DI Plus 300mg/10mg Tablet is a combination medication used to treat certain parasitic infections such as Bancroft's filariasis, Eosinophilic lung, Loiasis, and River blindness. Bancroft's filariasis, also known as elephantiasis, is caused by thread-like worms that live inside the human lymphatic system. The lymphatic system of the body consists of fluid and is responsible for fighting infections. This disease spreads from person to person by mosquitoes and black flies.

DI Plus 300mg/10mg Tablet is a combination of two drugs: Cetirizine (antihistamine) and Diethylcarbamazine (anthelmintic). Cetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from allergic symptoms. Diethylcarbamazine is an anthelmintic (anti-parasitic) that works by causing paralysis of the worms by reducing muscular activity.

Take DI Plus 300mg/10mg Tablet as prescribed by your doctor. You are advised to take DI Plus 300mg/10mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, headache, dry mouth, sore throat, runny nose, nausea, vomiting, stomach upset, drowsiness, or tiredness. Most of these side effects of DI Plus 300mg/10mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to DI Plus 300mg/10mg Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, consult a doctor before using DI Plus 300mg/10mg Tablet. DI Plus 300mg/10mg Tablet is not recommended for children below 6 years of age. DI Plus 300mg/10mg Tablet should be used with caution if prescribed by a doctor. Regular eye check-ups are recommended while taking DI Plus 300mg/10mg Tablet as it may cause night blindness, tunnel vision, or loss of vision if used for a prolonged time. If you have fits, urinary retention, or serious kidney problems, inform your doctor before taking DI Plus 300mg/10mg Tablet.

DI Plus 300mg/10mg Tablet is a combination of two drugs, namely: Cetirizine and Diethylcarbamazine used to treat certain parasitic infections such as Bancroft's filariasis, Eosinophilic lung, Loiasis, and River blindness. Cetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from allergic symptoms. Diethylcarbamazine is an anthelmintic (antiparasitic) that works by causing paralysis of the worms by reducing their muscular activity.

• Dizziness
• Headache
• Dry mouth
• Sore throat
• Runny nose
• Nausea
• Vomiting
• Stomach upset
• Drowsiness
• Tiredness
•  Allergic reaction

If you are allergic to DI Plus 300mg/10mg Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, consult a doctor before using DI Plus 300mg/10mg Tablet. DI Plus 300mg/10mg Tablet is not recommended for children below 6 years of age, and for children above 6 years, DI Plus 300mg/10mg Tablet should be used with caution if prescribed by a doctor. Regular eye check-ups are recommended while taking DI Plus 300mg/10mg Tablet as it may cause night blindness, tunnel vision or loss of vision if used for a prolonged time. Your doctor may prescribe a corticosteroid along with DI Plus 300mg/10mg Tablet for certain patients with river blindness, especially those having severe symptoms to reduce the inflammation caused by the death of the worms. It is important to take corticosteroids and DI Plus 300mg/10mg Tablet exactly as prescribed by a doctor. If you have fits, urinary retention or serious kidney problems, inform your doctor before taking DI Plus 300mg/10mg Tablet.

Drug-Drug Interaction: DI Plus 300mg/10mg Tablet may interact with anti-allergic drugs (diphenhydramine), antidepressants (duloxetine), and anticonvulsants (pregabalin).

Drug-Food Interaction: DI Plus 300mg/10mg Tablet may interact with alcohol. Therefore, avoid intake of alcohol with DI Plus 300mg/10mg Tablet as it may cause increased drowsiness, dizziness, and lack of concentration.

Drug-Disease Interaction: If you have fits, urinary retention, or serious kidney problems inform your doctor before taking DI Plus 300mg/10mg Tablet.

• DIPHENHYDRAMINE
• DULOXETINE
• PREGABALIN

• Maintain a balanced diet rich in nutrients and has less refined sugars/processed foods.
• Fiber is important for bowel movement, which helps to cleanse parasites from the body so include more fiber-rich foods in the body like oats.
• Pumpkin seeds, garlic, honey, and papaya seeds are considered antiparasitic foods. So, it is best to include them in your diet.
• Sometimes doctors may recommend a grain-free, sugar-free diet while others may recommend limiting fruit intake to reduce further dietary sugars, so better talk to your nutritionist.

• If you are about to take an allergy skin test, inform your doctor that you are taking DI Plus 300mg/10mg Tablet as you may be advised to stop taking DI Plus 300mg/10mg Tablet for 3 days before the test.
• Regular blood tests are recommended while taking DI Plus 300mg/10mg Tablet to monitor blood count and liver functioning.
• Regular eye checkups to monitor  loss of vision, night blindness, or tunnel vision.

Bancroft’s Filariasis: It is also known as elephantiasis and is caused by thread-like worms that live inside the human lymphatic system. The lymphatic system of the body consists of fluid and is responsible for fighting infections. This disease spreads from person to person by mosquitoes. Common symptoms include swelling in the legs, arms, breasts, or genitals. The legs are most commonly affected while skin may also be affected, causing dry, ulcerated, thick, pitted, or darker than normal skin.

Eosinophilic lung: This is a disease related to lung problems in which white blood cells in the body get increased. White blood cells are responsible for fighting allergic reactions and certain infections. Some of the symptoms of this disease include cough, chest pain, tightness, increased mucus, rapid breathing, bloody mucus, and shortness of breath.

Loiasis: It is also called 'African eye worm' which is an infectious parasitic disease transmitted to humans by the bite of Chrysops fly species. A person infected with this disease may face itchy, non-painful swellings in their body. Sometimes, a person may see worms crawling under their skin or across the surface of the eye.

River blindness: It is caused by a parasitic worm and is transmitted through repeated bites by black flies near rivers and streams. If not treated, then it may even cause visual impairment and sometimes blindness.