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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:39 PM IST
Difmol R 100mg/20mg Tablet is used to reduce pain and inflammation. It contains Diclofenac and Rabeprazole, which works by blocking the chemical effect of an enzyme called cyclo-oxygenase(COX), which produces prostaglandins (mediators of pain and inflammation) responsible for the sense of pain and inflammation (redness and swelling). Also, it prevents damage to the stomach lining caused by Diclofenac. It may cause side effects such as nausea, indigestion, flatulence, constipation, diarrhoea, and flu-like symptoms. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Difmol R 100mg/20mg Tablet

Difmol R 100mg/20mg Tablet belongs to the group of medicines called non-steroidal anti-inflammatory (NSAID). It is primarily taken to reduce pain and inflammation. Musculoskeletal pain refers to pain in the muscles, ligaments, bones, tendons, and nerves. This pain occurs in just one area of the body, like your back. You can also have it all over your body if you have a widespread situation like fibromyalgia (extreme muscle pain).

Difmol R 100mg/20mg Tablet is a combination of two drugs: Diclofenac (painkiller) and Rabeprazole (antacid). Difmol R 100mg/20mg Tablet contains diclofenac which works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) which are responsible for the sense of pain and inflammation (redness and swelling). On the other hand, Rabeprazole is a proton-pump inhibitor that prevents damage to the stomach lining caused by Diclofenac.

Take Difmol R 100mg/20mg Tablet as prescribed by your doctor. You are advised to take Difmol R 100mg/20mg Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, indigestion, flatulence, constipation, diarrhoea, and flu-like symptoms. Most of these side effects of Difmol R 100mg/20mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are allergic to Difmol R 100mg/20mg Tablet or any other medicines, please tell your doctor. To treat your condition effectually, continue taking Difmol R 100mg/20mg Tablet for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Difmol R 100mg/20mg Tablet causes drowsiness and dizziness, so drive with caution. Difmol R 100mg/20mg Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Difmol R 100mg/20mg Tablet as it could lead to increased drowsiness and dizziness. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Difmol R 100mg/20mg Tablet.

Uses of Difmol R 100mg/20mg Tablet

Treatment of Pain relief.

Medicinal Benefits

Difmol R 100mg/20mg Tablet is used to treat aches and pains, along with problems of musculoskeletal and joint pain. It helps the conditions of acute migraine headache, muscle pain, dental pain, rheumatoid arthritis, osteoarthritis, or painful menses. Difmol R 100mg/20mg Tablet is a combination drug containing diclofenac and simethicone. Difmol R 100mg/20mg Tablet contains diclofenac which works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX) which produces prostaglandins (mediators of pain and inflammation) which are responsible for the sense of pain and inflammation (redness and swelling). On the other hand, Difmol R 100mg/20mg Tablet contains Rabeprazole which is a proton-pump inhibitor that prevents harm to the stomach lining caused by Diclofenac.

Directions for Use

Swallow Difmol R 100mg/20mg Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Difmol R 100mg/20mg Tablet

  • Nausea
  • Indigestion
  • Flatulence
  • Diarrhoea
  • Flu-like symptoms
  • Constipation

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Difmol R 100mg/20mg Tablet as it may lead to increased risk of liver damage. Patients with a stomach ulcer, gastric bleeding, severe heart failure, high blood pressure, and liver or kidney disease should not take Difmol R 100mg/20mg Tablet. If you have a severe allergy to painkillers and have conditions like asthma, rhinitis (irritation and inflammation inside the nose), angioedema (swelling under the skin), or skin rashes, immediately stop taking Difmol R 100mg/20mg Tablet. Difmol R 100mg/20mg Tablet contains Rabeprazole that may cause brittle bones, so the intake of Vitamin D and calcium can be given by your doctor while using Difmol R 100mg/20mg Tablet. Besides this, it should be avoided during the last trimester of pregnancy, unless the doctor has prescribed you. If you are pregnant or breastfeeding, then do not take Difmol R 100mg/20mg Tablet without contact with the doctor. Difmol R 100mg/20mg Tablet shouldn't be given to children.

Drug Interactions

Drug-Drug Interactions: Difmol R 100mg/20mg Tablet interact with other painkillers (ketorolac, celecoxib, aspirin, ibuprofen, acetaminophen), blood thinners (Apixaban, clopidogrel, warfarin), anticancer medicines (methotrexate, busulfan), medicines for mania (lithium) antihypertensive (ramipril, aliskiren).

Drug-Food Interactions: Avoid consumption of alcohol while taking Difmol R 100mg/20mg Tablet as it might cause increased drowsiness and dizziness.

