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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 10, 2024 | 7:17 PM IST
Edicef SB 1000 mg/500 mg Injection is used to treat bacterial infections. It contains Cefotaxime and Sulbactam which work by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as pain and swelling at the injection site, skin rash, diarrhoea, nausea and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Scott Edil Pharmacia Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Edicef SB 1000 mg/500 mg Injection

Edicef SB 1000 mg/500 mg Injection belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Edicef SB 1000 mg/500 mg Injection is a combination of two medicines: Cefotaxime and Sulbactam. Cefotaxime is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Sulbactam inhibits the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (cefotaxime).

Edicef SB 1000 mg/500 mg Injection will be administered by a healthcare professional; do not self-administer. The common side effects of Edicef SB 1000 mg/500 mg Injection are pain and swelling at the injection site, skin rash, diarrhoea, nausea and vomiting. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Edicef SB 1000 mg/500 mg Injection if you are allergic to penicillin, any cephalosporin antibiotic or its contents. Before taking Edicef SB 1000 mg/500 mg Injection, inform your doctor if you have kidney problems, are on a low-salt diet, have diabetes or using other antibiotics. Do not discontinue or abruptly stop using Edicef SB 1000 mg/500 mg Injection as it may lead to antibiotic resistance (bacteria become resistant to antibiotics). Edicef SB 1000 mg/500 mg Injection is probably safe when used in children, pregnant women, breastfeeding mothers and elderly people. Edicef SB 1000 mg/500 mg Injection may not interact with alcohol. Edicef SB 1000 mg/500 mg Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Edicef SB 1000 mg/500 mg Injection

Treatment of Bacterial infections

Medicinal Benefits

Edicef SB 1000 mg/500 mg Injection contains Cefotaxime and Sulbactam. Cefotaxime is a cephalosporin antibiotic, whereas Sulbactam is a beta-lactamase inhibitor. Edicef SB 1000 mg/500 mg Injection has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria. It makes the drug effective in multiple serious bacterial infections including infections of the bloodstream (septicemia), bones (osteomyelitis), the heart valves (endocarditis), the membranes protecting the brain (meningitis) and the lining of the abdomen (peritonitis) and to prevent and treat infections following surgeries.

Directions for Use

Edicef SB 1000 mg/500 mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Edicef SB 1000 mg/500 mg Injection

  • Pain at the injection site
  • Swelling at the injection site
  • Skin rash
  • Diarrhoea
  • Nausea
  • Vomiting
  • Colitis (inflammation of the intestine)

Drug Warnings

Edicef SB 1000 mg/500 mg Injection may cause false-positive results when a urine test is performed to determine glucose levels, so let your doctor know that you are taking this medicine before undergoing laboratory tests. Edicef SB 1000 mg/500 mg Injection may contain sodium, so this medicine should be used with caution in people who are on a low-sodium diet. In individuals who were prescribed Edicef SB 1000 mg/500 mg Injection for more than ten days, blood counts should be regularly monitored. Edicef SB 1000 mg/500 mg Injection may cause a skin reaction called Steven-Johnson syndrome. So, stop taking Edicef SB 1000 mg/500 mg Injection and inform your doctor immediately if you notice a rash, blistering of the skin or itching while using Edicef SB 1000 mg/500 mg Injection. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics.

Drug Interactions

Drug-Drug Interactions:  Edicef SB 1000 mg/500 mg Injection may interact with penicillin antibiotics (mezlocillin and azlocillin), aminoglycoside antibiotics (streptomycin, neomycin, and gentamicin), diuretic or water pill (furosemide), and medicine used to treat gout (probenecid).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Edicef SB 1000 mg/500 mg Injection should be used with caution in patients with kidney problems and diabetes.

