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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Dixin 0.5 mg Injection 10 x 2 ml is an antiarrhythmic medicine used in the treatment of heart failure and irregular heartbeats. It mainly acts on heart muscles. This medication contains digoxin which strengthens the heart muscle's contractions with each heartbeat and thereby increases the heart's efficiency in pumping blood throughout the body. Common side effects include diarrhoea, nausea, dizziness, weakness, headache, etc.
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Composition

DIGOXIN-0.5MG

Manufacturer/Marketer

Samarth Life Sciences Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Dixin 0.5 mg Injection 10 x 2 ml

Dixin 0.5 mg Injection 10 x 2 ml is used to treat heart failure and irregular heartbeats. Heart failure is a chronic condition in which the heart is unable to pump blood as effectively as it should. Irregular heartbeat is a condition in which the heart beats irregularly, i.e., too fast, or too slow. 

Dixin 0.5 mg Injection 10 x 2 ml contains Digoxin, which works on the heart muscle and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

Dixin 0.5 mg Injection 10 x 2 ml will be administered by a healthcare professional; do not self-administer. Some people may experience diarrhoea, nausea, dizziness, weakness, headache, or anxiety. Most of these side effects of Dixin 0.5 mg Injection 10 x 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. 

If you are known to be allergic to Digoxin or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking Dixin 0.5 mg Injection 10 x 2 ml . If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (inability to absorb minerals from food), or any lung or kidney disease, please inform your doctor before taking Dixin 0.5 mg Injection 10 x 2 ml so that the dose may be adjusted or an alternate medicine may be prescribed accordingly.

Uses of Dixin 0.5 mg Injection 10 x 2 ml

Prevention of heart failure and Irregular heartbeats

Medicinal Benefits

Dixin 0.5 mg Injection 10 x 2 ml is a cardiac glycoside that is used to treat heart failure and irregular heartbeats. Dixin 0.5 mg Injection 10 x 2 ml increases the force with which the heart muscle contracts with each heartbeat and makes the heart efficient in pumping blood around the body. Thus, slows down the rate at which the heart beats and makes the heart rate normal. Dixin 0.5 mg Injection 10 x 2 ml improves heart failure symptoms such as exercise capacity and reduces the number of hospitalizations.

Directions for Use

Dixin 0.5 mg Injection 10 x 2 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dixin 0.5 mg Injection 10 x 2 ml

  • Diarrhoea
  • Nausea
  • Dizziness
  • Weakness
  • Headache
  • Anxiety

Drug Warnings

If you are known to be allergic to Dixin 0.5 mg Injection 10 x 2 ml or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking Dixin 0.5 mg Injection 10 x 2 ml . Avoid intake of alcohol with Dixin 0.5 mg Injection 10 x 2 ml as it may increase the risk of drowsiness. Dixin 0.5 mg Injection 10 x 2 ml may cause vision problems in some people; drive or operate machinery only if you are alert. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking Dixin 0.5 mg Injection 10 x 2 ml so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Dixin 0.5 mg Injection 10 x 2 ml has a narrow therapeutic index which makes its use limited and requires close monitoring as a small change in dose or blood concentration may lead to severe adverse effects and overdose may lead to life-threatening reactions.

Drug Interactions

Drug-Drug Interaction: Dixin 0.5 mg Injection 10 x 2 ml may have interaction with medicines used to treat irregular heartbeat (adenosine, amiodarone, dolasetron, quinidine), cardiac stimulants (arbutamine), HIV/AIDS drugs (atazanavir, saquinavir), anticancer drugs (ceritinib, lapatinib), antibiotics (clarithromycin), immunosuppressants (fingolimod), antidepressants (flibanserin), antifungal drugs (itraconazole) and calcium supplements (calcium chloride, calcium gluceptate, calcium gluconate). 

Drug-Food Interaction: Dixin 0.5 mg Injection 10 x 2 ml may interact with alcohol. Therefore, avoid alcohol intake while taking Dixin 0.5 mg Injection 10 x 2 ml .

Drug-Disease Interaction: If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking Dixin 0.5 mg Injection 10 x 2 ml .

Drug-Drug Interactions Checker List

  • ADENOSINE
  • AMIODARONE
  • DOLASETRON
  • QUINIDINE
  • ARBUTAMINE
  • ATAZANAVIR
  • SAQUINAVIR
  • CERITINIB
  • LAPATINIB
  • CLARITHROMYCIN
  • FINGOLIMOD
  • FLIBANSERIN
  • ITRACONAZOLE
  • CALCIUM CHLORIDE
  • CALCIUM GLUCEPTATE
  • CALCIUM GLUCONATE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.