Drug-Disease Interactions: People with peptic ulcers, gastric bleeding, severe heart failure, diarrhoea, rashes, and high blood pressure should avoid intake of Difmol R 100mg/20mg Tablet as it may lead to life-threatening conditions.

Drug-Drug Interactions Checker List

  • KETOROLAC
  • CELECOXIB
  • ASPIRIN
  • IBUPROFEN
  • ACETAMINOPHEN
  • APIXABAN
  • CLOPIDOGREL
  • WARFARIN
  • METHOTREXATE
  • BUSULFAN
  • ALISKIREN
  • RAMIPRIL
  • LITHIUM

Habit Forming

No

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In the chronic conditions of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when have pain and inflammation condition. Try to sit little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Special Advise

  • Difmol R 100mg/20mg Tablet tends to cause stomach upset. Thus, it is recommended to consume Difmol R 100mg/20mg Tablet with meals to minimize gastric side effects. If you have a peptic ulcer diagnosis, Difmol R 100mg/20mg Tablet is best avoided unless prescribed by your doctor.
  • Difmol R 100mg/20mg Tablet can cause liver injury when taken in large doses. Concomitant use of alcohol is best avoided as it aggravates liver toxicity.
  • Difmol R 100mg/20mg Tablet contains Rabeprazole which may cause kidney problems in rare cases, so if you are urinating less than usual, or have blood coming in your urine, let your doctor know about this.

Disease/Condition Glossary

Musculoskeletal pain refers to pain in the muscles, ligaments, bones, tendons, and nerves. This pain occurs in just one area of the body, like your back. You can also have it all over your body if you have a widespread situation like fibromyalgia (extreme muscle pain). The pain can vary from mild to severe sufficient to affect your day-to-day life. It may start unexpectedly and be short-lived, which is known as acute pain. Pain that lasts for more than 3 to 6 months is known as chronic pain.

Rheumatoid arthritis is a chronic inflammatory disorder affecting various joints (hands and feet). In this long-term condition, our body's immune system attacks its own tissue (including joints).

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Difmol R 100mg/20mg Tablet. Alcohol intake, along with Difmol R 100mg/20mg Tablet, may cause increased drowsiness and drowsiness. It may also increase the risk of stomach bleeding. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Please consult your doctor before taking Difmol R 100mg/20mg Tablet if you are pregnant or planning to conceive

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Breast Feeding

Caution

Please consult your doctor before taking Difmol R 100mg/20mg Tablet if you are breastfeeding.

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Driving

Caution

Difmol R 100mg/20mg Tablet may cause drowsiness, dizziness, or abnormal vision. Do not drive or operate heavy machinery if you feel dizzy or drowsy.

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Liver

Caution

If u have or had a history or evidence of any liver-related diseases, please consult the doctor before taking the Difmol R 100mg/20mg Tablet.

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Kidney

Caution

If you have had a history of any kidney-related diseases, please consult the doctor before taking the Difmol R 100mg/20mg Tablet.

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Children

Unsafe

Difmol R 100mg/20mg Tablet should not be given to children below 12 years as the safety and effectiveness were not established.

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Author Details

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FAQs

Difmol R 100mg/20mg Tablet is used to reduce pain and inflammation.
Do not overdose on Difmol R 100mg/20mg Tablet or any medicine as it could lead to unpleasant side-effects. Take Difmol R 100mg/20mg Tablet only as prescribed by your doctor. Rush to your nearest doctor as early as possible if you have overdosed on Difmol R 100mg/20mg Tablet. Symptoms of overdose include nausea, vomiting, stomach pain, headache, blood in the stool.
Difmol R 100mg/20mg Tablet contains Diceclofenac and Rabeprazole. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX) which produces prostaglandins (mediators of pain and inflammation) which are responsible for redness and swelling. On the other hand, Difmol R 100mg/20mg Tablet contains Rabeprazole, a proton-pump inhibitor that prevents harm to the stomach lining caused by Diclofenac.
Difmol R 100mg/20mg Tablet may cause bladder symptoms such as frequent or painful urination and blood in the urine. If you develop these symptoms, stop taking this medication and contact your doctor immediately.
This Difmol R 100mg/20mg Tablet must be taken every day and used for serious or recurrent arthritis, as prescribed by your doctor to benefit you. Symptomatic relief may be instantaneous, within about 20-30 minutes of consumption. Typically, this drug shows its full effects within one week, but it can take up to two weeks or longer before you start to feel better in extreme situations.
Yes, Difmol R 100mg/20mg Tablet can cause dizziness in some patients. They may experience symptoms such as the feeling of fainting, weakness, or lightheadedness.

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