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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Nov 23, 2024 | 4:30 PM IST
Dofine Tablet is a combination medicine primarily used to treat the common cold. This medicine works by inhibiting the action of histamine, a chemical messenger responsible for causing allergies. It helps relieve congestion, sneezing, nasal and sinus congestion, and nasal swelling, common cold, flu, allergies and other breathing problems like sinusitis and bronchitis. Common side effects include drowsiness, headache, dizziness, tiredness, disturbance in attention, and dry mouth.
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Prescription drug

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Synonym

CAFFEINE+DIPHENHYDRAMINE HYDROCHLORIDE+PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE

Manufacturer/Marketer

Care Fine Drugs Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Dofine Tablet

Dofine Tablet is used to treat symptoms of the common cold, such as sneezing, runny nose, fever, headache, body pains, congestion, stuffy nose, or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as “rhinoviruses”. The virus enters the body through the nose, mouth, or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs, or talks.

Dofine Tablet is a combination of four drugs: Caffeine, Diphenhydramine, Paracetamol and Phenylephrine. Caffeine is a stimulant that increases the effect of paracetamol. Diphenhydramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreasing mucus production. Together, Dofine Tablet helps to provide relief from common cold symptoms.

Take Dofine Tablet as prescribed by your doctor. You are advised to take Dofine Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience drowsiness, headache, dizziness, tiredness, disturbance in attention, and dry mouth. Most of these side effects of Dofine Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Dofine Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, you are advised to consult a doctor before taking Dofine Tablet . Dofine Tablet is not recommended for children below 12 years. Please do not take more than the prescribed dose of Dofine Tablet as it may cause severe liver damage. Avoid excessive intake of caffeine as it may cause shaking, difficulty sleeping, and uncomfortable feelings in the chest.

Uses of Dofine Tablet

Treatment of Common cold symptoms

Medicinal Benefits

Dofine Tablet contains Caffeine, Diphenhydramine, Paracetamol and Phenylephrine. Caffeine is a stimulant that increases the effect of paracetamol and decreases drowsiness caused by Diphenhydramine. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Diphenhydramine is an anti-allergic drug that blocks the action of histamine, a substance responsible for causing allergic reactions.  Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreasing mucus production. Together, Dofine Tablet helps to provide relief from symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Directions for Use

Take Dofine Tablet with or without food as prescribed by your doctor. Swallow it whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dofine Tablet

  • Drowsiness

  • Headache

  • Dizziness

  • Tiredness

  • Disturbance in attention

  • Dry mouth

Drug Warnings

If you are allergic to Dofine Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, you are advised to consult a doctor before taking Dofine Tablet . Dofine Tablet is not recommended for children below 12 years. Do not take more than the prescribed dose of Dofine Tablet as it may cause severe liver damage. Avoid excessive intake of caffeine as it may cause shaking, difficulty sleeping and uncomfortable feeling in the chest. If you experience anxiety, nervousness, diarrhoea, high blood pressure or dizziness while taking Dofine Tablet , please consult a doctor.

Drug Interactions

Drug-Drug Interaction: Dofine Tablet may interact with a cholesterol-lowering agent (colestyramine), medicines used to control nausea (domperidone, metoclopramide), blood thinner (warfarin), beta-blockers (atenolol), antihypertensives (methyldopa) and ganglion blocking agent (trimetaphan camsylate).

Drug-Food Interaction: Avoid foods rich in carbohydrates, and pectin including jellies, cabbage, brussels sprouts, and broccoli as Dofine Tablet may interact with these foods. Also, avoid the intake of Dofine Tablet with chocolate and caffeine-containing foods such as tea, coffee, colas, and some herbal supplements,  as they may increase the risk of severity of side effects. Avoid consumption of alcohol with Dofine Tablet it may as it may increase the risk of liver damage and cause increased drowsiness, dizziness, and difficulty in concentrating.

Drug-Disease Interaction: If you have high blood pressure, myasthenia gravis (muscle weakness), seizures (fits),  glaucoma, hyperthyroidism (overactive thyroid), chronic obstructive pulmonary disease (COPD), enlarged prostate gland, kidney, liver, heart or urinary problems, inform your doctor before taking Dofine Tablet .

