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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
DUORANDIL 5MG TABLET is used to treat angina pectoris (heart-related chest pain). It contains Nicorandil which works by widening blood vessels and reducing the heart's workload by making it easier for the heart to pump blood around the body. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, dizziness, and weakness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

NICORANDIL-5MG

Manufacturer/Marketer

Sai Mirra Innopharma Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About DUORANDIL 5MG TABLET

DUORANDIL 5MG TABLET belongs to a class of medication called 'vasodilators' used to prevent or treat angina pectoris (heart-related chest pain) in adults who cannot take beta-blockers (blood pressure-lowering pills). Angina pectoris is a kind of chest pain due to decreased blood flow to the heart. It is a symptom of coronary artery disease.

DUORANDIL 5MG TABLET contains Nicorandil, a potassium-channel activator that opens potassium channels present on the muscle cells within the walls of blood vessels and relaxes these muscle cells and widens blood vessels. Thereby, DUORANDIL 5MG TABLET reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, DUORANDIL 5MG TABLET helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.

Take DUORANDIL 5MG TABLET as prescribed by your doctor. You are advised to take DUORANDIL 5MG TABLET for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience headache, nausea, vomiting, dizziness, weakness, flushing (reddening of the skin) or very fast, forceful or uneven heartbeat. Most of these side effects of DUORANDIL 5MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to DUORANDIL 5MG TABLET or any other medicines, please tell your doctor. Do not take DUORANDIL 5MG TABLET if you are pregnant or breastfeeding and consult a doctor. DUORANDIL 5MG TABLET is not recommended for children as the safety and effectiveness were not established. Drive only if you are alert as DUORANDIL 5MG TABLET may cause dizziness or weakness. Avoid alcohol consumption with DUORANDIL 5MG TABLET as it may cause severely low blood pressure. Avoid taking vardenafil, sildenafil, tadalafil and riociguat with DUORANDIL 5MG TABLET as it may affect blood pressure.

Uses of DUORANDIL 5MG TABLET

Treatment of Angina pectoris (heart related chest pain)

Medicinal Benefits

DUORANDIL 5MG TABLET contains Nicorandil, a potassium-channel activator used to prevent or treat angina pectoris (chest pain). DUORANDIL 5MG TABLET works by opening potassium channels present on the muscle cells within the blood vessels' walls and relaxes these muscle cells and widens blood vessels. Thereby, DUORANDIL 5MG TABLET reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, DUORANDIL 5MG TABLET helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart. DUORANDIL 5MG TABLET is given to adults who cannot tolerate other heart medicines such as calcium antagonists or beta-blockers. 

Directions for Use

Take DUORANDIL 5MG TABLET with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DUORANDIL 5MG TABLET

  • Headache
  • Nausea
  • Vomiting
  • Dizziness
  • Weakness
  • Flushing (reddening of the skin)
  • Uneven heartbeat

Drug Warnings

If you are allergic to DUORANDIL 5MG TABLET or any other medicines, please tell your doctor. Avoid taking DUORANDIL 5MG TABLET if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems. Do not take DUORANDIL 5MG TABLET if you are pregnant or breastfeeding and consult a doctor. DUORANDIL 5MG TABLET is not recommended for children as the safety and effectiveness were not established. Drive only if you are alert as DUORANDIL 5MG TABLET may cause dizziness or weakness. Avoid alcohol consumption with DUORANDIL 5MG TABLET as it may cause severely low blood pressure. Avoid taking vardenafil, sildenafil, tadalafil and riociguat with DUORANDIL 5MG TABLET as it may affect blood pressure. If you notice in blood in stools while taking DUORANDIL 5MG TABLET, inform your doctor immediately as it may be due to ulcers in the stomach, intestines or back passage.

Drug Interactions

Drug-Drug Interaction: DUORANDIL 5MG TABLET may interact with medicines used to treat erectile dysfunction (vardenafil, sildenafil, tadalafil), drugs to treat pulmonary hypertension (riociguat), medicine to treat premature ejaculation (dapoxetine), pain reliever (aspirin), steroids (prednisolone), high blood pressure-lowering medicines (lisinopril, ramipril, losartan, valsartan, candersartan).

