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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Nov 23, 2024 | 4:28 PM IST
Dyskinil Tablet belongs to a group of medicines called anti-spasmodic drugs used in the treatment of Parkinson's disease and extrapyramidal symptoms (drug-induced movement disorders). This medicine contains trihexyphenidyl which works by relaxing the muscles and nerve impulses that control muscle functioning. Common side effects include nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, and drowsiness.
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Manufacturer/Marketer

Crescent Formulations Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Dyskinil Tablet

Dyskinil Tablet belongs to a group of medicines called anti-spasmodic agents used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements. 

Dyskinil Tablet contains ‘Trihexyphenidyl hydrochloride’, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, Dyskinil Tablet also balances chemical messengers called neurotransmitter in the brain, thereby improves muscle control and reduces stiffness, thus helps the muscles move naturally. 

You are advised to take Dyskinil Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience certain common side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not discontinue Dyskinil Tablet on your own. Consult your doctor before taking Dyskinil Tablet if you are pregnant or breastfeeding. Dyskinil Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Dyskinil Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Dyskinil Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your medicines and health condition to rule out any side effects.

Uses of Dyskinil Tablet

Treatment of Parkinson's disease

Medicinal Benefits

Dyskinil Tablet  contains Trihexyphenidyl hydrochloride, an anti-spasmodic agent used to treat the symptoms of Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Dyskinil Tablet exerts a direct inhibitory effect upon the parasympathetic nervous system. It works by relaxing the muscles and nerve impulses that control muscle functioning. Dyskinil Tablet improves muscle control and reduces stiffness, thereby helps the muscles move naturally. Dyskinil Tablet is used as an adjuvant therapy along with levodopa to treat Parkinson's disease. Additionally, Dyskinil Tablet is used to control drug-induced movement disorders caused by CNS drugs such as dibenzoxazepines, thioxanthenes, phenothiazines, and butyrophenones.

Directions for Use

Take Dyskinil Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water; do not chew, or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dyskinil Tablet

  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Weakness 
  • Headache
  • Dry mouth
  • Decreased urination
  • Drowsiness
  • Feeling nervous or restless

Drug Warnings

Do not take Dyskinil Tablet if you are allergic to any of its contents or if you have narrow angled glaucoma. Do not discontinue Dyskinil Tablet on your own. Inform your doctor before taking Dyskinil Tablet if you have glaucoma, prostate problems, urination problems, stomach ulcers, acidity, myasthenia gravis (muscle problems), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, heart, liver, or kidney problems. Do not take Dyskinil Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Dyskinil Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Dyskinil Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Dyskinil Tablet as it could lead to increased drowsiness and dizziness. 

Drug Interactions

Drug-Drug interactions: Dyskinil Tablet may have interaction with antipsychotic (aripiprazole, lurasidone, olanzapine, risperidone, quetiapine, trifluoperazine), MAO inhibitor (rasagiline), antihistamine (diphenhydramine), anti-cholinergic (benztropine), anti-convulsant (clonazepam, lamotrigine, pregabalin), anti-depressants (escitalopram, duloxetine) anti-anxiety (alprazolam), and mild pain killers/fever-reducing agent (acetaminophen).

Drug-Food interactions: Avoid consuming alcohol along with Dyskinil Tablet as it might increase dizziness, and drowsiness.

Drug-Disease interactions: Dyskinil Tablet may have interactions with disease conditions such as arrhythmia (irregular heartbeats), autonomic neuropathy (nerve damage), gastrointestinal obstruction, glaucoma, urinary obstruction, infectious diarrhoea, tardive dyskinesia (involuntary facial movements), psychoses, high blood pressure, and fever.

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • LURASIDONE
  • OLANZAPINE
  • RISPERIDONE
  • QUETIAPINE
  • TRIFLUOPERAZINE
  • RASAGILINE
  • DIPHENHYDRAMINE
  • BENZTROPINE MESYLATE
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • ESCITALOPRAM
  • DULOXETINE
  • ALPRAZOLAM
  • ACETAMINOPHEN

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

  • Take Dyskinil Tablet at least 2 hours after taking ketoconazole and antidiarrheal medicines as it may prevent the full absorption of trihexyphenidyl. Besides this, Dyskinil Tablet may prevent the complete absorption of antifungal agents like ketoconazole when these medicines are taken together.
  • Talk to your doctor immediately if you experience hallucinations.
  • Take special care with your dental hygiene while using Dyskinil Tablet (like brushing, flossing) and have regular dental check-ups.

Disease/Condition Glossary

Parkinson’s disease: It is a progressive neurological disorder in which the first signs are problems with movements. Dopamine is a naturally-occurring neurotransmitter in the brain which is reduced or absent in people with Parkinson’s disease. Due to this, problems arise with smooth and coordinated movements. Symptoms include decreased ability to smell, stooped posture, changes in voice, constipation, small/ cramped handwriting, tremor, slow movements, stiffness of arms, legs, trunk, and balance problems. 

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Dyskinil Tablet as it may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Dyskinil Tablet belongs to pregnancy category C. Please consult your doctor before taking Dyskinil Tablet if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Dyskinil Tablet passes into breastmilk. Consult your doctor before taking Dyskinil Tablet if you are breastfeeding.

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Driving

Unsafe

Dyskinil Tablet may cause dizziness, drowsiness and blurred vision. Avoid driving and handling machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Dyskinil Tablet is not recommended for use in children, as the safety and effectiveness have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

SCO-58, 59, Sector-17D Chandigarh-160017
Other Info - DYS0002

Author Details

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FAQs

Dyskinil Tablet belongs to a group of medicines called anti-spasmodic agents used as an adjunct to treat Parkinsons disease and extrapyramidal symptoms (drug-induced movement disorders).
Dyskinil Tablet works by relaxing the muscles and nerve impulses that control muscle functioning. It improves muscle control and reduces stiffness, thereby helps the muscles move naturally.
Dry mouth could be a side-effect of Dyskinil Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Dyskinil Tablet should be used with caution during hot weather as it may increase the chance of having a heat stroke. Dyskinil Tablet can cause decreased sweating which results in a rise in body temperature (hyperthermia). This profound side effect is more significant in hot weather, so it is advisable to drink plenty of fluids, especially in summer. Inform your doctor if you have heat intolerance or fever.
Antidepressants should be avoided while taking Dyskinil Tablet as it might increase sedative effects. Consult your doctor before taking Dyskinil Tablet if you are using anti-depressants.
Dyskinil Tablet may cause hallucination in some cases if taken for a prolonged time. Hallucination is a medical condition in which the person may feel, hear or believe things that are not true, see things that are not there, or feel unusually suspicious or confused. If you experience hallucinations while taking Dyskinil Tablet , please talk to your doctor immediately.
Constipation may occur as a side-effect of Dyskinil Tablet . Try eating foods that encourage a bowel movement. Consult your doctor if you experience excessive constipation.
Consult your doctor before taking Dyskinil Tablet if you have glaucoma. Dyskinil Tablet is contraindicated in patients with narrow-angle glaucoma. Dyskinil Tablet may cause blindness on long-term use in case of patients with narrow-angle glaucoma.
The dose of Dyskinil Tablet may vary from person to person. It will be determined by the doctor based on your medical condition. Please consult the doctor if you have any concerns.
No, you should not stop taking Dyskinil Tablet on your own as it may cause withdrawal symptoms like hallucinations, delusions, aggression or violent behaviour, and suicidal tendencies. Consult the doctor before stopping Dyskinil Tablet to prevent withdrawal symptoms.
Before taking Dyskinil Tablet , let your doctor know if you have glaucoma, heart, liver or kidney disease, prostate problems, trouble passing urine, myasthenia gravis (weakness of skeletal muscles), stomach ulcer, severe heartburn, acid indigestion or any other digestive disorders, or tardive dyskinesia (unusual movements of the face and tongue). Let the doctor know if you are taking an MAO inhibitor (rasagiline), anti-histamine (diphenhydramine), anti-anxiety (alprazolam), antipsychotic (aripiprazole, lurasidone, olanzapine, risperidone, quetiapine, trifluoperazine), anti-cholinergic (benztropine), anti-convulsant (clonazepam, lamotrigine, pregabalin), anti-depressants (escitalopram, duloxetine) and mild pain killers/fever-reducing agent (acetaminophen), levodopa, nefopam, parasympathomimetics (neostigmine, bethanechol), metoclopramide or domperidone.
Dyskinil Tablet can be taken orally with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not chew, or crush it.
No, Dyskinil Tablet is not a narcotic. It belongs to a group of medications called anticholinergic medication used to treat symptoms of Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders).
You will not get high after taking Dyskinil Tablet as it is not a narcotic. However, its hallucinogenic and euphoriant properties may lead some individuals to abuse. Therefore, Dyskinil Tablet should be taken only as advised by the doctor.
Yes, Dyskinil Tablet may cause drowsiness as a common side effect. If you experience drowsiness, avoid driving and operating machinery.
Do not take more than the recommended doses of Dyskinil Tablet as it may cause overdose symptoms like fever, drowsiness, agitation, dilated pupils, hallucinations, feeling hot, paleness in your face, dry skin and mouth, paranoia, seizure, or numbness in or around your mouth, nose, or throat. Always take Dyskinil Tablet in the dose prescribed by the doctor.
No, Dyskinil Tablet should not be crushed. It should be swallowed as a whole with a glass of water.
Dyskinil Tablet should be taken for as long as it has been prescribed by the doctor. The dose and duration will be determined by the doctor based on your medical condition.
Dyskinil Tablet is not known to cause weight gain. However, if you notice any weight changes, manage it with lifestyle changes by regular exercise, taking a balanced diet, cutting down sugary and processed foods and staying hydrated.
The side effects of Dyskinil Tablet include dizziness, drowsiness, nausea, vomiting, constipation, weakness, headache, dry mouth, decreased urination, and feeling nervous or restless. Consult the doctor if any of these symptoms persist or worsen.

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