Drug-Drug Interactions Checker List

  • CHOLESTYRAMINE
  • DOMPERIDONE
  • METOCLOPRAMIDE
  • WARFARIN
  • ATENOLOL
  • METHYLDOPA
  • TRIMETAPHAN

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.

  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.

  • Drink plenty of fluids to avoid dehydration. 

  • Gargle with salt water for relief from sore throat. 

  • Avoid consumption of alcohol with Dofine Tablet as it may cause tiredness, drowsiness or lack of concentration.

Disease/Condition Glossary

Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’, affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected by having 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The symptoms of the common cold include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, and stuffy or runny nose.

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Alcohol

Unsafe

Avoid consumption of alcohol with Dofine Tablet as it may increase the risk of liver damage and cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with Dofine Tablet .

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Pregnancy

Unsafe

Dofine Tablet is not recommended for pregnant women. However, please consult a doctor if you are pregnant.

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Breast Feeding

Caution

Please consult a doctor before taking Dofine Tablet if you are a breastfeeding mother.

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Driving

Caution

Dofine Tablet may cause blurred vision, dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Dofine Tablet .

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Liver

Caution

Take Dofine Tablet with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Dofine Tablet with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Dofine Tablet is not recommended for children below 12 years of age. However, please consult a doctor before giving Dofine Tablet to children.

Country of origin

India
Other Info - DOF0028

Author Details

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FAQs

Dofine Tablet is used to treat symptoms of the common cold, such as sneezing, runny nose, fever, headache, body pains, congestion, stuffy nose, or watery eyes.
Dofine Tablet contains Caffeine, Diphenhydramine, Paracetamol and Phenylephrine. Caffeine increases the effect of paracetamol and decreases drowsiness caused by Diphenhydramine. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Diphenhydramine blocks the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreasing mucus production. Together, Dofine Tablet helps to provide relief from symptoms of the common cold.
Yes, Dofine Tablet may cause drowsiness. It is not necessary for everyone taking Dofine Tablet to experience this side effect. Therefore, avoid driving if you feel drowsy after taking Dofine Tablet .
Dofine Tablet may be used to relieve pain and fever. Dofine Tablet contains Paracetamol, an analgesic (relieves pain) and antipyretic (reduces fever) that inhibits the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
You are not recommended to take Dofine Tablet with medicines containing Paracetamol. However, please consult a doctor before taking Dofine Tablet with other medicines.
No, you are not recommended to stop taking Dofine Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Dofine Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Dofine Tablet , please consult your doctor.
While taking Dofine Tablet you should avoid foods rich in carbohydrates and pectin like jellies, cabbage, and broccoli, as well as chocolate, caffeine-containing foods. Also, avoid consumption of alcohol with Dofine Tablet as it may increase the risk of liver damage and causes increased drowsiness, dizziness, and difficulty in concentrating. However take the advice of your doctor if you have any concerns.
Dofine Tablet may rarely cause serious side effects which includes allergic reactions, skin rash or peeling, mouth ulcers, breathing problems, unexplained bleeding, recurrent fevers or infections, vision disturbances and fast or irregular heartbeat. If you experience any of these symptoms, please consult your doctor immediately.
No, it is not advisable to breastfeed while using Dofine Tablet , as it contains diphenhydramine, which can enter breast milk and can be harmful to the unborn child. Therefore, consult your doctor before starting Dofine Tablet if you are breastfeeding.
No, taking a higher than the recommended dose of Dofine Tablet will not make it more effective and can actually increase the risk of serious side effects and toxicity. If you feel that your current dose is not effective, consult your doctor.
If you allergic to Dofine Tablet , avoid taking it. If you have high blood pressure, myasthenia gravis (muscle weakness), seizures (fits), glaucoma, hyperthyroidism (overactive thyroid), chronic obstructive pulmonary disease (COPD), enlarged prostate gland, kidney, liver, heart and urinary problems, inform your doctor before taking Dofine Tablet .
Store Dofine Tablet at room temperature in a cool and dry place away from sunlight. Keep it out of reach of children.
The common side effects of Dofine Tablet are drowsiness, headache, dizziness, tiredness, disturbance in attention, and dry mouth. If any of these side effects persist or worsen, please consult your doctor.

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