DENOREG 2 TABLETS is used for the management of painful symptoms of endometriosis. Endometriosis is a painful disorder in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus. Endometriosis generally involves ovaries, pelvis lining, and fallopian tubes.
 
DENOREG 2 TABLETS contains ‘Dienogest’, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, DENOREG 2 TABLETS helps in treating pelvic pain associated with endometriosis.
 
You are advised to take DENOREG 2 TABLETS as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, DENOREG 2 TABLETS may cause side effects such as acne, headache, depression, breast discomfort, abdominal pain, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Avoid taking DENOREG 2 TABLETS if you are pregnant, planning for pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking DENOREG 2 TABLETS . DENOREG 2 TABLETS should not be given to children who have not had their first period. DENOREG 2 TABLETS may cause dizziness, so drive with caution. Avoid or limit alcohol consumption, as it could lead to increased dizziness. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

DENOREG 2 TABLETS belongs to a group of medicines called progestin indicated for the management of endometriosis. DENOREG 2 TABLETS suppresses the production of a hormone called estradiol which causes excess growth of the endometrium. Thereby, DENOREG 2 TABLETS helps in treating pelvic pain associated with endometriosis. DENOREG 2 TABLETS may also be used in menopausal hormonal therapy and heavy periods.

• Acne
• Headache
• Depression
• Breast discomfort
• Nausea
• Vomiting
• Abdominal pain

Do not take DENOREG 2 TABLETS if you are allergic to any of its components; if you have a blood clot in the lungs, heart, brain, blood vessels of legs or any part of the body, if you have/had diabetes mellitus with damaged blood vessel, severe liver damage, unexplained vaginal bleeding, and benign or malignant tumour. Talk to your doctor if you have diabetes, high blood pressure, depression, are overweight, have chloasma (yellowish-brown pigmentation on the skin), had an ectopic pregnancy (embryo develops outside the womb), or if you or anyone in your immediate family has had blood clots in lungs/legs, or heart attack, high cholesterol or stroke. Avoid taking DENOREG 2 TABLETS if you are pregnant, planning for pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking DENOREG 2 TABLETS . DENOREG 2 TABLETS should not be given to children who have not had their first period. DENOREG 2 TABLETS may cause dizziness, so drive with caution.

Drug-Drug Interactions: DENOREG 2 TABLETS may interact with anti-epileptics (phenytoin, primidone, carbamazepine, oxcarbazepine, topiramate, felbamate, phenobarbitone), anti-depressants (fluoxetine, fluvoxamine), anti-hypertensive (diltiazem, verapamil), anti-TB (rifampicin, rifabutin), anti-fungal (ketoconazole, itraconazole, fluconazole, voriconazole), antibiotics (erythromycin, clarithromycin), antacid (cimetidine), and herbal supplement used to treat depression (St. John’s wort).

Drug-Food Interactions: Avoid consumption of grapefruit while taking DENOREG 2 TABLETS . 

Drug-Disease Interactions: Inform your doctor if you have diabetes mellitus with damaged blood vessels, severe liver damage, unexplained vaginal bleeding, benign or malignant tumour.

• PHENYTOIN
• PRIMIDONE
• CARBAMAZEPINE
• OXCARBAZEPINE
• TOPIRAMATE
• FELBAMATE
• PHENOBARBITONE
• FLUOXETINE
• FLUVOXAMINE
• DILTIAZEM
• VERAMAPIL
• RIFAMPICIN
• RIFABUTIN
• KETOCONAZOLE
• ITRACONAZOLE
• FLUCONAZOLE
• VORICONAZOLE
• CLARITHROMYCIN
• ERYTHROMYCIN
• CIMETIDINE

• Include diet-fibrous foods, iron-rich foods, foods rich in essential fatty acids, and anti-oxidant rich food.

• Maintain a healthy diet and exercise regularly.

• Practice meditation and yoga. Acupuncture and massages can also be helpful.

• Avoid or limit caffeine intake.

• DENOREG 2 TABLETS might affect blood tests, inform the person doing the tests that you are taking DENOREG 2 TABLETS .

• If you are undergoing any surgery, inform the surgeon and anaesthetist that you are taking DENOREG 2 TABLETS .

Endometriosis: Endometriosis is a painful disorder in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus. Endometriosis generally occurs when the endometrial tissue grows on the ovaries, pelvis lining, and fallopian tubes. Symptoms include pelvic pain, painful periods, pain in the abdomen during and before menstruation, heavy menstrual bleeding, discomfort during bowel movements, lower back pain during menstruation, pain during sexual intercourse, and cramps 1-2 weeks around menstruation.