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Defzorix-12 Tablet 10's

Defzorix-12 Tablet 10's

Prescription drug
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Composition

DEFLAZACORT-12MG

Manufacturer/Marketer

Human Biolife India Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Defzorix-12 Tablet 10's

Defzorix-12 Tablet 10's is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy.

Defzorix-12 Tablet 10's is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Defzorix-12 Tablet 10's binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Defzorix-12 Tablet 10's class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Defzorix-12 Tablet 10's makes organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Defzorix-12 Tablet 10's is available in both oral tablet and suspension dosage forms. The tablet form of Defzorix-12 Tablet 10's can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Defzorix-12 Tablet 10's can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take Defzorix-12 Tablet 10's based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Defzorix-12 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.

Before starting Defzorix-12 Tablet 10's, please inform your doctor that you are allergic (hypersensitive) to Defzorix-12 Tablet 10's. Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors' consultation is required as Defzorix-12 Tablet 10's is not safe to use during pregnancy.

Uses of Defzorix-12 Tablet 10's

Treatment of Duchenne muscular dystrophy (DMD).

Medicinal Benefits

Defzorix-12 Tablet 10's is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Defzorix-12 Tablet 10's is a steroid that interacts with overactive immune cells, slows their activity, and decreases the damaging effects they cause in the body. 

Directions for Use

Swallow this tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Defzorix-12 Tablet 10's

Most of the side effects of Defzorix-12 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behaviour, fever, back pain, acne, nausea, restlessness, nosebleeds and stretch marks.

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Defzorix-12 Tablet 10's.  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Defzorix-12 Tablet 10's. Before taking Defzorix-12 Tablet 10's for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug Interactions

Drug-Drug interaction: Defzorix-12 Tablet 10's interact with anti-tuberculosis (anti TB) drugs like rifampicin, rifabutin, pain-relieving drugs like carbamazepine, Anti-seizure drugs like phenobarbitone, phenytoin & pyrimidine & antifungal like ketoconazole.

Drug-Food interaction: Not advised to be taken with grapefruit or its juice.

Drug-Disease interaction:  Care should be exercised when Defzorix-12 Tablet 10's is administered in patients with diabetes, cataracts, Thyroidism, blood pressure, kidney diseases, glaucoma & herpes.

 

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • RIFABUTIN
  • CARBAMAZEPINE
  • PHENOBARBITONE
  • PHENYTOIN
  • PRIMIDONE

Habit Forming

No

Diet & Lifestyle Advise

A patient needs to take extra care of hygiene & stay away from places/people believed to be a cause of infection as this drug affects a patient's immune system & thus proper care is to be taken.

 

Special Advise

  • While taking Defzorix-12 Tablet 10's and for at least 4-6 weeks before you start taking it. If you are taking Defzorix-12 Tablet 10's, so do not receive a 'live' vaccine or you could develop a serious infection.  
  • Do not eat grapefruit or drink grapefruit juice while taking this medication as grapefruit has interaction with Defzorix-12 Tablet 10's.
  • Regular eye check-ups, bone mineral test and liver function test is suggested while using Defzorix-12 Tablet 10's. 

Disease/Condition Glossary

Autoimmune disease: This is a group of disorders in which the immune system doesn't work properly due to various genetic & environmental reasons that start attacking normal cells, producing various chemicals resulting in unwanted and hazardous effects in patients. The overactive immune system leads to various symptoms that affect day-to-day life and promote diseases like arthritis and muscular weakness. The immune system can also damage the organ which has been transplanted to the patient from another person due to having different blood groups/antigens of the donor patient's organ. The immune system considers it a foreign, harmful body, leading to complications after transplanting an organ like a kidney, liver, or heart.

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Alcohol

Caution

The effect of taking both alcohol and Defzorix-12 Tablet 10's may lead to bleeding & ulcers in the stomach. Doctors' consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females.Defzorix-12 Tablet 10's crosses the placenta and doses equivalent to >40 mg prednisolone daily increase the risk of fetal and neonatal damage.

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Breast Feeding

Caution

No adverse effect is reported yet it is advised to have doctors' consultation by breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Defzorix-12 Tablet 10's can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Defzorix-12 Tablet 10's.

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Kidney

Caution

Before using Defzorix-12 Tablet 10's by a kidney patient it is recommended to have a doctors consultation. It may affect the kidney in a few cases.

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Children

Unsafe

Defzorix-12 Tablet 10's is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Defzorix-12 Tablet 10's.

Country of origin

India

Manufacturer/Marketer address

315, Industrial Area Phase 2, Panchkula, Haryana 134109
Other Info - DEF0429

Author Details

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FAQs

Defzorix-12 Tablet 10's is used to treat Duchene muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.
Not recommended in mild allergies. Defzorix-12 Tablet 10's is recommended only on consulting a doctor as Defzorix-12 Tablet 10's is a strong medicine that produces considerable side effects & thus used only in moderate to severe cases.
It is not recommended to stop by a patient himself/herself, especially by a patient undergoing organ transplantation as it may worsen the situation.
It is not recommended to be taken Defzorix-12 Tablet 10's with alcohol as it may cause stomach bleeding.
No its is not recommended to be used in seasonal allergy or mild cases. Only on doctors consultation, Defzorix-12 Tablet 10's may be used in extreme cases of seasonal allergy.
You should not use Defzorix-12 Tablet 10's if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Defzorix-12 Tablet 10's if you have a compromised immune system, eye problems or weak bones.
Yes, Defzorix-12 Tablet 10's is a steroid medication. It's a corticosteroid, also known as a glucocorticoid.
Defzorix-12 Tablet 10's is less potent than Prednisone and is usually administered proportionately in higher doses.
No, Defzorix-12 Tablet 10's is not a painkiller. It is a steroid medication.
Yes, it can be used to treat kidney stones.
Swallow it whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.
It may be unsafe for some to use. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.
Yes, it is safe to use Defzorix-12 Tablet 10's if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.
Inadequate data available on the use of this drug in pregnant women to inform a drug-related risk. So, it should be used during pregnancy only if the benefit outweighs the risk to the fetus.
Common side effects of Defzorix-12 Tablet 10's may include nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Defzorix-12 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Store in a cool and dry place away from sunlight. Please keep it away from pets and children.

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