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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:20 PM IST

Endonac Sp Tablet is used to reduce pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. It works by blocking the action of an enzyme known as cyclo-oxygenase (COX), which causes pain and swelling in the injured or damaged tissue. Also, it helps in the breakdown of a protein (fibrin) which is formed as a by-product of the blood clot at the site of injury. Thus, it causes thinning of the fluids around the injury site, thereby making fluid drainage smoother in the swollen tissue. It may cause common side effects such as nausea, vomiting, indigestion, stomach pain, etc. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Endocard India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Endonac Sp Tablet

Endonac Sp Tablet belongs to the class of drugs known as 'non-steroidal anti-inflammatory drugs' (NSAID). It is a fixed-dose combination composed of aceclofenac, paracetamol and serratiopeptidase. Endonac Sp Tablet is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX), which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of aceclofenac. Serratiopeptidase is an enzyme which helps in the breakdown of a protein (fibrin) which is formed as a by-product of the clotted blood at the site of injury. It thus causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue.

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone or organs. Chronic pain lasts for life and is caused by nerve damage, osteoarthritis and dental pain due to damage to the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal. 

You can take Endonac Sp Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your tablets based on your medical condition.  Most of the side effects of Endonac Sp Tablet do not require medical attention and gradually resolve over time. Common side effects include nausea, vomiting, indigestion, stomach pain, etc. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take Endonac Sp Tablet if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Endonac Sp Tablet

Treatment of Pain after any injury, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis, etc.

Medicinal Benefits

Endonac Sp Tablet consists of aceclofenac, paracetamol and serratiopeptidase. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX), which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of aceclofenac. Serratiopeptidase causes thinning of the fluids around the site of injury, thereby making fluid drainage smoother in the swollen tissue. Together, these not only reduce pain and inflammation but also help with faster healing.

Side Effects of Endonac Sp Tablet

  • Nausea
  • Stomach Pain
  • Loss of appetite
  • Diarrhoea
  • Stomach upset
  • Indigestion

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Endonac Sp Tablet as it may lead to an increase in the risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure and liver or kidney disease should not take Endonac Sp Tablet on their own. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to painkillers like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Endonac Sp Tablet . Use with caution in pregnancy and breastfeeding. Do not self-administer Endonac Sp Tablet if you are pregnant or are nursing.

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
ParacetamolKetoconazole
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In the chronic conditions of arthritis or joint pain try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit as little as possible, and only for short time (10-15 min). Use back support like rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

What if I have taken an overdose of Endonac Sp Tablet

Do not take more than the prescribed dose of Endonac Sp Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Endonac Sp Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Endonac Sp Tablet to be taken with caution, specially if you are pregnant. Your doctor may adjust your dose depending upon your conditions, if he/she feels the benefits over weigh the risks.

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Breast Feeding

Caution

Only consume Endonac Sp Tablet if it has been prescribed by a doctor as the safety data in nursing mothers is lacking. Inform your doctor if you are breastfeeding.

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Driving

Caution

Endonac Sp Tablet may affect driving as it causes dizziness.

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Liver

Caution

Endonac Sp Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Endonac Sp Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Endonac Sp Tablet should not be given to children without prescription of a child specialist. Your doctor will determine the dose of the medicine depending on your child's weight and severity of condition.

