIDE
  • PHENYTOIN
  • CLONAZEPAM
  • ALPRAZOLAM
  • ESCITALOPRAM
  • CARBAMAZEPINE
  • PAROXETINE
  • FLUVOXAMINE
  • TRAZODONE
  • CETIRIZINE
  • BUPROPION
  • MORPHINE
  • CODEINE
  • CISAPRIDE
  • ZOLPIDEM
  • DIAZOXIDE
  • FLUCONAZOLE
  • CIMETIDINE
  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • CLOZAPINE
  • DISULFIRAM

Habit Forming

Yes

Diet & Lifestyle Advise

  • Do regular exercise and maintain healthy body weight.

  • Maintain a diet rich in fruits, vegetables, and whole grains.

  • Avoid fried foods, high-fat dairy products, pastries, and processed foods as they may worsen anxiety.

  • Follow a regular sleep pattern. Do not take a nap during day time.

  • Avoid watching tv, using mobiles or laptops just before bedtime.

  • Avoid consumption of alcohol as it may increase drowsiness

Special Advise

  • Do not take Etisafe Plus Tablet for a prolonged time as it may lead to mental or physical dependence on Etisafe Plus Tablet.

  • Etisafe Plus Tablet causes drowsiness. Avoid doing activities that require your complete focus and attention, like driving when on this drug.

  • An abrupt stoppage of Etisafe Plus Tablet can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.

  • Avoid consuming alcohol while on Etisafe Plus Tablet as it can lead to dangerous side effects.

  • Etisafe Plus Tablet is unsafe for usage if you're pregnant or are planning to get pregnant. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.

  • To avoid getting addicted to this drug, take it only in prescribed quantities and only as directed by your doctor. Do not self-medicate.

Disease/Condition Glossary

Anxiety: High levels of anxiety can cause panic attacks, with intense feelings of nervousness, fear, and sudden onset of sweating, hyperventilation, fast heartbeat, and flushing of the skin. Anxiety disorders are different from feelings of anxiety and feeling nervous, which involve excessive anxiety, fear, or worry. Fear can arise due to anxiety and emotional response to an immediate threat related to more staying to fight or leaving to escape danger. Fear before getting ready for surgery is also a part of short-term anxiety. Anxiety disorders can affect an individual’s job performance, school work, and personal relationships.

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Alcohol

Caution

Avoid consumption of alcohol with Etisafe Plus Tablet as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Caution

Etisafe Plus Tablet is a Category C pregnancy drug, and safety is unknown. Please consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

It is unknown whether Etisafe Plus Tablet is excreted in human milk. Please consult a doctor before using Etisafe Plus Tablet while breastfeeding.

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Driving

Caution

Etisafe Plus Tablet may cause dizziness, double vision, or drowsiness in some people. Therefore, avoid driving if you feel drowsy, dizzy, or experience any vision problems after taking Etisafe Plus Tablet.

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Liver

Caution

Take Etisafe Plus Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Etisafe Plus Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

The safety of Etisafe Plus Tablet in children is unknown. Please consult a doctor for more information.

Country of origin

India

Manufacturer/Marketer address

5E, 1ST FLOOR, RANI JHANSI ROAD, JHANDEWALAN EXTENSION, NEAR VIDEOCON TOWER, NEW DELHI New Delhi DL 110055 IN
Other Info - ETI0071

FAQs

Etisafe Plus Tablet is used to treat anxiety disorder, a mental condition characterized by feelings of excessive fear or worry that affect an individual's daily activities.
Etisafe Plus Tablet contains Etizolam (benzodiazepine) and Propanolol (a beta-blocker), used to treat anxiety. Etizolam works by increasing the action of a chemical messenger GABA, which suppresses the excessive and abnormal activity of nerve cells in the brain. Propanolol works by blocking a certain chemical messenger in the heart and blood vessels, reducing blood pressure, heart rate, and workload on the heart.
No, you are not recommended to stop taking Etisafe Plus Tablet without consulting your doctor as it may cause withdrawal symptoms such as palpitations (the sensation that the heart skipped a beat or extra beat), anxiety, confusion, difficulty in sleeping, and tremors. Therefore, take Etisafe Plus Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Etisafe Plus Tablet, please consult your doctor so that the dose may be gradually reduced.
No, you are not recommended to take Etisafe Plus Tablet with opioids as co-administration of these medicines may cause breathing problems, drowsiness, or other adverse effects. However, before using Etisafe Plus Tablet with any other medicines, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.
Yes, Etisafe Plus Tablet may cause mental or physical dependence if used for a prolonged time. Therefore, take Etisafe Plus Tablet only in dose and duration as advised by your doctor.
Quitting smoking, avoiding alcohol intake, and caffeine-containing food drinks can help you minimize the common side effect. If side effects like exhausted feeling, sleepiness (sedation), muscle weakness, and body posture imbalance persist, it means you need some blood test to find out the exact cause.
No, do not stop taking Etisafe Plus Tablet without consulting your doctor, even if you feel well. Stopping the medication abruptly can lead to withdrawal symptoms or worsening of your condition. Your doctor will advise you on how to taper off the medication safely.
Etisafe Plus Tablet can cause sleepiness or drowsiness as a side effect in some individuals. To ensure your safety, rest for a while after taking the medication and avoid driving or operating heavy machinery. In most cases, sleepiness subsides as your body adjusts to the medication. However, if it worsens or persists, please consult your doctor for guidance.
Store Etisafe Plus Tablet by keeping it cool, dry, and away from sunlight. Keep it out of children's. To dispose of Etisafe Plus Tablet place it in a plastic bag, and discard it in the household trash. Never flush the medicine down the toilet or sink to protect others and the environment.
Some individuals may experience common side effects of Etisafe Plus Tablet including confusion, slow heart rate, memory impairment, tiredness, cold extremities, uncoordinated body movements, and drowsiness. Most of these side effects of Etisafe Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

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