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Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:44 PM IST

Eptigrilin 20mg Injection is used to treat Myocardial Infarction and Acute Coronary Syndrome. It contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This inhibits fibrinogen binding, reducing the chance of blood clot formation. Eptigrilin 20mg Injection reduces the risk of cardiovascular events like myocardial infarction (heart attack).

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Composition :

EPTIFIBATIDE-20MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Eptigrilin 20mg Injection

Eptigrilin 20mg Injection belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. Eptigrilin 20mg Injection is used in the treatment of Acute coronary syndrome (ACS) in both patients who need to be managed medically and also people undergoing percutaneous coronary intervention (PCI) procedures. ACS is defined as a group of serious cardiac conditions wherein the blood flow to the heart decreases due to plaque formation. Eptigrilin 20mg Injection is also used in the treatment of patients undergoing urgent PCI procedures and also in patients undergoing intracoronary stenting.

Eptigrilin 20mg Injection contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Eptigrilin 20mg Injection reduces the risk of cardiovascular events like myocardial infarction (heart attack).

Eptigrilin 20mg Injection may cause certain side effects, such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, decreased platelet count, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer Eptigrilin 20mg Injection. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Eptigrilin 20mg Injection should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, history of bleeding diathesis within 30 days, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, renal failure, using another glycoprotein IIb/IIIa inhibitor, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, as it can cause serious adverse effects. Eptigrilin 20mg Injection is known to cause bleeding problems. If you observe severe bleeding that cannot be controlled, it is advised to stop administering Eptigrilin 20mg Injection immediately. Hence, close monitoring is needed for any bleeding conditions. Talk to your doctor before receiving Eptigrilin 20mg Injection if you had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before taking Eptigrilin 20mg Injection. Eptigrilin 20mg Injection is not recommended for children below 12 years of age as efficacy and safety have not been established.

Uses of Eptigrilin 20mg Injection

Treatment of Myocardial Infraction and Acute Coronary Syndrome

Medicinal Benefits

Eptigrilin 20mg Injection contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Eptigrilin 20mg Injection results in reducing the risk of cardiovascular events like myocardial infarction (heart attack) and other cardiac events.

Side Effects of Eptigrilin 20mg Injection

  • Bleeding
  • Nausea
  • Headache
  • Abdominal pain
  • Hypotension
  • Vomiting
  • Dizziness
  • Low platelet count
  • Pain at the site of injection

Directions for Use

A trained healthcare professional will administer Eptigrilin 20mg Injection. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not receive Eptigrilin 20mg Injection if you are allergic to it. It is contraindicated in patients who have active internal bleeding, history of bleeding diathesis within 30 days, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, renal failure, using another glycoprotein IIb/IIIa inhibitor, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, as it can cause serious adverse effects. Eptigrilin 20mg Injection is known to cause bleeding problems. However, if you observe severe bleeding that cannot be controlled, it is advised to stop administering Eptigrilin 20mg Injection immediately. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Eptigrilin 20mg Injection if you had a recent severe injury or surgery due to the risk of severe bleeding problems. Before taking Eptigrilin 20mg Injection inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding due to serious foetal harm. Eptigrilin 20mg Injection is not recommended for children below 12 years of age as efficacy and safety have not been established. Talk to your doctor before receiving Eptigrilin 20mg Injection if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems.

Therapeutic Class

ANTIFIBRINOLYTIC AGENTS

Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

How Eptigrilin 20mg Injection Works

Eptigrilin 20mg Injection contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Eptigrilin 20mg Injection reduces the risk of cardiovascular events like myocardial infarction (heart attack).

What if I have taken an overdose of Eptigrilin 20mg Injection

As Eptigrilin 20mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption. Consult your doctor for more information.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Eptigrilin 20mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Eptigrilin 20mg Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Not applicable

Eptigrilin 20mg Injection is used in PCI procedures in a hospital setting. Driving is not recommended.

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Liver

Caution

If you have liver problems, inform your doctor beforehand.

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Kidney

Caution

If you have kidney impairment, inform your doctor beforehand. Eptigrilin 20mg Injection is not recommended for use in patients with renal toxicity.

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Children

Unsafe

Eptigrilin 20mg Injection is not recommended for use in children below 12 years of age, as efficacy and safety have not been established.

Manufacturer/Marketer address

Triton Healthcare Pvt Ltd, Plot No. 75, Natarajan Street, Dhanalakshmi Colony, Vadapalani, Chennai - 600 026.
Other Info - EP52705

Author Details

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FAQs

Eptigrilin 20mg Injection is used to treat Myocardial Infraction and Acute Coronary Syndrome.
Eptigrilin 20mg Injection contains Eptifibatide (anti-glycoprotein IIb/IIIa receptor), which works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation.
Eptigrilin 20mg Injection is known to increase the risk of bleeding. However, if the patient has uncontrollable bleeding, discontinue the medicine immediately.
Eptigrilin 20mg Injection may cause anaemia (low haemoglobin and low red blood cell count). So, it would be best to include iron-rich food in your diet to prevent anaemia.

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