Country of origin

INDIA

Manufacturer/Marketer address

205 Blue Star PlazaSarja Market, 2nd Floor Sector-7 Rohini East New Delhi-110065
Other Info - END0211

Author Details

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FAQs

Endonac Sp Tablet is used to relieve pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. It is used in the treatment of pain after any injury, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis, etc.
Yes, in most of the patients it is safe to take Endonac Sp Tablet but if it causes any unwanted side effects like diarrhea, vomiting, nausea, please consult your doctor immediately.
Endonac Sp Tablet when taken by patients who are allergic to pain-killers or NSAIDs can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease and stomach ulcers,
A chronic inflammatory disorder affecting many joints, including those in the hands and feet. In rheumatoid arthritis, the body's immune system attacks its own tissue, including joints. In severe cases, it attacks internal organs. Rheumatoid arthritis affects joint linings, causing painful swelling.
Ankylosing spondylitis (AS) is a rare type of arthritis that causes pain and stiffness in your spine. This lifelong condition, also known as Bechterew disease, usually starts in your lower back. It can spread up to your neck or damage joints in other parts of your body.
No. Endonac Sp Tablet is not indicated for stomach pain. If you have stomach pain refer to doctor as it may be sign of stomach ulcer or gastric bleeding.
Taking excessive alcohol with Endonac Sp Tablet can cause liver damage. So, it is advisable to avoid or limit intake of alcohol during the treatment with Endonac Sp Tablet .
Yes. But ensure pain killers or any other drugs you are taking does not contain paracetamol, aceclofenac or serratiopeptidase. As, it may lead to overdosage leading to unpleasant side effects. Always consult your doctor before using other medication.
Long-term usage of Endonac Sp Tablet may result in adverse effects; thus, your health should be monitored frequently. It is best to consult your doctor if you are having problems or if your body is not responding to the Endonac Sp Tablet . Depending on your health, doctor may advise you to undergo tests. They can provide you with specific guidance and help you manage any potential side effects successfully.
Endonac Sp Tablet is not an antibiotic mediation. It is a nonsteroidal anti-inflammatory medication (NSAID) that is used to treat pain and inflammation. Endonac Sp Tablet does not have antibacterial properties like antibiotics do.
Endonac Sp Tablet can be used to relieve pain and inflammation; therefore, it may help with temporary period pain relief. It is important to talk to your gynaecologist before using the Endonac Sp Tablet to treat menstruation cramps. Your gynaecologist can determine if this Endonac Sp Tablet is acceptable for you and recommend the proper dosage based on your medical conditions.
Endonac Sp Tablet can be used to relieve pain and inflammation; therefore, it may help with toothache. Talking to your dentist before using the Endonac Sp Tablet to treat your toothache is important. Your doctor can determine the actual reason for your toothache if this Endonac Sp Tablet is acceptable to you, and the dentist may recommend the proper dosage and usage.
Yes, Endonac Sp Tablet is a painkiller. It belongs to the class of drugs known as ''nonsteroidal anti-inflammatory drugs'' (NSAIDs) that help to reduce pain and inflammation.
Combiflam and Endonac Sp Tablet are pain relievers, but their ingredients and uses differ. Combiflam is better for general pain and fever, while Endonac Sp Tablet is more effective for musculoskeletal pain, inflammation, and swelling. If you have severe pain or inflammation, Endonac Sp Tablet might be a better choice. However, if you have stomach issues or bleeding, Combiflam might be a safer option. Consult your doctor to determine which medication is best for your specific condition and needs. They will assess your individual situation and provide personalized guidance.
Endonac Sp Tablet and Enzoflam are two different pain relievers with some similarities but also a key difference. Both medications have paracetamol and serratiopeptidase, which help relieve pain and reduce inflammation. However, Endonac Sp Tablet contains aceclofenac, while Enzoflam contains diclofenac. This difference in ingredients means that your doctor will choose the best one for you based on your specific needs and medical history.
If you are experiencing lower back pain, Endonac Sp Tablet might be an option to consider. This medication combines three active ingredients to help relieve muscle and joint pain. However, consulting with your healthcare provider before starting any new medication is crucial. They will evaluate your specific condition, medical history, and other factors to determine the best course of treatment and ensure your safety.
If you have diabetes, consult your doctor before taking Endonac Sp Tablet . This medication may impact blood sugar control, kidney function, and gastrointestinal health. Your doctor will help you weigh the benefits and risks and monitor you closely to ensure your safety.
Endonac Sp Tablet is not usually used to treat piles. Instead, it's primarily designed to relieve pain in conditions like muscle aches, joint pain, and post-surgery pain. If you are experiencing piles, it's best to consult your doctor for a medication specifically targeting this condition. They can recommend a more appropriate treatment option for you.
Endonac Sp Tablet recommended to take with food to minimize stomach upset or it may irritate the stomach, so taking them with food helps reduce nausea, vomiting, and stomach ulcers and also helps in enhancing absorption. Consult your doctor or pharmacist for specific guidance on taking this medication.
