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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 9:32 AM IST

Epbriv 0.44 Injection 2 ml is used to treat Breast Cancer and Liposarcoma (cancer that develops in your fatty tissue). It contains Eribulin, which works by stopping the cancer cells from separating into two new cells. So, it blocks the growth of the cancer. It is expected to cause fetal harm when administered to a pregnant woman, so it should not be used in pregnant women. While on therapy with this medicine, both women and men should use birth control to avoid pregnancy. Discontinue nursing while on treatment, considering the importance of the drug to the mother.

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Prescription drug

Whats That

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Synonym :

ERIBULIN

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Epbriv 0.44 Injection 2 ml

Epbriv 0.44 Injection 2 ml belongs to a group of medicines known as 'anti-cancer' used to treat various cancers, including breast and liposarcoma. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. Breast cancer is cancer that forms in the cells of the breasts. A liposarcoma is a rare cancer that develops in your fatty tissue.

Epbriv 0.44 Injection 2 ml contains Eribulin, which works by stopping the cancer cells from separating into two new cells. So, it blocks the growth of the cancer.

Epbriv 0.44 Injection 2 ml should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. The most common adverse reactions that occur while on therapy are neutropenia (lower-than-normal levels of neutrophils), anaemia (lack of blood), asthenia (weakness), fatigue(tiredness), alopecia (hair loss), peripheral neuropathy (Weakness, numbness, and pain from nerve damage), nausea, and constipation. Most of these side effects of Epbriv 0.44 Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

To treat your condition effectually, continue taking Epbriv 0.44 Injection 2 ml for as long as your doctor has prescribed. Do not stop using the Epbriv 0.44 Injection 2 ml midway. It is expected to cause fetal harm when administered to a pregnant woman, so it should not be used in pregnant women. Both women and men using this Epbriv 0.44 Injection 2 ml should use birth control to avoid pregnancy. Discontinue nursing while on therapy, considering the importance of the drug to the mother. Caution should be exercised while using Epbriv 0.44 Injection 2 ml in patients with hepatic, renal, heart dysfunction and or Neutropenia (Lower-than-normal levels of neutrophils), so inform your doctor about all your medical conditions and medications you are currently taking.

Uses of Epbriv 0.44 Injection 2 ml

Treatment of Breast Cancer and Liposarcoma (cancer that develops in your fatty tissue)

Medicinal Benefits

Epbriv 0.44 Injection 2 ml contains Eribulin, which belongs to a group of medicines known as 'anti-cancer' used to treat various types of cancers, including breast and liposarcoma. It works by stopping the cancer cells from separating into two new cells. So, it blocks the growth of the cancer.

Side Effects of Epbriv 0.44 Injection 2 ml

  • Feeling sick (nausea)
  • Being sick
  • Feeling tired or weak (fatigue)
  • Loss of appetite
  • Weight loss
  • Headaches
  • Diarrhoea
  • Constipation
  • Pain in different parts of your body
  • Neutropenia (lower-than-normal levels of neutrophils)
  • Anemia (lack of blood)
  • Asthenia (weakness)
  • Alopecia (hair loss)
  • Peripheral neuropathy (weakness, numbness, and pain from nerve damage)

Directions for Use

Epbriv 0.44 Injection 2 ml should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking the Epbriv 0.44 Injection 2 ml, let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Before taking Epbriv 0.44 Injection 2 ml, inform your doctor about your medical history and other medications you are currently taking in order to rule out any potential negative effects. Epbriv 0.44 Injection 2 ml may cause permanent fertility problems in men if they take it. Please discuss this with their doctor before starting treatment. Women of childbearing age should use effective contraception during and up to 3 months after treatment with Epbriv 0.44 Injection 2 ml. Avoid the consumption of alcoholic beverages and grapefruit juices.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

verifiedApollotooltip
EribulinChloroquine
Severe
EribulinCeritinib
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

How Epbriv 0.44 Injection 2 ml Works

Epbriv 0.44 Injection 2 ml contains Eribulin, which works by stopping the cancer cells from separating into two new cells. So, it blocks the growth of the cancer.

What if I have taken an overdose of Epbriv 0.44 Injection 2 ml

As Epbriv 0.44 Injection 2 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Epbriv 0.44 Injection 2 ml may cause sore throat, cough, fever, chills, burning or pain when urinating, or other signs of infection.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Epbriv 0.44 Injection 2 ml.

