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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:39 PM IST
Daltehep 5000 IU Injection 2 ml is used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung) and reduce the risk of getting clots in people who have undergone knee or hip replacement surgeries. Also, it helps to treat and prevent stroke risk, and heart attack in patients with atrial fibrillation (irregular heart rhythm). It contains Dalteparin which prevents the formation of blood clots by thinning the blood.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Gland Pharma Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Daltehep 5000 IU Injection 2 ml

Daltehep 5000 IU Injection 2 ml belongs to a class of drugs known as anticoagulants (blood thinner), primarily used to prevent and treat stroke risk, and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. A blood clot can occur in any part of the body, leading to a heart attack, stroke and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs and limbs.

Daltehep 5000 IU Injection 2 ml contains ‘Dalteparin’ works by inhibiting the production of clotting factors Xa and thrombin. This prevents fibrinogen's conversion (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Daltehep 5000 IU Injection 2 ml helps prevent blood clots if you have an increased risk of having a heart attack or stroke.

Take Daltehep 5000 IU Injection 2 ml as prescribed by your doctor. You are advised to take Daltehep 5000 IU Injection 2 ml for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience unusual bleeding, haematoma (blood clotting under the skin), thrombocytopenia (low number of platelets), pain and irritation at the injection site. Most of these side effects of Daltehep 5000 IU Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Daltehep 5000 IU Injection 2 ml or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Daltehep 5000 IU Injection 2 ml. Daltehep 5000 IU Injection 2 ml should be used with caution in the elderly above 65 years of age as they may be at high risk of bleeding. Daltehep 5000 IU Injection 2 ml should be given to children only if prescribed by a doctor. Extra care must be taken while brushing your teeth or shaving to prevent bleeding. If you have a stomach ulcer, kidney or liver problems, high blood pressure or bleeding problems, inform your doctor before taking Daltehep 5000 IU Injection 2 ml. Try not to stop taking this medicine of your own. Stopping a sudden intake of Daltehep 5000 IU Injection 2 ml may worsen your condition and increase your risk of cardiovascular death, heart attack and stroke.

Uses of Daltehep 5000 IU Injection 2 ml

Treatment of Blood Clot

Medicinal Benefits

Daltehep 5000 IU Injection 2 ml belongs to a class of drugs known as anticoagulants or blood thinners. Daltehep 5000 IU Injection 2 ml contains ‘Dalteparin’ used to prevent clot formation in deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain) and heart in patients with atrial fibrillation (irregular heart rhythm). Daltehep 5000 IU Injection 2 ml is primarily used to prevent and treat the risk of the acute coronary syndrome (sudden reduction or blockage of blood flow to the heart) and stroke by reducing blood clot formation. Besides this, it reduces the risk of clots in people who have undergone knee or hip replacement surgeries and abdominal surgery. Daltehep 5000 IU Injection 2 ml works by stopping the action of clotting factor Xa and thrombin (a protein that causes clotting). This prevents fibrinogen's conversion (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation.

Directions for Use

Daltehep 5000 IU Injection 2 ml will be administered by a healthcare professional, do not self-administer. If you have kidney or liver problems, please inform your doctor before taking Daltehep 5000 IU Injection 2 ml so that the dose may be adjusted accordingly.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Daltehep 5000 IU Injection 2 ml

  • Bleeding
  • Thrombocytopenia (low number of platelets)
  • Haematoma (blood clotting under the skin)
  • Pain and irritation at the site of injection
  • easy bruising or bleeding

Drug Warnings

  • If you are known to be allergic to Daltehep 5000 IU Injection 2 ml or any other medicines, please tell your doctor.

  • If you are pregnant or breastfeeding, it is advised to consult a doctor before using Daltehep 5000 IU Injection 2 ml.

  • Daltehep 5000 IU Injection 2 ml should be given to children only if prescribed by a doctor.

  • Do not use multiple-dose formulations of Daltehep 5000 IU Injection 2 ml in neonates and infants as they contain benzyl alcohol that may harm a newborn.

  • Daltehep 5000 IU Injection 2 ml should be used with caution in the elderly above 65 years of age as they may be at high risk of bleeding. 

  • If you have diabetes, high blood pressure, congestive heart failure,  blood cell disorder (low platelets or low red blood cells), bleeding in the stomach or intestines, had a stroke, kidney, liver or bleeding problems, stomach ulcer, inform your doctor before taking Daltehep 5000 IU Injection 2 ml.

  • Do not stop taking Daltehep 5000 IU Injection 2 ml of your own. Stopping a sudden intake of Daltehep 5000 IU Injection 2 ml may worsen your condition and increase your risk of cardiovascular death, heart attack and stroke. Hence, you should consult a doctor before stopping the dose of Daltehep 5000 IU Injection 2 ml.

  • You should inform the doctor that you are taking Daltehep 5000 IU Injection 2 ml before any surgery is scheduled. 

  • Daltehep 5000 IU Injection 2 ml can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural).

  • Avoid consumption of alcohol while taking Daltehep 5000 IU Injection 2 ml as it may increase the risk of stomach bleeding.

  • Extra care must be taken while brushing your teeth or shaving to prevent bleeding.