Take Endonac Sp Tablet only as directed by your doctor or the product label. Usually, this means taking it every 8-12 hours as needed, but follow the specific instructions given to you.
Endonac Sp Tablet and Zerodol are similar medications but differ in one key ingredient: Serratiopeptidase. Endonac Sp Tablet contains Serratiopeptidase, while Zerodol does not. This difference in formulation may affect how the medications work for you, so it is essential to consult your doctor to determine which one is best for your needs.
Endonac Sp Tablet is primarily used to relieve pain and inflammation, but it can also be used to reduce fever. However, it is not typically the first choice for treating fever alone. If you have a fever, your doctor may recommend a different medication, such as acetaminophen (Tylenol) or ibuprofen (Advil, Motrin), depending on the cause and severity of the fever. Always consult your doctor for proper diagnosis and treatment.
Take Endonac Sp Tablet as directed: one tablet every 8-12 hours as needed. Don't take two at once, as this can cause serious side effects. If you need more pain relief, ask your doctor about alternative options. Follow the instructions on the label or your doctor's advice to use Endonac Sp Tablet safely.
Endonac Sp Tablet is not recommended for heart patients because it contains an NSAID, which can increase the risk of heart-related side effects, such as heart attack or stroke, especially with long-term use. If you have a heart condition, consult your doctor before taking Endonac Sp Tablet . They will assess your individual situation and provide personalized guidance on safe treatment options.
Endonac Sp Tablet may not help you with throat pain as its composition consists of anti-inflammatory and pain relievers for muscle, joint, or surgical pain. It's best to consult your doctor for a medication that is specifically designed to address this throat pain issue.
Endonac Sp Tablet is a pain reliever, but it's not for chest pain. If you have chest pain, get medical help right away. It could be a sign of a severe condition like a heart attack. Endonac Sp Tablet might help with mild to moderate pain, but it's not enough for chest pain. If you have chest pain, call emergency services or go to the emergency room. Don't wait!
Endonac Sp Tablet belongs to the class of drugs known as ''nonsteroidal anti-inflammatory drugs'' (NSAID). It is a fixed-dose combination composed of aceclofenac, paracetamol, and serratiopeptidase. It reduces pain and inflammation due to bone or soft tissue injury, resolves postoperative inflammation, and relieves oedema (swollen tissue with fluid).
No, don't stop Endonac Sp Tablet -taking suddenly; there can be sudden negative consequences. If you are relieved by your pain, consult with your doctor first. Your doctor will provide you with guidance by examining your health status in detail to decide whether it is safe to stop or continue for some period for complete relief of your issue.
Nausea and vomiting are the most common side effects people may experience while using this Endonac Sp Tablet . These symptoms will go away with time. If they worsen or persist, consult your doctor.
Dizziness is one of the most common side effects of Endonac Sp Tablet . So, caution should be taken while driving a car or bike.
Taking Endonac Sp Tablet is not recommended if you have allergies to any ingredient, severe liver or kidney disease, stomach bleeding, heart failure, or coronary artery disease. Additionally, pregnant or breastfeeding women should avoid it. If you have mild to moderate liver or kidney issues, a history of stomach ulcers, high blood pressure, heart disease, asthma, or bleeding disorders, use caution and consult your doctor. Also, avoid combining it with other pain relievers, blood thinners, blood pressure medications, or water pills. Always follow your doctor's advice, especially if you have underlying medical conditions or take other medications.
You can use Endonac Sp Tablet with the B complex because it does not interact with it. However, make sure to consult your doctor before taking it.
Yes, prolonged usage of the Endonac Sp Tablet may lead to kidney damage, especially for people who are already experiencing kidney problems. It is more important to take the Endonac Sp Tablet under medical supervision only. Your doctor may monitor your daily kidney function if you are prescribed to take the Endonac Sp Tablet for a long period based on your medical condition.
No, you shouldn'tshouldn't take more Endonac Sp Tablet than your doctor has prescribed. It causes major negative effects, including liver damage, renal damage, gastrointestinal bleeding, and cardiovascular problems, which might worsen with higher dosages. If you believe the recommended dosage is not having a significant impact on you, speak with your doctor right away to better understand your condition and receive better care.
Storage: Store the Endonac Sp Tablet in its original container to protect it from the external environment. Keep the medication out of reach of children. Store in a cool and dry place away from sunlight.Disposal: Do not consume it after the expiration date. Check the expiration date, remove the label, keep it in a plastic bag, and throw it in household trash. Do not flush the medication down the toilet or sink.
Some common side effects may include diarrhoea, indigestion, loss of appetite, nausea, stomach pain, stomach upset, and indigestion. Most of these side effects of Endonac Sp Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Endonac Sp Tablet should not be given to children without the prescription of a child specialist. Your doctor will determine the dose of the medicine depending on your child's weight and the severity of the condition.
There is insufficient information on Endonac Sp Tablet 's safety for nursing moms, so only take it as directed by a physician.

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