apollo
0
Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:19 PM IST

DINEX EC 250MG TABLET is used in the treatment of HIV. It contains didanosine, which works by inhibiting the nucleoside reverse transcriptase enzymes necessary for the virus's DNA reproduction. This inhibits viral replication and thereby prevents the further spread of infection. Common side effects of DINEX EC 250MG TABLET may include nausea, headache, stomach pain, loss of appetite, vomiting, depression, fever, tiredness, back pain, blood in urine, diarrhoea, muscle pain, dizziness, and allergic reactions.

Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Composition

DIDANOSINE-250MG

Manufacturer/Marketer

Cipla Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About DINEX EC 250MG TABLET

DINEX EC 250MG TABLET is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include fever, chills, night sweats, muscle aches, etc.

DINEX EC 250MG TABLET contains Didanosine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.

DINEX EC 250MG TABLET may cause certain side effects such as nausea, headache, stomach pain, loss of appetite, vomiting, depression, fever, tiredness, back pain, blood in urine, diarrhea, muscle pain, dizziness, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. DINEX EC 250MG TABLET should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on your health condition. Do not take more than the recommended dose.

DINEX EC 250MG TABLET should be avoided if you are allergic to it. It is advised not to take this medicine along with dapsone, loperamide, metoclopramide, nevirapine, ranitidine, rifabutin, ritonavir, stavudine, sulfamethoxazole, trimethoprim, and zidovudine as it can cause serious side effects. Hence, avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, diabetes, pancreatitis, hepatomegaly with steatosis, lactic Acidosis, peripheral nephropathy, and optic neuritis on priority. DINEX EC 250MG TABLET should be avoided in pregnant and breastfeeding women as it can cause fetal harm. DINEX EC 250MG TABLET can be used in children only if recommended by the paediatrician. If prescribed, the child should be carefully monitored for any changes. DINEX EC 250MG TABLET is used to treat the infection but does not cure or prevent it. This medicine is used in combination for the treatment of HIV infection.

Uses of DINEX EC 250MG TABLET

Treatment of HIV Infection

Medicinal Benefits

DINEX EC 250MG TABLET contains Didanosine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection. DINEX EC 250MG TABLET is used in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Directions for Use

Take DINEX EC 250MG TABLET as advised by your doctor. It should be taken without food at least 2 hours before the meal. Swallow as a whole with a glass of water. Do not chew, crush or break the medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DINEX EC 250MG TABLET

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Loss of appetite
  • Tiredness
  • Depression

Drug Warnings

DINEX EC 250MG TABLET should be avoided if you are allergic to it. It is advised not to take this medicine along with dapsone, loperamide, metoclopramide, nevirapine, ranitidine, rifabutin, ritonavir, stavudine, sulfamethoxazole, trimethoprim, and zidovudine as it can cause serious side effects. Hence, avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, diabetes, pancreatitis, hepatomegaly with steatosis, lactic Acidosis, peripheral nephropathy, and optic neuritis on priority. DINEX EC 250MG TABLET should be avoided in pregnant and breastfeeding women as it can cause fetal harm. DINEX EC 250MG TABLET is given in children only if recommended by the paediatrician. DINEX EC 250MG TABLET is used to treat the infection but does not cure or prevent it. This medicine is used in combination for the treatment of HIV infection. This medicine may cause dizziness; hence, avoid driving or operating machines while taking DINEX EC 250MG TABLET .

Drug Interactions

Drug-Drug Interactions: DINEX EC 250MG TABLET may interact with alpha-adrenergic blockers (prazosin, alfuzosin), gastrointestinal medicine (cisapride), contraceptives (ethyl estradiol, norethindrone), immunosuppressants (cyclosporin, sirolimus, tacrolimus), antibiotics (clarithromycin), anti-gout medicine (Allopurinol, probenecid), antacids, quinolone antibiotics (moxifloxacin, gatifloxacin, ofloxacin) etc.

