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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:22 PM IST
Dpine H 5mg/12.5mg Tablet is used for the treatment of hypertension (high blood pressure). It contains Amlodipine and Hydrochlorothiazide, which work by relaxing and widening the blood vessels. Also, it helps to remove extra water and certain electrolytes from the body through urine. Thus, it lowers high blood pressure and reduces the chances of future heart attack and stroke. It may cause side effects such as glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache, (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, increased blood uric acid, and altered blood lipid level. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Dpine H 5mg/12.5mg Tablet

Dpine H 5mg/12.5mg Tablet belongs to the class of anti-hypertensives and is primarily taken for the treatment of hypertension (high blood pressure). Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications. Edema may occur in case of high blood pressure, where fluids of the body get trapped in the tissues of the hands, arms, feet, ankles, and legs, leading to swelling.

Dpine H 5mg/12.5mg Tablet is a combination of two medicines, including Amlodipine and Hydrochlorothiazide, which are antihypertensive medicines. Amlodipine is a calcium channel blocker and works by relaxing and widening the blood vessels. Hydrochlorothiazide is a diuretic, and its function is to remove extra water and certain electrolytes from the body through urine. Dpine H 5mg/12.5mg Tablet helps to lower high blood pressure, thus reducing the chances of future heart attack and stroke. Over time it also performs by relaxing vessels of blood and enhancing the flow of blood.

Take Dpine H 5mg/12.5mg Tablet as prescribed. You may experience glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache, (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, Increased blood uric acid, and altered blood lipid level. Most of these side effects of Dpine H 5mg/12.5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have had an allergic reaction to Dpine H 5mg/12.5mg Tablet, have liver disease, kidney disease, heart failure, a heart valve problem, or have a history of a heart attack. Immediately contact your doctor if you are pregnant or are planning to get pregnant, or are breastfeeding. Do not stop taking $ name without your doctor's advice. Sudden Stopping Dpine H 5mg/12.5mg Tablet may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period to help prevent these symptoms.

Uses of Dpine H 5mg/12.5mg Tablet

Treatment of Hypertension

Medicinal Benefits

When you take Dpine H 5mg/12.5mg Tablet, it works by relaxing the blood vessels and making the heart more efficient at pumping blood throughout the body. It helps to lower high blood pressure, thus reducing the chances of future heart attack and stroke. It removes the extra water and certain electrolytes from the body through urine.

Directions for Use

Take Dpine H 5mg/12.5mg Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dpine H 5mg/12.5mg Tablet

  • Glucose intolerance (low or high level of glucose)

  • Ankle swelling

  • Sleepiness

  • Headache

  • Flushing (sense of heat in the face, ears, neck, and trunk)

  • Tiredness

  • Nausea

  • Decreased potassium level in the blood

  • Increased blood uric acid

  • Altered blood lipid level

Drug Warnings

Dpine H 5mg/12.5mg Tablet should be used with extreme caution in patients with liver, kidney, cardiovascular diseases, and diabetic patients. Use only if the potential benefit justifies the potential risk. Immediately contact your doctor if you are pregnant or are planning to get pregnant, are breastfeeding. Do not stop taking $ name without your doctor's advice. Sudden Stopping Dpine H 5mg/12.5mg Tablet may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. please consult your doctor, your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Drug Interactions

Drug-drug interaction: Dpine H 5mg/12.5mg Tablet may have an interaction with medicines used to treat mood disorders such as (lithium), medicines used to treat heart disorders such as (digoxin), antidiabetic medicines such as (metformin), medicines used to treat erectile dysfunction such as (sildenafil), medicines used to lower cholesterol levels such as (simvastatin), ACE-inhibitor (such as enalapril, lisinopril, ramipril), and medicines used for immunosuppression such as (cyclosporine).

Drug-Food Interaction: Avoid foods with high fat or cholesterol. Avoid too much salt in your diet like pickles, extra salt on salad, etc. You are recommended not to consume alcohol along with Dpine H 5mg/12.5mg Tablet to avoid unpleasant side effects.

Drug-Disease Interaction: Dpine H 5mg/12.5mg Tablet should not be given to people with cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), liver disease, kidney disease, or heart failure, low serum potassium (hypokalemia), patients with nil urine output (anuria).

