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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:48 PM IST
Enzochlor 5mg/12.5mg Tablet is used to treat high blood pressure, heart failure, and oedema. It contains Chlorothiazide and Amlodipine which work by reducing excess fluid levels in the body, relaxing and widening the blood vessels, and improving blood flow. This medicine may sometimes cause side effects such as sleepiness, headache, flushing, tiredness, nausea, and decreased potassium levels in the blood. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Druto Laboratories

Consume Type :

ORAL

Return Policy :

Not Returnable

About Enzochlor 5mg/12.5mg Tablet

Enzochlor 5mg/12.5mg Tablet is an anti-hypertensive medicine used to treat high blood pressure, heart failure, and oedema (a buildup of fluid in the body). Hypertension or high blood pressure is a lifelong or chronic condition in which the force exerted by the blood against the blood vessel (artery wall) increases. The higher this blood pressure, the harder the heart has to pump. Edema may occur in cases of high blood pressure where fluids of the body get trapped in the tissues of the hands, arms, feet, ankles, and legs, leading to swelling.

Enzochlor 5mg/12.5mg Tablet contains Chlorothiazide and Amlodipine. Chlorothiazide is a diuretic that increases the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats Edema (swelling) associated with heart, liver, kidney or lung disease. Amlodipine is a calcium channel blocker and works by relaxing and widening the blood vessels. This, in turn, reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. So, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Take Enzochlor 5mg/12.5mg Tablet as prescribed by your doctor. You are advised to take Enzochlor 5mg/12.5mg Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache, (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, Increased blood uric acid and altered blood lipid level. Most of these side effects of Enzochlor 5mg/12.5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Tell your doctor about this, as it may cause a rise in blood pressure and can increase the risk of heart complications like stroke and heart disease. Inform your doctor if you are suffering from any kidney or liver, or heart disease or are diabetic. Taking Enzochlor 5mg/12.5mg Tablet during pregnancy may cause side effects like jaundice (yellowing of the skin or eyes), unexplained bleeding, low blood sugar or an electrolyte imbalance in the newborn baby. Do not use Enzochlor 5mg/12.5mg Tablet if you cannot urinate, have low blood pressure (hypotension), or cardiogenic shock (sudden stopping blood flow to the heart). Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Uses of Enzochlor 5mg/12.5mg Tablet

Treatment of Hypertension (high blood pressure) and oedema (swelling due to fluid retention).

Medicinal Benefits

Enzochlor 5mg/12.5mg Tablet is a combination drug used to treat hypertension. When you take Enzochlor 5mg/12.5mg Tablet, your body's blood vessels will be relaxed, and it will help lower the raised blood pressure. It also widens the blood vessels (lining of arteries wall) and improves blood flow. It helps in losing excess fluids from the body by increasing the production of urine. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. Enzochlor 5mg/12.5mg Tablet also helps decrease fluid buildup, which reduces inflammation or swelling. In addition, this relieves Edema and helps you carry out your daily activities more efficiently.

Side Effects of Enzochlor 5mg/12.5mg Tablet

  • Glucose intolerance (low or high level of glucose)
  • Ankle swelling
  • Sleepiness
  • Headache (sense of heat in the face, ears, neck, and trunk)
  • Flushing
  • Tiredness
  • Decreased potassium level in the blood
  • Increased blood uric acid
  • Altered blood lipid level

Directions for Use

Swallow the whole tablet with approximately a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Enzochlor 5mg/12.5mg Tablet should not be given to the people allergic to Enzochlor 5mg/12.5mg Tablet, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, gout (high uric acid), high cholesterol (hyperlipidemia), pregnant women or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in people with cardiogenic shock (sudden stopping of blood flow to the heart) and aortic stenosis (heart valve problem). Enzochlor 5mg/12.5mg Tablet can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Enzochlor 5mg/12.5mg Tablet and breastfeeding. Tell your doctor if you are on low sodium (table salt) diet. Cases of electrolyte imbalance have been observed (like low levels of sodium, potassium, or magnesium in your blood). So your doctor might advise monitoring blood pressure, kidney function tests and electrolytes.

Therapeutic Class

ANTIHYPOTENSIVES

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
chlorthalidoneCisapride
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.

  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.

  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress, as it can raise your blood pressure. 

  • Monitor your blood pressure daily and if there is too much fluctuation, immediately contact your doctor.

  • Try to include heart-healthy omega-3 fatty acids-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help lower your elevated blood pressure.

Habit Forming

No

How Enzochlor 5mg/12.5mg Tablet Works

Enzochlor 5mg/12.5mg Tablet contains Chlorothiazide and Amlodipine. Chlorothiazide is a diuretic that increases the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats Edema (swelling) associated with heart, liver, kidney or lung disease. Amlodipine is a calcium channel blocker and works by relaxing and widening the blood vessels. This, in turn, reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. So, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

What if I have taken an overdose of Enzochlor 5mg/12.5mg Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.
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Alcohol

Caution

You are recommended not to consume alcohol along with Enzochlor 5mg/12.5mg Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Enzochlor 5mg/12.5mg Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Enzochlor 5mg/12.5mg Tablet should not be used when breastfeeding unless necessary. Your doctor will weigh the benefits and any potential risks before prescribing. Please consult your doctor.

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Driving

Unsafe

It is not recommended to drive after taking Enzochlor 5mg/12.5mg Tablet as it may occasionally cause drowsiness.

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Liver

Caution

Enzochlor 5mg/12.5mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose if required based on your condition.

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Kidney

Caution

Enzochlor 5mg/12.5mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Caution

Enzochlor 5mg/12.5mg Tablet to be taken with caution, especially if you are children below 12. Your doctor will decide the dose based on the age and condition of your child.

Country of origin

India
Other Info - EN10691

Author Details

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FAQs

Enzochlor 5mg/12.5mg Tablet is used to treat high blood pressure, heart failure, and oedema (a buildup of fluid in the body).
Enzochlor 5mg/12.5mg Tablet contains Chlorothiazide and Amlodipine. Chlorothiazide works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats Edema (swelling) associated with heart, liver, kidney or lung disease. Amlodipine works by relaxing and widening the blood vessels. This, in turn, reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body.
It's unlikely that Enzochlor 5mg/12.5mg Tablet affects fertility in men or women. However, some water pills like hydrochlorothiazide may lead to erectile dysfunction. There's not enough evidence to say for certain. For the best advice, consult your doctor.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
Enzochlor 5mg/12.5mg Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.

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