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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 6:05 AM IST

Epidosin 8 Injection 1 ml is used to treat spasms in the intestine and cervix. It contains Valethamate bromide, an anticholinergic drug that works by blocking the effect of acetylcholine (constricts muscle). It dilates the smooth muscles present in the intestine and cervix. Thus, it treats spasms. Common side effects of Epidosin 8 Injection 1 ml are headache, stomach upset, blurred vision, constipation, difficulty swallowing, injection site reactions and irregular heart rate.

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Prescription drug

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Prescription drug
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Synonym

VALETHAMATE

Manufacturer/Marketer

TTK Healthcare Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Epidosin 8 Injection 1 ml

Epidosin 8 Injection 1 ml belongs to the class of medications called ‘antispasmodic agents’ used in the treatment of pain and spasms (muscle contraction) associated with various conditions such as dysmenorrhea (menstrual cramps), postoperative intestinal spasms, gastrointestinal spasm (pain due to muscle straining for expelling gas out of the body), biliary colic (presence of gallbladder stones), and cervical dilation during labour (widening of the cervix to facilitate childbirth).

Epidosin 8 Injection 1 ml contains ‘Valethamate bromide’, an anticholinergic drug that works by blocking the effect of acetylcholine (constricts muscle). It dilates the smooth muscles present in the intestine and cervix. Thus, it treats spasms.

Epidosin 8 Injection 1 ml is a parenteral medicine. It will be administered by a healthcare professional; hence do not self-administer. You may experience certain side effects such as headache, stomach upset, blurred vision, constipation, difficulty swallowing, injection site reactions and irregular heart rate. These side effects usually disappear without any medical attention. However, if any of these side effects persist, talk to your doctor.

Epidosin 8 Injection 1 ml may not be suitable for all. Inform your doctor if you are allergic to it. It should be used with caution if you have liver/kidney problems. Inform your doctor if you have eye problems (glaucoma), prostate gland problems, digestive tract problems, and arrhythmias (irregular heart rate). Avoid driving or operating heavy machinery while on treatment with this medicine, as this medicine may cause vision problems.

Uses of Epidosin 8 Injection 1 ml

Treatment of Spasms of the intestine and cervix

Medicinal Benefits

Epidosin 8 Injection 1 ml contains ‘Valethamate bromide’, which belongs to the class of ‘Spasmolytics or antispasmodic agents. It is an anticholinergic drug that works by blocking the effect of acetylcholine. Acetylcholine is a chemical messenger present in the body that causes spasms or muscle contractions. It dilates the smooth muscles present in the intestine and cervix, thus providing relief from spasms.

Directions for Use

It is administered by a healthcare professional, so do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Epidosin 8 Injection 1 ml

  • Dry mouth

  • Blurred vision

  • Difficulty swallowing or talking

  • Constipation

  • Urinary retention

  • Irregular heart rate

  • Injection site reactions

Drug Warnings

Inform your doctor if you are allergic to Epidosin 8 Injection 1 ml or if you have liver and kidney diseases. If you have eye problems (glaucoma), prostate gland problems, digestive tract problems, and arrhythmias (irregular heart rate), inform your doctor before receiving this injection. Do not drive or operate heavy machinery after receiving Epidosin 8 Injection 1 ml as this medicine may cause vision problems. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking Epidosin 8 Injection 1 ml. 

Drug Interactions

Drug-drug interactions: Epidosin 8 Injection 1 ml may interact with antihistamines, phenothiazides, antipsychotics, and a medication used to treat Parkinson’s disease (a brain disorder). It may antagonize the effects of medications used to treat nausea and vomiting (domperidone and metoclopramide).

Drug-food interactions: No interactions found. 

Drug-disease interactions: Epidosin 8 Injection 1 ml should be used with caution in patients with severe liver and kidney failure, narrow-angle glaucoma (increased pressure inside the eye), enlarged prostate gland, inflammatory conditions of the gastrointestinal system (gut), blockage in the small intestine (pyloric stenosis), and tachyarrhythmia (rapid heart rate).

Drug-Drug Interactions Checker List

  • DOMPERIDONE
  • METOCLOPRAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Regular exercise aids in muscular stretching, making them less prone to spasms, tears, and sprains. Mild workouts like jogging and walking might aid with muscular stretching.

  • Massages can also be helpful.

