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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:18 PM IST
E Brium 25mg Tablet is used to treat nausea and vomiting due to Travel sickness (motion sickness). It is also used to treat the body's balancing problem that can be caused by Meniere disease, ringing in the ears, vertigo (a spinning sensation or dizziness), and hearing loss. It contains Cinnarizine, which helps in treating nausea and vomiting due to motion sickness. Also, it improves the blood flow in the inner ear. In some cases, it may cause side effects such as sleepiness, sweating, dry mouth, headache, weight gain, skin problems, and lethargy. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

CINNARIZINE-25MG

Manufacturer/Marketer

Med Manor Organics Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About E Brium 25mg Tablet

E Brium 25mg Tablet contains an 'antihistamine' medication, primarily used to treat nausea and vomiting due to Travel sickness (motion sickness). It is also used to treat the body's balancing problem that can be caused by Meniere disease, ringing in the ears, vertigo (a spinning sensation or dizziness), and hearing loss. Motion sickness is caused when nerves within your ear transmit faulty information about your brain's movement with signals.

E Brium 25mg Tablet contains Cinnarizine, which helps in treating nausea and vomiting due to motion sickness. It is known as a drowsy anti-histamine, which works by not allowing the constriction of the inner ear's blood vessels. As a result, this improves the circulation of the ear.

Take E Brium 25mg Tablet as prescribed by your doctor. You are advised to take E Brium 25mg Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take it after a meal to avoid an upset stomach. In some cases, you may experience sleepiness, sweating, dry mouth, headache, weight gain, skin problems, and lethargy. Most of these side effects of E Brium 25mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

E Brium 25mg Tablets should not be taken if you have a peptic ulcer, asthma, or low blood pressure. In patients with Parkinsonian disease, do not take E Brium 25mg Tablet as it can worsen your condition. If you are pregnant or planning to get pregnant, or are breastfeeding, it is recommended not to take E Brium 25mg Tablet. If your skin becomes yellow and urine also becomes pale yellow, consult your doctor immediately. Alcohol should not be consumed along with E Brium 25mg Tablet as it may cause excessive drowsiness.

Uses of E Brium 25mg Tablet

Treatment of Travel sickness (motion sickness), Vertigo (a spinning sensation or dizziness), Meniere's Disease.

Medicinal Benefits

E Brium 25mg Tablet contains an 'antihistamine' medication, Cinnarizine, primarily used to treat nausea and vomiting due to Travel sickness (motion sickness). It is also used to treat the body's balancing problem that can cause Vertigo, Meniere disease, ringing in the ears, vertigo (a spinning sensation or dizziness), and hearing loss. Motion sickness is caused when nerves within your ear transmit faulty information about your brain's movement with signals. It is known as a drowsy anti-histamine, which works by not allowing the constriction of the inner ear's blood vessels. As a result, this improves the circulation of the ear.

Directions for Use

Take E Brium 25mg Tablet with or without food as directed by your physician. Swallow it as a whole with a glass of water. Do not crush, chew, or break it. Preferably take it after a meal to avoid an upset stomach.

Storage

Store in a cool and dry place away from sunlight

Side Effects of E Brium 25mg Tablet

  • Sleepiness

  • Sweating

  • Dry mouth

  • Headache

  • Weight gain

  • Skin problems

  • Lethargy

Drug Warnings

Do not take E Brium 25mg Tablet if you are allergic to E Brium 25mg Tablet or any of its ingredients. Inform your doctor about all other medications, and herbal products you are taking or have been taking. If you have epilepsy or any other mental disorder, problem emptying the urinary bladder, porphyria (a blood disorder), glaucoma (increase eye pressure), or Parkinson's disease, inform your doctor before starting E Brium 25mg Tablet. Alcohol should not be consumed along with E Brium 25mg Tablet as it may cause excessive drowsiness. If you are pregnant or planning to get pregnant, or are breastfeeding, it is recommended not to take E Brium 25mg Tablet. If your skin becomes yellow and urine also becomes pale yellow, consult your doctor immediately.

Drug Interactions

Drug-Drug Interaction: E Brium 25mg Tablet is known to interact with antidepressants (amitriptyline, dosulepin, imipramine), and painkillers (ibuprofen, naproxen).

Drug-Food Interaction: Avoid the intake of alcohol with E Brium 25mg Tablet as it may cause increased drowsiness, dizziness, and lack of concentration.

Drug-Disease Interaction: E Brium 25mg Tablet may interact if you have or ever had epilepsy or any other mental disorder, problem emptying the urinary bladder, glaucoma (increased eye pressure), Parkinson's disease, kidney problem, or porphyria (a blood disorder).

Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DOSULEPIN
  • IMIPRAMINE
  • IBUPROFEN
  • NAPROXEN

Habit Forming

No

Diet & Lifestyle Advise

  • Try not to eat food immediately before traveling, as it will reduce your chances of vomiting while traveling.

  • Please do not drink alcohol as it could lead to excessive drowsiness.