Drug Interactions

Drug-Drug Interactions: Daltehep 5000 IU Injection 2 ml may have interaction with other blood thinners (abciximab, apixaban, enoxaparin, warfarin, clopidogrel, prasugrel, rivaroxaban, dabigatran, anisindione), pain killers (ibuprofen, naproxen, diclofenac, bromfenac, celecoxib), and antihypertensive (lisinopril, losartan, aliskiren, spironolactone, eplerenone).

Drug-Food Interactions: Daltehep 5000 IU Injection 2 ml may interact with cranberry juice, grapefruit juice, noni juice, pomegranate juice, and green tea. Also, Daltehep 5000 IU Injection 2 ml may interact with St. John’s wort (herbal medicine for depression), garlic, ginkgo biloba, ginseng, echinacea, goldenseal and coenzyme Q10. Also, avoid alcohol intake as it may increase the risk of bleeding.

Drug-Disease Interactions: If you have haemophilia (blood doesn't clot normally), diabetes, high blood pressure, congestive heart failure,  blood cell disorder (low platelets or low red blood cells), bleeding in the stomach or intestines, had a stroke, kidney, liver or bleeding problems, stomach ulcer, inform your doctor before taking Daltehep 5000 IU Injection 2 ml.

Drug-Drug Interactions Checker List

  • APIXABAN
  • ENOXAPARIN
  • WARFARIN
  • CLOPIDOGREL
  • PRASUGREL
  • RIVAROXABAN
  • DABIGATRAN
  • ANISINDIONE
  • IBUPROFEN
  • NAPROXEN
  • DICLOFENAC
  • BROMFENAC
  • CELECOXIB
  • ABCIXIMAB
  • LISINOPRIL
  • LOSARTAN
  • ALISKIREN
  • SPIRONOLACTONE
  • EPLERENONE

Habit Forming

No

Diet & Lifestyle Advise

  • Do not make any changes in your diet without first talking to your doctor.
  • Avoid vitamin K-rich foods such as coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, and Brussels sprouts as they may decrease the effectiveness of Daltehep 5000 IU Injection 2 ml.
  • Avoid cranberry juice, grapefruit juice, noni juice, pomegranate juice and green tea as they may interact with Daltehep 5000 IU Injection 2 ml and lead to unwanted side effects.
  • Do the regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Avoid the consumption of alcohol as it may increase the risk of bleeding.
  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Daltehep 5000 IU Injection 2 ml.
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals and maintain a healthy diet that includes fresh fruits and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Special Advise

You should have a regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR, or international normalized ratio, to analyze your blood clotting time.

Disease/Condition Glossary

Blood clot: A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart or lungs and result in serious conditions.

Deep vein thrombosis (blood clots in legs): Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung): Pulmonary embolism is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough and shortness of breath. Stroke is a condition where a blood clot restricts blood flow to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Heart attack: A heart attack is when a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Daltehep 5000 IU Injection 2 ml as it may increase the risk of bleeding.

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Pregnancy

Caution

Daltehep 5000 IU Injection 2 ml is a Category C pregnancy drug and is given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Daltehep 5000 IU Injection 2 ml is not recommended for use in breastfeeding. If you are breastfeeding, inform your doctor before receiving Daltehep 5000 IU Injection 2 ml.

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Driving

Caution

Daltehep 5000 IU Injection 2 ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Inform your doctor if you have any pre-existing or a history of liver disease. Your doctor will weigh the benefits and potential risks before prescribing Daltehep 5000 IU Injection 2 ml. However, it is not recommended for patients with severe liver diseases.

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Kidney

Caution

Inform your doctor if you have any pre-existing or a history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Daltehep 5000 IU Injection 2 ml. However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Daltehep 5000 IU Injection 2 ml should be given to children only if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Gland Pharma Limited, 6-3-865/1/2, Greenland Apartments, Ameerpet, Hyderabad - 500016, India
Other Info - DAL0011

Author Details

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FAQs

Daltehep 5000 IU Injection 2 ml is used to prevent the risk of stroke, and heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries.
Daltehep 5000 IU Injection 2 ml contains Dalteparin, an anticoagulant (blood thinner) that inhibits the production of clotting factors Xa (a protein that causes clotting). It prevents the conversion of fibrinogen to fibrin (a protein that binds platelets together and forms a clot) and helps prevent blood clot formation.
No, you are not recommended to take clopidogrel with Daltehep 5000 IU Injection 2 ml as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
It is recommended to avoid taking grapefruit and grapefruit juice while taking Daltehep 5000 IU Injection 2 ml. It contains compounds that slow down the metabolism of Daltehep 5000 IU Injection 2 ml and increase the activity leading to bleeding.
Do not stop taking Daltehep 5000 IU Injection 2 ml without consulting your doctor to worsen the condition. Therefore, take Daltehep 5000 IU Injection 2 ml for as long as your doctor has prescribed it.
Yes, Daltehep 5000 IU Injection 2 ml may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.
Yes, Daltehep 5000 IU Injection 2 ml consists of Dalteparin is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

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Keep Refrigerated. Do not freeze.