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Pregnancy

Unsafe

Epbriv 0.44 Injection 2 ml should not be used during pregnancy because it can harm your fetus (newborn baby).

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Breast Feeding

Unsafe

Do not breastfeed during this treatment because the medicine may pass into your milk. Doctors normally advise against breastfeeding throughout this treatment and for a certain period of time after the final medication is taken.

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Driving

Caution

Epbriv 0.44 Injection 2 ml may cause side effects such as tiredness and dizziness. Do not drive or use machines if you feel tired or dizzy.

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Liver

Caution

A lower starting dose is recommended for patients with mild (Child-Pugh A) and moderate (ChildPugh B) liver impairment. There is no information available on patients with severe liver impairment.

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Kidney

Caution

A lower starting dose is recommended for patients with moderate (CrCl 30-50 mL/min) kidney impairment. There is no information available on patients with severe kidney impairment.

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Children

Unsafe

Do not use this medicine for children between 0 to 18 years old.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - EPB0001

Author Details

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FAQs

Epbriv 0.44 Injection 2 ml is used to treat Renal Cell Carcinoma.
Epbriv 0.44 Injection 2 ml contains Eribulin, an anti-cancer medication that is used to treat several types of cancers, such as breast cancer and liposarcoma. It works by preventing the cancer cells from dividing into two new cells. As a result, it prevents cancer from spreading.
It is recommended not to be used in the population who are allergic to Eribulin or any other ingredients in this medication, is a pregnant woman, has too low blood cell counts, or suffers from severe liver or hepatic impairment.
Yes, Epbriv 0.44 Injection 2 ml can cause low neutrophils levels, a type of white blood cells that help fight infections. Your doctor will monitor peripheral blood cell counts and adjust the dose as appropriate.
Inform your doctor before receiving the Epbriv 0.44 Injection 2 ml if you suffer from QT Prolongation. Your doctor will monitor for prolonged QT intervals in patients with congestive heart failure, bradyarrhythmias, and electrolyte abnormalities. It is recommended not to be used in patients with congenital long QT syndrome.
Epbriv 0.44 Injection 2 ml may cause permanent fertility problems in men if they take it. Please discuss this with their doctor before starting treatment.
Epbriv 0.44 Injection 2 ml may cause hair loss as a common side effect. It is typically temporary and reversible once treatment is completed. However, the extent and duration of hair regrowth can vary from person to person. It is important to discuss any concerns with the doctor, as they can provide guidance based on your specific situation.
The duration of treatment with Epbriv 0.44 Injection 2 ml can be determined by the doctor based on your medical condition being treated. Always follow the doctor’s instructions regarding the duration of treatment and ensure regular follow-ups to treat the condition effectively.
Epbriv 0.44 Injection 2 ml be administered intravenously (IV) for 2 to 5 minutes by the doctor or nurse. Do not self-administer.
It is recommended to wait at least 3 months after completing treatment with Epbriv 0.44 Injection 2 ml before planning a pregnancy. This is because the medication may affect fertility and it may affect foetal development. Always consult the doctor for personalised advice and to ensure it is safe for you to conceive.
It is important to wear protective gloves to avoid direct contact while handling Epbriv 0.44 Injection 2 ml. The used needles and syringes should be disposed of in a proper medical waste container to prevent needle-stick injuries. You should avoid contact with the eyes or skin, if accidental exposure occurs, rinse it off thoroughly with plenty of water and seek medical attention if necessary. Always consult the doctor for specific handling instructions.
The side effects of Epbriv 0.44 Injection 2 ml include nausea, constipation, alopecia (hair loss), neutropenia (lower-than-normal levels of neutrophils), anaemia (lack of blood), asthenia (weakness), fatigue (tiredness), and peripheral neuropathy (Weakness, numbness, and pain from nerve damage). Consult the doctor if any of these side effects persist or worsen. The serious side effects of Epbriv 0.44 Injection 2 ml include cough, sore throat, fever (temperature greater than 100.5), chills, burning or pain when urinating, or other signs of infection numbness, burning, or tingling in the arms, legs, hands, or feet pale skin shortness of breath irregular heartbeat. Consult the doctor immediately if you experience any of these symptoms.
Epbriv 0.44 Injection 2 ml should be diluted with 0.9% sodium chloride injection or dextrose 5% injection before administration, as recommended by the manufacturer. The dilution helps to ensure the correct concentration and allows for the safe administration of the medication. Always follow the specific instructions provided by the doctor or the manufacturer's guidelines when preparing and administering the injection.

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