  • Avoid freezing and hot temperatures. Also, try to avoid wearing tight-fitting clothes; instead, wear loose garments.

  • Rest and sleep well. Always, stay hydrated and drink plenty of water.

  • To avoid developing pressure sores, change your position at least every two hours.

  • Hot or cold therapy can help treat muscle spasms. Apply an ice or hot pack on the muscle for 15-20 minutes.

Special Advise

 

Disease/Condition Glossary

Dysmenorrhea: It is the medical term for menstrual cramps. It occurs due to heavy bleeding or other underlying conditions associated with the uterus.

Urinary colic: It is a condition in which the presence of stones in the kidneys, bladder, ureters, or urethra can block the urinary tract. It causes severe abdominal pain.

Biliary colic: It is a condition in which gallstone blocks the bile duct, which is essential for draining bile from the gallbladder to the small intestine. It results in severe pain in the upper and middle parts of the abdomen.

Cervix Spam: Cervical spam is a sudden involuntary contraction of neck muscles occurring due to strain or weakness. Epidosin 8 Injection 1 ml helps provide relief from cervix spam. It is also used to dilate the cervix during childbirth and help in shortening the labor.

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Alcohol

Caution

Consumption of alcohol may worsen the underlying condition that causes spasms. Hence, avoid alcohol consumption while on treatment with this medicine.

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Pregnancy

Caution

Epidosin 8 Injection 1 ml should be used in pregnancy only if clinically needed. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing this medicine.

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Breast Feeding

Caution

Epidosin 8 Injection 1 ml should be used in breastfeeding only if clinically needed. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing this medicine.

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Driving

Caution

Epidosin 8 Injection 1 ml may cause vision problems. So, do not drive or operate heavy machinery after receiving Epidosin 8 Injection 1 ml until your vision improves.

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Liver

Caution

Epidosin 8 Injection 1 ml should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Epidosin 8 Injection 1 ml to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust the dose based on your condition.

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Children

Consult your doctor

Consult your doctor. Your doctor will weigh the benefits and risks before prescribing this medicine for your child.

Country of origin

India
Other Info - EPI0002

FAQs

Epidosin 8 Injection 1 ml is used to treat Spasms of the intestine and cervix.
Epidosin 8 Injection 1 ml reduces the spasms associated with various conditions. It works by relaxing the smooth muscles by inhibiting the action of acetylcholine (a chemical that causes spasms or muscle contractions).
Epidosin 8 Injection 1 ml does not treat kidney stones. It can only reduce the abdominal pain associated with this condition.
Epidosin 8 Injection 1 ml is a potential fast-acting spasmolytic. It can dilate the cervix during childbirth and help in shortening the labor.
The common side-effects of Epidosin 8 Injection 1 ml are dry mouth, blurred vision, difficulty swallowing or talking, constipation, urinary retention, irregular heart rate and injection site reactions. These side effects usually do not require any medical attention.
As it is a parenteral dosage form, there will be a less or negligible chance of missing a dose. However, if any dose is missed, inform your doctor immediately. But do not self-administer.
Inform your doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or have fits and if you are pregnant, breastfeeding or planning pregnancy. Also, tell your doctor if you are taking any other medicines including herbal products or supplements as Epidosin 8 Injection 1 ml may interact with some medicines. Moreover, let your doctor know if you are stopping any medicine.
Epidosin 8 Injection 1 ml contains Valethamate bromide as its active ingredient.
Epidosin 8 Injection 1 ml will be administered by a doctor or nurse in the clinic or hospital. Do not self-administer.
Epidosin 8 Injection 1 ml is contraindicated in people with benign prostatic hyperplasia (prostate enlargement), narrow angle glaucoma, pyloric stenosis, paralytic ileus (paralysis of intestinal muscles), megacolon, ulcerative colitis (inflammation and ulcers in the lining of the large intestine), tachyarrhythmia (fast heart rate), severe kidney and liver impairment.
Yes, Epidosin 8 Injection 1 ml may interact with other medicines such as antihistamines, phenothiazide antipsychotics, medications used to treat nausea and vomiting (domperidone and metoclopramide) and medicine used to treat Parkinson’s disease. Therefore, let your doctor know about all the medications you are taking.
Store Epidosin 8 Injection 1 ml below 30°C. Protect from light and moisture. Do not freeze. Keep it out of reach of children.

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