Drug-Drug Interactions Checker List

  • LITHIUM
  • DIGOXIN
  • METFORMIN
  • SILDENAFIL
  • SIMVASTATIN
  • ENALAPRIL
  • LISINOPRIL
  • RAMIPRIL
  • CYCLOSPORINE

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Avoid stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Option for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.

  • Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.

Special Advise

  • It is advised to restrict salt intake in the diet.

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Dpine H 5mg/12.5mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Dpine H 5mg/12.5mg Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Dpine H 5mg/12.5mg Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Unsafe

It is advised to drive with caution after taking Dpine H 5mg/12.5mg Tablet as it usually causes drowsiness and affects the driving ability.

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Liver

Caution

Dpine H 5mg/12.5mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Dpine H 5mg/12.5mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.

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Children

Caution

Dpine H 5mg/12.5mg Tablet to be taken with caution, especially if you are children below the age of 12. Your doctor may adjust your dose depending upon your age.

Country of origin

India

Manufacturer/Marketer address

Plot No. 398, Industrial Area, Phase-1, Panchkula 134113
Other Info - DP61653

Author Details

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FAQs

Dpine H 5mg/12.5mg Tablet is used for the treatment of hypertension (high blood pressure).
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
In case you forget to take the Dpine H 5mg/12.5mg Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.
Yes, Dpine H 5mg/12.5mg Tablet may cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Dpine H 5mg/12.5mg Tablet. In case you feel dizzy or light-headed, it is advised to rest for some time until you feel better.
Dpine H 5mg/12.5mg Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.
No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.
Take Dpine H 5mg/12.5mg Tablet once a day, at the same time each day, with or without food. Usually, take it in the morning to help control blood pressure throughout the day. Remember to follow your doctor's instructions and take it at the same time daily to make it a habit.
While taking Dpine H 5mg/12.5mg Tablet, consult your doctor before adding any supplements to control blood pressure. Supplements can interact with the medication or increase side effects. Always consult your doctor to make an informed decision and ensure safe usage. They will help you determine the best course of action.
If you feel nauseous after taking Dpine H 5mg/12.5mg Tablet, it's a common side effect that usually goes away with time. If it persists or bothers you, consult your doctor. In the meantime, take the tablet with food and stay hydrated to help manage nausea.
While taking Dpine H 5mg/12.5mg Tablet, monitoring your vital signs and health indicators is essential. This includes keeping track of your blood pressure to ensure the medication is effectively controlling your hypertension, as well as regular blood tests to check your kidney function, potassium levels, and blood sugar levels, especially if you have diabetes. Additionally, monitoring your electrolyte levels, including potassium, sodium, and chloride, will help detect any imbalances.
Try using a pill box to organize your medicines or set reminders on your phone or calendar. You can also take your medications at the same time each day or ask a family member or friend to remind you. Additionally, you can place sticky notes in visible spots or explore medication reminder apps to help you stay on track. Choose the method that works best for you.
The key active components present in Dpine H 5mg/12.5mg Tablet are Amlodipine and Hydrochlorothiazide, which are antihypertensive medicines. Amlodipine, a calcium channel blocker, relaxes blood vessels, improving blood flow and reducing blood pressure. Hydrochlorothiazide, a diuretic, helps remove excess fluid from the body, reducing blood volume and blood pressure. These two medicines work together synergistically to effectively manage hypertension (high blood pressure).
Common side effects of Dpine H 5mg/12.5mg Tablet may include glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, Increased blood uric acid, and altered blood lipid level. Most of these side effects of Dpine H 5mg/12.5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Avoid or limit alcohol consumption while taking Dpine H 5mg/12.5mg Tablet. Alcohol can increase the blood pressure-lowering effect of the medication, leading to dizziness or fainting. It can also increase the risk of dehydration and electrolyte imbalances. If you do drink alcohol, do so in moderation and consult your doctor for personalized advice.
Dpine H 5mg/12.5mg Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and potential risks before prescribing it.
Dpine H 5mg/12.5mg Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and potential risks before prescribing it. Please consult your doctor.

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