  • Allow sufficient air to reach you while traveling as it will help reduce nausea, vomiting and reduce the ringing sensation of the ear.

Special Advise

  • Do not take E Brium 25mg Tablet if you are about to undergo a skin test for an allergic reaction.

Disease/Condition Glossary

Motion sickness: It is caused when nerves within your ear transmit faulty information about your brain's movement with signals. These nerves, along with signals from your eyes and muscles, enable your body to maintain a good sense of balance. It clashes with the signals received from your other ear, your eyes, or your body, whether the nerves in one of your ears transmit too many, too few or incorrect messages to your brain. Your brain is then confused, which can cause dizziness and a feeling of spinning (vertigo) and make you feel sick. Travel sickness is triggered while flying by frequent irregular movements. These repetitive motions, like going over bumps or around in a circle, give your brain loads of messages. The equilibrium system in your ear sends distinct signals to those in your eyes, which results in mixed and contradictory messages being received by your brain. This is what makes you feel ill. 

Meniere's Disease: It is a disorder of the inner ear that makes you feel dizzy and unwell. It can cause a spinning sensation, vertigo, and sometimes a hearing problem.

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Alcohol

Unsafe

E Brium 25mg Tablet should not be taken along with alcohol as it may increase sleepiness and drowsiness.

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Pregnancy

Caution

E Brium 25mg Tablet is a pregnancy category C drug. It is not known whether it will harm the baby or not. But, it is recommended not to take it during pregnancy.

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Breast Feeding

Unsafe

E Brium 25mg Tablet is not recommended in breastfeeding women.

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Driving

Caution

E Brium 25mg Tablet is known to cause sleepiness, so you should not operate any machinery or car which requires mental alertness.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using E Brium 25mg Tablet.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using E Brium 25mg Tablet.

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Children

Caution

E Brium 25mg Tablet is not recommended for children below the age of 5 years. For children aged 5 and above, the dose will be decided by a child specialist.

Country of origin

India

Manufacturer/Marketer address

16-11-477/45, Dilsukh Nagar, Hyderabad-500036, Telangana, India.
Other Info - EBRI341

Author Details

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FAQs

E Brium 25mg Tablet is used to treat nausea and vomiting due to Travel sickness (motion sickness). It is also used to treat the body's balancing problem that can be caused by Meniere disease, ringing in the ears, vertigo (a spinning sensation or dizziness), and hearing loss.
E Brium 25mg Tablet contains Cinnarizine, a drowsy anti-histamine, which works by not allowing the constriction of the inner ear's blood vessels. As a result, this improves the circulation of the ear.
Yes, E Brium 25mg Tablet can cause an upset stomach. It is best to take E Brium 25mg Tablet after a meal to avoid upsetting the stomach and also take it 1-2 hours before you are supposed to travel.
Taking E Brium 25mg Tablet if you have Parkinson's disease can aggravate the disease condition and worsen your condition. Although, when you stop taking E Brium 25mg Tablet, your condition might become normal. So, therefore it should be used with caution in patients with Parkinson's disease.
No, using E Brium 25mg Tablet for a long duration can increase the side effects of E Brium 25mg Tablet. It is mostly used for the long term in elderly patients with vertigo. So, E Brium 25mg Tablet should always be taken in dose and duration prescribed by your doctor.
Yes, E Brium 25mg Tablet can cause sleepiness as a common side effect, especially when you start taking it. It is advisable to avoid driving or operating heavy machinery until you know how the medication affects you. However, if you have any concerns consult your doctor.
Yes, E Brium 25mg Tablet can help with tinnitus. Tinnitus is a condition where you hear a ringing or buzzing sound that isn't caused by an external source. E Brium 25mg Tablet helps by improving blood flow to the inner ear, which can reduce the pressure of excess fluid and reduce symptoms like tinnitus. However if you experience it for long time, please consult your doctor.
Take E Brium 25mg Tablet before travelling as prescribed by your doctor.
Patients with Parkinson's disease may experience decreased motor function when taking E Brium 25mg Tablet. E Brium 25mg Tablet should be avoided in these patients. Although, this effect is reversible but may last for several days. Also, it can cause parkinsonian syndrome in older persons. Thus, it should be used with caution if advised by a doctor.
An overdose is likely to cause vomiting, drowsiness, coma, (unconsciousness) tremor (shaking) or hypotonia (floppy, relaxed state of muscles). If you suspect an overdose, consult your doctor immediately.
E Brium 25mg Tablet is generally not recommended for long-term use due to the increased the risk of uncontrollable movements and tremors. It is best to use it as prescribed by your doctor.
Take the E Brium 25mg Tablet exactly as prescribed by your doctor. It is best to take it after meals to minimize stomach upset. Swallow it with water. Do not break, crush or chew it.
It may cause weight gain as a side effect. To prevent this, you can eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. However, consult your doctor if you have any concerns.
The common side effects of E Brium 25mg Tablet are sleepiness, sweating, dry mouth, headache, weight gain, skin problems and lethargy. If these side effects persist or worsen, please consult your doctor.

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