Drug-Food Interaction: DUORANDIL 5MG TABLET may interact with alcohol. Therefore, avoid alcohol intake while taking DUORANDIL 5MG TABLET as it may cause severely low blood pressure.

Drug-Disease Interaction: Avoid taking DUORANDIL 5MG TABLET if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (build-up of fluid in the lungs) or any heart problems.

Drug-Drug Interactions Checker List

  • VARDENAFIL
  • SILDENAFIL
  • TADALAFIL
  • RIOCIGAUT
  • DAPOXETINE
  • ASPIRIN
  • PREDNISOLONE
  • LISINOPRIL
  • RAMIPRIL
  • LOSARTAN
  • VALSARTAN
  • CANDESARTAN

Habit Forming

No

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.

  • Consume low-salt and a low-fat diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans-fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Special Advise

  • Avoid consumption of alcohol with name as it may cause severe low blood pressure.

  • Regular exercise is recommended along with DUORANDIL 5MG TABLET for effective results.

Disease/Condition Glossary

Angina pectoris: It is a kind of chest pain caused due to decreased blood flow to the heart, which means insufficient oxygen supply to the heart muscle. The chest pain is often triggered by emotional stress or physical activity. Angina is a symptom of coronary artery disease. The symptoms of angina include dizziness, shortness of breath, nausea, tiredness, anxiety or excessive sweating. The risk factors for angina include smoking, diabetes, overweight, high blood pressure, high cholesterol, not exercising, or a history of heart disease. 

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with DUORANDIL 5MG TABLET as it may cause severely low blood pressure.

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Pregnancy

Unsafe

DUORANDIL 5MG TABLET is not recommended for pregnant women as it may harm the foetus. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

DUORANDIL 5MG TABLET is contraindicated in breastfeeding women. Please consult a doctor if you are breastfeeding.

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Driving

Caution

DUORANDIL 5MG TABLET may cause dizziness or weakness in some people. Therefore, avoid driving if you feel dizzy or weak after taking DUORANDIL 5MG TABLET.

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Liver

Caution

Take DUORANDIL 5MG TABLET with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take DUORANDIL 5MG TABLET with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

DUORANDIL 5MG TABLET is not recommended for children as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

No. 23, Pizza Corner Building, No. 4, 3rd Floor, Lattice Bridge Road, Adyar, Chennai-600020, Tamil Nadu, India
Other Info - DUO0035

Author Details

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FAQs

DUORANDIL 5MG TABLET is used to prevent or treat angina pectoris (heart-related chest pain) in adults who cannot take beta-blockers (blood pressure-lowering pills).
DUORANDIL 5MG TABLET contains Nicorandil that works by relaxing and widening blood vessels. Thereby, DUORANDIL 5MG TABLET reduces the workload of the heart by making it easier for heart to pump blood around the body and does not require much oxygen. Also, DUORANDIL 5MG TABLET helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.
DUORANDIL 5MG TABLET may cause headache as a common side effect especially in the first few days of treatment. However, if the condition persist or worsens, please consult a doctor so that the dose may be reduced initially.
DUORANDIL 5MG TABLET is not recommended for patients with severe hypotension (low blood pressure) as it may increase the risk of worsening the condition. Therefore, inform your doctor if you have low blood pressure before taking DUORANDIL 5MG TABLET.
You are not recommended to take aspirin (pain reliever) with DUORANDIL 5MG TABLET as co-administration of these two medicines may increase the risk of ulcers or other adverse effects. However, please consult a doctor before taking other medicines with DUORANDIL 5MG TABLET.
You are recommended to avoid taking DUORANDIL 5MG TABLET if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems such as left ventricular failure with low filling pressure, cardiac decompensation or cardiogenic shock.
You are not recommended to take more than the prescribed dose of DUORANDIL 5MG TABLET as it may cause DUORANDIL 5MG TABLET overdose resulting in symptoms such as weakness, dizziness (signs of low blood pressure), fast or irregular heartbeat. However, if you experience any of these symptoms while taking DUORANDIL 5MG TABLET, please consult a doctor immediately.

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