Drotamef 80 mg/250 mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Drotamef 80 mg/250 mg Tablet is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Drotamef 80 mg/250 mg Tablet helps in relieving pain.

You are advised to take Drotamef 80 mg/250 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have/had asthma, peptic ulcers, porphyria, or bleeding problems. Consult your doctor if you are pregnant or breastfeeding. Drotamef 80 mg/250 mg Tablet may cause dizziness, so drive with caution. Drotamef 80 mg/250 mg Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drotamef 80 mg/250 mg Tablet is a combination of two drugs: Drotaverine and Mefenamic acid. Drotamef 80 mg/250 mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Drotaverine is an antispasmodic that reduces calcium reuptake by the cells, thereby correcting the calcium levels in the body and relieving contractions associated with smooth muscles. Mefenamic acid is an NSAID which works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Drotamef 80 mg/250 mg Tablet helps in relieving pain.

• Gastrointestinal disturbances
• Feeling thirsty
• Nausea
• Vomiting
• Diarrhoea
• Dry mouth
• Rashes
• Itching

Do not take Drotamef 80 mg/250 mg Tablet if you are allergic to any of its contents. Inform your doctor if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. If you have had any recent heart surgery, do not take Drotamef 80 mg/250 mg Tablet unless prescribed by the doctor, as Drotamef 80 mg/250 mg Tablet may increase the risk of heart attack or stroke. Inform your doctor if you have/had asthma, peptic ulcers, porphyria, bleeding problems, liver or kidney impairment. Consult your doctor if you are pregnant or breastfeeding. Drotamef 80 mg/250 mg Tablet may cause dizziness, so drive only if you are alert. Drotamef 80 mg/250 mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol as it could lead to increased drowsiness and may increase the risk of stomach bleeding. Stop taking Drotamef 80 mg/250 mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Drotamef 80 mg/250 mg Tablet unless prescribed.

Drug-Drug Interactions: Drotamef 80 mg/250 mg Tablet may interact with pain killers (aspirin, ibuprofen, celecoxib), anticoagulants (warfarin), anti-Parkinson's (levodopa), immunosuppressants (cyclosporine, tacrolimus), anti-gout (probenecid), anti-depressant (duloxetine, lithium, fluoxetine, sertraline), cardiac glycosides (digoxin), anti-rheumatoid (methotrexate), anti-HIV (zidovudine), and antiprogestational steroids (mifepristone).

Drug-Food Interactions: Avoid alcohol consumption while taking Drotamef 80 mg/250 mg Tablet as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: Inform your doctor if you have peptic ulcers, bleeding disorders, low blood pressure, diabetes, Crohn's disease, inflammatory bowel disease, heart, kidney or liver problems.

• ASPIRIN
• IBUPROFEN
• CELECOXIB
• WARFARIN
• LEVODOPA
• CYCLOSPORINE
• TACROLIMUS
• PROBENECID
• DULOXETINE
• LITHIUM
• FLUOXETINE
• SERTRALINE
• DIGOXIN
• METHOTREXATE
• ZIDOVUDINE
• MIFEPRESTONE

• Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
• Massages can also be helpful.
• Avoid freezing and hot temperatures.
• Avoid wearing tight-fitting clothes; instead, wear loose garments.
• Rest well, and get plenty of sleep.
• To avoid developing pressure sores, change your position at least every two hours.
• Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot-pack on the muscle for 15-20minutes.
• Stay hydrated, drink plenty of water.

Pain: It is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis, and stomach aches. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.