  • Regular exercise is advised as it helps to lower blood pressure and keeps blood vessels and the heart in good condition.

  • Quit smoking as smoking increases blood pressure and heart rate.

  • Eat a balanced and healthy diet which includes plenty of vegetables, fruits, and low-fat or fat-free products.

Special Advise

  • Regular blood tests are advised while taking Dixin 0.5 mg Injection 10 x 2 ml to monitor potassium levels and kidney functioning.

  • Digoxin levels in the blood should be monitored as digoxin toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances.

Disease/Condition Glossary

Heart failure: It is a chronic condition in which the heart is unable to pump blood as effectively as it should. Heart failure may occur due to certain conditions like high blood pressure, swelling or damage of heart muscle, faulty heart valves or narrow arteries in the heart. Symptoms of heart failure include shortness of breath, tiredness, fast heartbeat and swollen legs.

Arrhythmia (irregular heartbeat): It is a condition in which the heart beats irregularly, i.e., too fast or too slow. Symptoms of irregular heartbeat include chest pain, shortness of breath, and fast or slow heartbeat. 60 to 100 beats per minute is generally considered a normal heart rate.

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Dixin 0.5 mg Injection 10 x 2 ml as it may increase drowsiness and reduce the amount of Dixin 0.5 mg Injection 10 x 2 ml in the blood leading to abnormal heart function.

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Pregnancy

Caution

Dixin 0.5 mg Injection 10 x 2 ml is a Category C pregnancy drug and is to be given to pregnant women only if it is clearly needed and prescribed by a doctor.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding. Dixin 0.5 mg Injection 10 x 2 ml is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Dixin 0.5 mg Injection 10 x 2 ml may cause dizziness, yellow or blurred vision in some people. So, drive only if you are alert after taking Dixin 0.5 mg Injection 10 x 2 ml .

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Liver

Caution

If you have any concerns regarding the use of Dixin 0.5 mg Injection 10 x 2 ml in patients with liver problems, please consult a doctor.

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Kidney

Caution

Take Dixin 0.5 mg Injection 10 x 2 ml with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Please consult the doctor. The doctor will recommend a specific dose for children based on their age.

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - DIX0001

Author Details

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FAQs

Dixin 0.5 mg Injection 10 x 2 ml is used to treat heart failure and irregular heartbeats.
Dixin 0.5 mg Injection 10 x 2 ml increases the force with which heart muscle contracts with each heartbeat and makes the heart efficient in pumping blood around the body. Thus, slows down the rate at which the heart beats and makes the heart rate normal.
Dixin 0.5 mg Injection 10 x 2 ml may cause yellow or blurred vision in some people. Therefore, be cautious before driving or using machinery.
You are recommended to avoid taking Dixin 0.5 mg Injection 10 x 2 ml if you have severe heart problems, have a history of Stokes-Adams attacks (abrupt, short-lived unconsciousness caused by a sudden change in a heartbeat), obstructive cardiomyopathy (enlargement of the heart muscle) and Wolff-Parkinson-White syndrome (extra electrical pathway causes fast heartbeat).
You are not recommended to take amiodarone with Dixin 0.5 mg Injection 10 x 2 ml as co-administration of these two medicines may increase the levels of digoxin in the blood resulting in digoxin toxicity. However, please consult a doctor before taking other medicines with Dixin 0.5 mg Injection 10 x 2 ml so that the dose may be adjusted appropriately.
You are not recommended to take more than the prescribed dose of Dixin 0.5 mg Injection 10 x 2 ml as it may cause Dixin 0.5 mg Injection 10 x 2 ml toxicity resulting in symptoms such as vomiting, nausea, loss of appetite, tiredness, dizziness or visual disturbances. However, if you experience any of these symptoms while taking Dixin 0.5 mg Injection 10 x 2 ml , please consult a doctor immediately.
Yes, Dixin 0.5 mg Injection 10 x 2 ml may cause diarrhoea as a side effect. However, it is not necessary for everyone taking Dixin 0.5 mg Injection 10 x 2 ml to experience this side effect. You are recommended to drink plenty of fluids in order to avoid dehydration. Signs of dehydration include decreased urination or dark, strong-smelling urine. Also, do not take any other medicines to treat diarrhoea without consulting your doctor. If the condition persists or worsens, please consult your doctor.

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