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have cardiac problems, diabetes, pancreatitis, hepatomegaly with steatosis, lactic Acidosis, peripheral nephropathy, and optic neuritis before starting treatment with DINEX EC 250MG TABLET .

Drug-Drug Interactions Checker List

  • ALFUZOSIN
  • PRAZOSIN
  • PROBENECID
  • ALLOPURINOL
  • CYCLOSPORIN
  • TACROLIMUS
  • CLARITHROMYCIN
  • OFLOXACIN
  • MAGNESIUM HYDROXIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.  

Special Advise

  • Get an HIV test done at least every three months.
  • Regular kidney and liver function and bone mineral density tests while taking DINEX EC 250MG TABLET are advised. 
  • Regularly get blood and urine tests done while taking DINEX EC 250MG TABLET .
  • DINEX EC 250MG TABLET may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking DINEX EC 250MG TABLET should be carefully monitored throughout the treatment.

Disease/Condition Glossary

HIV Infection: Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include headache, fever, chills, joint pain, fatigue, swollen lymph nodes, sore throat, mouth nodes, muscle aches, etc. DINEX EC 250MG TABLET helps reduce the symptoms, control the infection, and also helps improve the HIV patient’s quality of life.

bannner image

Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption while taking DINEX EC 250MG TABLET to prevent unpleasant side effects.

bannner image

Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before taking DINEX EC 250MG TABLET . Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

It is unknown whether DINEX EC 250MG TABLET is excreted in human milk; because of the risk of HIV transmission and major adverse effects in nursing infants, mothers should be advised not to breastfeed if they are taking this medicine.

bannner image

Driving

Unsafe

Avoid driving vehicles as it may cause dizziness and affect your ability to drive. Hence, it is advised to drive when you are alert.

bannner image

Liver

Caution

DINEX EC 250MG TABLET should be used with caution in patients with liver impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Kidney

Caution

DINEX EC 250MG TABLET should be used with caution in patients with kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Consult your doctor

DINEX EC 250MG TABLET should be given in children only if prescribed by the paediatrician.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - DIN0012

FAQs

DINEX EC 250MG TABLET is used to treat HIV Infection.
DINEX EC 250MG TABLET contains Didanosine, which works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.
No, completing the entire treatment course prescribed by the doctor is always recommended. Sudden discontinuation of the medicine can lead to serious side effects. Your doctor will decide whether to stop the medication or not.
DINEX EC 250MG TABLET doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.
DINEX EC 250MG TABLET belongs to the class of protease inhibitors and nucleoside reverse transcriptase inhibitors (NRTIs). It is an antiretroviral medication used to treat HIV infection in children. Human Immunodeficiency Virus (HIV) is a retrovirus that attacks and damages the immune system’s cells, weakening the body’s ability to fight infections and diseases. If untreated, it can progress to Acquired Immunodeficiency Syndrome (AIDS). Common symptoms of HIV include fever, chills, night sweats, and muscle aches. The medication works by inhibiting the nucleoside reverse transcriptase enzyme, which is crucial for the virus's DNA reproduction. This inhibition prevents viral replication and halts the spread of the infection.
Yes, DINEX EC 250MG TABLET is safe if taken in the dose and duration exactly as prescribed by the doctor.
DINEX EC 250MG TABLET should be taken orally at least 30 minutes before or 2 hours after a meal. Swallow it as a whole with a glass of water. Do not chew, crush or break it.
Yes, DINEX EC 250MG TABLET is effective in treating HIV infection by inhibiting the reverse transcriptase enzyme, which is necessary for viral replication. It helps reduce the spread of the virus and improves immune function. However, its effectiveness depends on taking the medication as directed by the doctor and following the prescribed schedule.
If you forget to take a dose of DINEX EC 250MG TABLET , take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
The side effects of DINEX EC 250MG TABLET include headache, stomach pain, nausea, loss of appetite, vomiting, depression, fever, tiredness, back pain, blood in urine, diarrhoea, muscle pain, dizziness, and allergic reactions. Consult the doctor if any of these symptoms persist or worsen.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.