Drug-Drug Interactions Checker List

  • MEZLOCILLIN
  • AZLOCILLIN
  • STREPTOMYCIN
  • NEOMYCIN
  • GENTAMICIN
  • FUROSEMIDE
  • PROBENECID

Habit Forming

No

Diet & Lifestyle Advise

  • Probiotics should be taken after taking the full course of Edicef SB 1000 mg/500 mg Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.
  • Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid alcoholic beverages with Edicef SB 1000 mg/500 mg Injection as they can make you dehydrated and may affect your sleep.  This can make it harder for your body to aid the Edicef SB 1000 mg/500 mg Injection in fighting off infections.

Special Advise

  • If you are taking aminoglycoside antibiotics such as streptomycin and gentamicin, your kidney function should be regularly monitored.
  • Inform your doctor if you are allergic to penicillin or other antibiotics.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any organ of the body and multiply very quickly. Many give off chemicals called toxins, which can damage tissue and make you sick. Bacterial infections vary from minor illnesses (like sore throat and ear infections) to severe brain infections (like meningitis and encephalitis). When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills and fatigue. A few harmful bacteria that commonly cause infections include Streptococcus, Staphylococcus and E. coli. Anyone can get a bacterial infection but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.

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Alcohol

Safe if prescribed

Edicef SB 1000 mg/500 mg Injection may not interact with alcohol.

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Pregnancy

Safe if prescribed

Edicef SB 1000 mg/500 mg Injection is a category B medicine and may not cause harmful effects to the unborn baby. So, it is probably safe when used in pregnant women, when prescribed by a doctor.

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Breast Feeding

Safe if prescribed

Edicef SB 1000 mg/500 mg Injection is probably safe when used in breastfeeding mothers, when prescribed by a doctor.

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Driving

Caution

Edicef SB 1000 mg/500 mg Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Edicef SB 1000 mg/500 mg Injection should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Edicef SB 1000 mg/500 mg Injection should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Edicef SB 1000 mg/500 mg Injection is probably safe when used in children. However, the doctor may have to adjust the dose based on age, body weight and health condition.

Country of origin

India

Manufacturer/Marketer address

301,302,303 , Aditraj Arcade,Near Hetvi Tower, 100 Feet Ring Road, Satellite, Ahmedabad, Gujarat - 380015.
Other Info - ED53096

FAQs

Edicef SB 1000 mg/500 mg Injection is used to treat bacterial infections.
Edicef SB 1000 mg/500 mg Injection contains Cefotaxime and Sulbactam. Cefotaxime reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell wall (outer layer), which is essential for bacteria's survival. Sulbactam inhibits the action of beta-lactamase, an enzyme produced by the bacteria to destroy antibiotics (cefotaxime).
People allergic to penicillin should not take Edicef SB 1000 mg/500 mg Injection as they may develop cross-sensitivity (sensitivity to drugs with similar structures). Edicef SB 1000 mg/500 mg Injection contains cefotaxime, which has a similar structure to that of penicillin.
The common side-effects of Edicef SB 1000 mg/500 mg Injection are pain and swelling at the injection site, skin rash, diarrhoea, nausea, and vomiting. These side-effects usually don't require medical attention. However, inform your doctor immediately if any of these side-effects persist or get worse.
In individuals who have kidney problems, have diabetes and are on a low-salt diet, Edicef SB 1000 mg/500 mg Injection should be used with caution as this medicine may worsen the condition.
It is advised to let your doctor know that you are taking Edicef SB 1000 mg/500 mg Injection before undergoing any laboratory tests or having a blood transfusion. Edicef SB 1000 mg/500 mg Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Edicef SB 1000 mg/500 mg Injection may cause diarrhoea in some cases. Consult the doctor if you experience diarrhoea during treatment with Edicef SB 1000 mg/500 mg Injection.
Edicef SB 1000 mg/500 mg Injection starts working almost immediately after administering. However, it might take a few days to notice its full effects. To treat your condition effectively complete the duration of treatment.
Consult the doctor if you do not get better or if your condition persists even after completing the duration of treatment with Edicef SB 1000 mg/500 mg Injection.
The common side effects of Edicef SB 1000 mg/500 mg Injection are pain and swelling at the injection site, skin rash, diarrhoea, nausea and vomiting. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, inform your doctor immediately.

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