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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Endocryl Injection is indicated for the prevention of bleeding, wound closure, sclerotherapy, and mesh fixation. It contains N-butyl-cyanoacrylate which forms a strong bond between the wound edges. Thus, it arrests bleeding and promotes skin closure and healing. Avoid contact with fingers, gloves or surgical instruments. It should not be used in contaminated wounds as it might aggravate the infection.
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Prescription drug

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Prescription drug
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Synonym

ENBUCRILATE

Manufacturer/Marketer

Samarth Life Sciences Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Endocryl Injection

Endocryl Injection is a tissue adhesive solution indicated for the prevention of bleeding, wound closure, sclerotherapy, and mesh fixation. Endocryl Injection is used as an adhesive for lacerations (cut/tear) of the skin, used to treat arteriovenous malformations (abnormal connections between veins and arteries), and bleeding gastric varices.
 
Endocryl Injection contains N-butyl-cyanoacrylate, which polymerises quickly in connection with the tissue fluids and hardens immediately, leading to the formation of a strong bond between the wound edges. Thus, help stop bleeding and promotes skin closure and healing.
 
Endocryl Injection is a chemically active, free-flowing liquid which helps in wound bonding. The procedure of tissue glueing is simple, quick, and effective for the closure of wounds without any complications in comparison to conventional suturing.
 
Avoid contact of Endocryl Injection with fingers, gloves or surgical instruments. Endocryl Injection should not be used in contaminated wounds as it might aggravate the infection. The thick application of Endocryl Injection should be avoided as it does not enhance the bonding and may also tend to loosen and crack prematurely.

Uses of Endocryl Injection

Treatment of Tissue/wound closure, prevention of bleeding.

Medicinal Benefits

Endocryl Injection is used as an adhesive for lacerations (cut/tear) of the skin, used to treat arteriovenous malformations (abnormal connections between veins and arteries), and bleeding gastric varices. Endocryl Injection is a chemically active, free-flowing liquid which helps in wound bonding. The procedure of tissue glueing is simple, quick, and effective for the closure of wounds without any complications in comparison to conventional suturing. Endocryl Injection polymerises quickly in connection with the tissue fluids and hardens immediately, forming a strong bond between the wound edges. Thus, help stop bleeding and promotes skin closure and healing.

Directions for Use

A healthcare professional will apply Endocryl Injection ; do not use it on your own.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Avoid contact of Endocryl Injection with skin and eyes. Endocryl Injection should not be used in contaminated wounds as it might aggravate the infection. The thick application of Endocryl Injection should be avoided as it does not enhance the bonding and may also tend to loosen and crack prematurely. Avoid contact of Endocryl Injection with fingers, gloves or surgical instruments.

Drug Interactions

Drug-Drug Interactions: No interaction found/established.

Drug-Food Interactions: No interaction found/established.

Drug-Disease Interactions: No interaction found/established.

Habit Forming

No

Diet & Lifestyle Advise

  • Include foods that promote wound healing in your diet, such as meat, tofu, eggs, beans, milk, cheese, Greek yoghurt, soy, and fish.

  • Stay hydrated, as it is vital for promoting cell growth. Drink plenty of fluids.

  • Consume foods rich in vitamins A and C.

Disease/Condition Glossary

Laceration: A laceration is a wound that is caused by the tearing of soft body tissues. This kind of wound is generally irregular and jagged. Accidents with tools, knives, or machinery could lead to lacerations. A laceration may be caused by injury to a sharp object or due to impact injury from a blunt object. A laceration cut might be shallow or deep, short or long, and narrow or wide.

Arteriovenous malformations: It is the abnormal connection between veins and arteries, usually in the spine and brain. The arteries in such a condition can rupture, leading to bleeding in the brain/spine.

Bleeding gastric varices: Gastric varices are the dilated submucosal veins in the stomach lining that can cause bleeding in the upper gastrointestinal tract. These are most commonly found in patients with portal hypertension (high blood pressure in the portal vein), which could be a complication of cirrhosis. 

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Alcohol

Consult your doctor

It is not known if alcohol affects Endocryl Injection . Please consult a doctor.

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Pregnancy

Consult your doctor

Limited information is available regarding the use of Endocryl Injection during pregnancy. Please consult your doctor if you are pregnant or if you have any concerns regarding this.

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Breast Feeding

Consult your doctor

Limited information is available regarding the use of Endocryl Injection in breastfeeding women. Please consult your doctor if you are breastfeeding or if you have any concerns regarding this.

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Driving

Consult your doctor

It is not known if Endocryl Injection affects driving. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Limited information is available. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Limited information is available. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Limited information is available regarding the use of Endocryl Injection in children. Please consult a doctor if you have any concerns regarding this.

Country of origin

INDIA

Manufacturer/Marketer address

314, 3rd Floor, Welldone Tech Park, Sector-48, Sohna Road, Gurgaon- 122001
Other Info - END0027

Author Details

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FAQs

Endocryl Injection polymerises quickly in connection with the tissue fluids and hardens immediately, forming a strong bond between the wound edges. Thus, help stop bleeding and promotes skin closure and healing.
The procedure of tissue glueing using Endocryl Injection is simple, quick, and effective for the closure of wounds without any complications in comparison to conventional suturing. The average time for wound closure is one minute. It is less painful than suture materials.
Endocryl Injection is used in the fixation of hernia meshes, particularly in inguinal hernia surgery for implanting a prosthetic mesh.
Endocryl Injection is used in the closure of skin wounds without tension, such as incisions from minimally invasive surgery and clean surgical incisions. Endocryl Injection is also used in trauma-induced lacerations.

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Keep Refrigerated. Do not freeze.

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