Cugine 50mg Tablet DT belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Cugine 50mg Tablet DT also treats bipolar disorder. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. Bipolar disorder is a severe brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behavioural changes.

Cugine 50mg Tablet DT contains 'Lamotrigine' that reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, Cugine 50mg Tablet DT decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures.

You are advised to take Cugine 50mg Tablet DT for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as skin rash, headache, nausea, vomiting, dryness in the mouth, insomnia (difficulty in sleeping), sleepiness, dizziness, back pain, fatigue, abdominal pain, blurred vision, double vision, impaired coordination, nasal congestion (stuffy nose), infection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Cugine 50mg Tablet DT for as long as your doctor has prescribed. Please do not stop taking Cugine 50mg Tablet DT without consulting your doctor to avoid worsening of seizures. Do not take Cugine 50mg Tablet DT if you are pregnant or planning for pregnancy unless prescribed by the doctor, as it could lead to serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Cugine 50mg Tablet DT. Consult your doctor before taking Cugine 50mg Tablet DT if you are breastfeeding. Contact your doctor if your child gets her first period whilst on treatment with Cugine 50mg Tablet DT. Do not drive or operate machinery as Cugine 50mg Tablet DT causes drowsiness and dizziness. Avoid consuming alcohol along with Cugine 50mg Tablet DT as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies.

Cugine 50mg Tablet DT belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy and bipolar disorders. Cugine 50mg Tablet DT contains Lamotrigine, which reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Cugine 50mg Tablet DT decreases the excessive and abnormal nerve activity in the brain, thereby helping in controlling seizures. It also suppresses the release of excitatory amino acid glutamate (a chemical messenger that acts as a nerve-exciting agent) in the brain, thereby preventing episodes of fits by stabilizing nerve cell's electrical activity in the brain. Cugine 50mg Tablet DT is widely used in pediatric epilepsy because of its acceptable safety profile. Cugine 50mg Tablet DT is not associated with any psychological or physical dependence, and there is no potential for abuse.

• Skin rash
• Headache
• Nausea, vomiting
• Aggression or irritability
• Dryness in mouth
• Insomnia (difficulty in sleeping)
• Sleepiness
• Shaking or tremors
• Dizziness
• Back pain
• Fatigue
• Abdominal pain
• Blurred vision
• Double vision
• Impaired coordination
• Nasal congestion (stuffy nose)
• Infection
• Pain in your back or joints or elsewhere

If you are known to be allergic to Cugine 50mg Tablet DT or any other medicines, please tell your doctor. Please consult your doctor before taking Cugine 50mg Tablet DT if you are pregnant, planning for pregnancy, or breastfeeding. Using this medicine during pregnancy may cause harm to the unborn baby and also affect cognitive ability (reasoning, intelligence, problem-solving) later in your child's life. Cugine 50mg Tablet DT should be used with caution in children. If you have depression, liver, kidney, or pancreas problems, urea cycle disorders, inflammation of the tissue that covers the brain and spinal cord, porphyria (a disorder in the formation of red blood pigment) or thrombocytopenia (low levels of platelets), inform your doctor before taking Cugine 50mg Tablet DT. Consult your doctor immediately if you experience suicidal tendencies or mood swings. Do not stop using Cugine 50mg Tablet DT without your doctor's advice. Stopping suddenly may cause a serious, life-threatening type of seizure. Cugine 50mg Tablet DT may cause a severe or life-threatening skin rash, especially in children and in people who take a very high starting dose or those who also take valproic acid. If you have a skin rash, hives, blistering, peeling, or sores in your mouth or around your eyes, please inform your doctor immediately. Cugine 50mg Tablet DT causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Cugine 50mg Tablet DT as it could lead to increased dizziness and sleepiness.

Drug-Drug Interactions: Cugine 50mg Tablet DT may have interaction with pain killers (aspirin), anti-epileptics (oxcarbazepine, felbamate, gabapentin, levetiracetam, pregabalin, topiramate,  zonisamide, valproate, carbamazepine, phenytoin, primidone, phenobarbitone), blood thinner (warfarin), anti-HIV (zidovudine, lopinavir, ritonavir), anti-depressant (moclobemide, selegiline, linezolid, amitriptyline, sertraline, uetiapine, diazepam, olanzapine), anti-psychotic (quetiapine, olanzapine, risperidone), antibiotics (panipenem, imipenem, meropenem, rifampicin, erythromycin ), antimalarial (mefloquine, chloroquine) medicine used to treat cancer(temozolomide), calcium channel blocker (nimodipine), anaesthetic (propofol), hormone (oestrogen, levonorgestrel), antacid (cimetidine), bile-acid sequestrant (cholestyramine).

Drug-Food Interactions: Avoid alcohol consumption while taking Cugine 50mg Tablet DT as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: Cugine 50mg Tablet DT may have interactions with disease conditions such as depression, liver disease, Haemophagocytic lymphohistiocytosis (HLH) (immune disorder), Brugada syndrome (heart problem), suicidal tendency, HIV disease, thrombocytopenia (low levels of platelets).

• ASPIRIN
• OXCARBAZEPINE
• FELBAMATE
• GABAPENTIN
• LEVETIRACETAM
• PREGABALIN
• TOPIRAMATE
• ZONISAMIDE
• VALPROATE
• CARBAMAZEPINE
• PHENYTOIN
• PRIMIDONE
• PHENOBARBITONE
• WARFARIN
• ZIDOVUDINE
• LOPINAVIR
• RITONAVIR
• MOCLOBEMIDE
• SELEGILINE
• LINEZOLID
• AMITRIPTYLINE
• SERTRALINE
• UETIAPINE
• DIAZEPAM
• OLANZAPINE
• QUETIAPINE
• RISPERIDONE
• PANIPENEM
• IMIPENEM
• MEFLOQUINE
• ERYTHROMYCIN
• RIFAMPICIN
• TEMOZOLOMIDE
• ESTROGEN
• CHOLESTYRAMINE

• A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps the body utilize fat instead of glucose for energy generation.
• The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
• Rest well, and get plenty of sleep.
• Avoid smoking and alcohol consumption.
• Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
• Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
• Install an alarm or emergency device to get assistance during a seizure attack.

• Contact your doctor if your child gets her first period whilst on treatment with Cugine 50mg Tablet DT.
• If you are of childbearing age, use effective contraception without interruptions during your entire treatment with Cugine 50mg Tablet DT.
• Consult your doctor immediately if you become pregnant while taking Cugine 50mg Tablet DT.
• After taking Cugine 50mg Tablet DT, if you have thoughts of harming or killing yourself (suicidal behaviour), stop taking Cugine 50mg Tablet DT and immediately contact your doctor.

Epilepsy: It is a brain-related problem in which there is a sudden rush of electricity in the brain. This sudden, uncontrolled disturbance in nerve cell's electrical activity in the brain results in recurrent seizures (fits), sometimes leading to the unconscious state. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements, or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows.