Duphalac Enema Solution belongs to the group of medicines called laxatives used to treat constipation. Duphalac Enema Solution is also used to treat hepatic encephalopathy. Constipation refers to infrequent bowel movements in which the stools are often dry, painful and hard to pass. Hepatic encephalopathy is a liver disease which causes the accumulation of toxic substances in the bloodstream which are normally removed by the liver.

Duphalac Enema Solution contains 'lactulose' which works by absorbing water from the body and into the bowel. This softens stools and makes it easier to pass. Besides this, it also reduces the amount of ammonia in the blood of patients with liver disease by drawing ammonia from the blood into the colon, thereby facilitating the removal of toxins from the body.

You are advised to use Duphalac Enema Solution for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as diarrhoea, flatulence (wind), abdominal pain, nausea, and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Drink plenty of fluids (at least 6-8 glasses) while using Duphalac Enema Solution . Consult your doctor before using Duphalac Enema Solution if you are pregnant or breastfeeding. Duphalac Enema Solution should be given to children only if prescribed by a child specialist. Do not take Duphalac Enema Solution if you have galactosaemia (galactose indigestion disorder). Inform your doctor if you have diabetes, or if you are due to undergo a colonoscopy. Chronic use of unadjusted doses or misuse of Duphalac Enema Solution may cause diarrhoea and electrolyte imbalance, therefore take it only as advised by the doctor.

Duphalac Enema Solution belongs to a group of medicines known as laxatives used to treat constipation. It works by drawing water into the bowel and makes the stool softer and easier to pass, thereby providing relief from constipation. Duphalac Enema Solution is also used to treat hepatic encephalopathy. It works by reducing the amount of ammonia in the blood of patients with liver disease by drawing ammonia from the blood into the colon, thereby facilitating the removal of toxins from the body.

• Diarrhoea
• Flatulence (wind)
• Abdominal pain
• Nausea
• Vomiting

Do not take Duphalac Enema Solution if you are allergic to any of its contents; if you have galactosemia (galactose indigestion disorder), galactose or fructose intolerance, glucose-galactose malabsorption, Lapp lactase deficiency, intestinal blockage, or digestive perforation. Inform your doctor if you are unable to digest lactose/lactose intolerant, have diabetes, have irritable bowel syndrome, or if you are due to undergo a colonoscopy. Consult your doctor before using Duphalac Enema Solution if you are pregnant or breastfeeding. Chronic use of unadjusted doses or misuse of Duphalac Enema Solution may cause diarrhoea and electrolyte imbalance, therefore take it only as advised by the doctor.

Drug-Drug Interactions: Duphalac Enema Solution may have interaction with diuretic (furosemide), laxatives (docusate, polyethylene glycol), anti-emetic (ondansetron), and anti-psychotic (quetiapine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Duphalac Enema Solution may have interactions with conditions such as intestinal obstruction disorder, and galactosemia (galactose indigestion disorder).

• FUROSEMIDE
• DOCUSATE
• POLYETHYLENE GLYCOL
• ONDANSETRON
• QUETIAPINE

• Try maintaining a balanced diet that includes fresh fruits and vegetables.
• Stay hydrated, drink enough water and fluids.
• Exercise regularly, and stay fit.
• Get enough sleep.
• Try making time to empty your bowels whenever the body tells you to.
• Eat food rich in fiber such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs), and vegetables (broccoli, spinach, sweet potatoes, avocados).

If you are undergoing any surgery or tests on your rectum or colon, inform the doctor that you are using Duphalac Enema Solution .

Constipation: It refers to infrequent bowel movements. The stools are often dry, painful and hard to pass. Constipation is a medical condition in which the person has fewer than three bowel movements in a week. However, bowel patterns may vary from person to person. Symptoms include bloating, abdominal pain, and feeling as if the bowel movement is incomplete. Constipation occurs when the normal muscle contractions in the large intestine slow down, which causes the incomplete elimination of the bowel from the body. Constipation could be associated with a sudden change of diet, a diet with less fibre, not drinking enough liquids, and lack of exercise.

Hepatic encephalopathy: It is a liver/hepatic disease in which the liver does not remove the toxins from the body, which leads to loss of brain function. Hepatic encephalopathy causes confusion, tremor, decreased consciousness and coma.