ES Doce 80 Injection Combipack belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

ES Doce 80 Injection Combipack contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

ES Doce 80 Injection Combipack will be administered by a healthcare professional. Your doctor will decide the dosage depending on your medical condition. The common side effects of ES Doce 80 Injection Combipack include pain/swelling at the injection site, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, insomnia (sleeplessness), fever (please inform your doctor if you have fever), muscle aches, and breathlessness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not use or stop this medicine if the doctor did not advise you. Before starting ES Doce 80 Injection Combipack, let your doctor know if you have any allergic reactions, medical history of liver or kidney diseases, heart diseases, blood pressure problems, fits, lung disorders, weak immune system, anemia, low white blood cell count, vision problems, and are receiving chemotherapy. ES Doce 80 Injection Combipack is not indicated for use in pregnant and breastfeeding women. ES Doce 80 Injection Combipack may make you feel dizzy and drowsy, hence do not drive or operate machinery. It is not recommended to consume alcohol along with ES Doce 80 Injection Combipack. ES Doce 80 Injection Combipack is not recommended for children below two years of age.

ES Doce 80 Injection Combipack contains Docetaxel that belongs to the family of anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent and prevents cancer cells from rapidly dividing and spreading. Docetaxel may be used alone or in combination with other chemotherapy drugs to treat breast cancer that has spread to the tissues and lymph nodes (locally advanced breast cancer) and other parts (secondary breast cancer). It is also used in prostate cancer that does not respond to hormone treatment. It is further being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers.

• Pain/swelling at the injection site
• Headache
• Fatigue
• Dizziness
• Drowsiness
• Constipation
• Loss of appetite
• Indigestion
• Tearing of the eyes
• Nausea
• Vomiting
• Diarrhoea
• Insomnia (sleeplessness)
• Fever (please inform your doctor if you have fever)
• Muscle aches
• Breathlessness

Inform your doctor if you have any allergic reactions to ES Doce 80 Injection Combipack or other medications. Before starting ES Doce 80 Injection Combipack, let your doctor know if you have any medical history of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. ES Doce 80 Injection Combipack can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, ES Doce 80 Injection Combipack is not indicated in pregnancy and breastfeeding women. If you are using ES Doce 80 Injection Combipack, use reliable contraception forms to prevent pregnancy during the course. ES Doce 80 Injection Combipack can make you feel dizzy and drowsy, thus affecting your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Avoid alcohol consumption while being treated with ES Doce 80 Injection Combipack. ES Doce 80 Injection Combipack is not recommended for patients younger than 18 years of age.

Drug-Drug Interaction: ES Doce 80 Injection Combipack may interact with antibiotics (itraconazole, erythromycin, rifabutin, metronidazole, tinidazole), HIV drugs (ritonavir), drugs to treat chronic alcoholism (disulfiram), opioid medicines (codeine, hydrocodone), muscle relaxants (carisoprodol, cyclobenzaprine), and anti-allergic medicines (cetirizine, diphenhydramine).

Drug-Food Interaction: Grapefruit and its juice may interact with ES Doce 80 Injection Combipack. Also, avoid alcohol consumption.

Drug-Disease Interaction: ES Doce 80 Injection Combipack should be used with caution in cases of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems.

• ITRACONAZOLE
• ERYTHROMYCIN
• RIFABUTIN
• METRONIDAZOLE
• TINIDAZOLE
• RITONAVIR
• DISULFIRAM
• CODEINE
• HYDROCODONE
• CARISOPRODOL
• CYCLOBENZAPRINE
• CETIRIZINE
• DIPHENHYDRAMINE

• Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains.
• Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
• Include whole grains, legumes, and follow a plant-based diet. Limiting dietary fats is advised during the breast cancer phase. Instead, include healthy fats, such as olive oil, avocado, nuts, seeds, and fatty fish
• Avoid grilled meat, red meat, saturated fat found in animal products, milk, and dairy products.
• Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
• Eat at regular intervals.
• Keep your weight under control with a BMI of 19.5-24.9.
• Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

• Your doctor may advise regular physical exams and mammograms to rule out the possibility of breast cancer.
• Self-examine your breasts to check for any lumps monthly.
• Your doctor may also advise liver function tests to monitor your liver health.
• Your doctor may advise blood tests and regular examinations of the prostate.

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Cancer growth can be prevented by chemotherapy (by strong antibiotics), radiation, and stem cell therapy.

Breast cancer:  It is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue, or the fibrous connective tissue within the breast. Symptoms include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size, or appearance of the breast, and a lump or swelling under the arm.