CRESEMBA 100MG CAPSULES belongs to the class of medicines called antifungals used to treat fungal infections such as invasive aspergillosis and mucormycosis. Invasive aspergillosis is an infection caused by Aspergillus fungus. It occurs when the infection spreads from lungs to kidneys, brain, heart or skin. Mucormycosis is a rare but serious fungal infection of the skin or respiratory system that occurs in people with weakened immune systems.

CRESEMBA 100MG CAPSULES contains Isavuconazole (antifungal) that works by inhibiting the synthesis of fungal cell membranes, which are essential for their survival. Thereby, CRESEMBA 100MG CAPSULES kills or inhibits the growth of the fungus.

Take CRESEMBA 100MG CAPSULES as prescribed by your doctor. You are advised to take CRESEMBA 100MG CAPSULES for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience headache, decreased appetite, drowsiness, nausea, vomiting, stomach pain, diarrhoea or chest pain. Most of these side effects of CRESEMBA 100MG CAPSULES do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to CRESEMBA 100MG CAPSULES or any other medicines, please tell your doctor. CRESEMBA 100MG CAPSULES is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using CRESEMBA 100MG CAPSULES. Avoid breastfeeding while taking CRESEMBA 100MG CAPSULES. Drive only if you are alert after taking CRESEMBA 100MG CAPSULES as it may cause drowsiness, confusion or tiredness. Avoid alcohol consumption while taking CRESEMBA 100MG CAPSULES as it may increase the risk of liver damage.

CRESEMBA 100MG CAPSULES contains Isavuconazole, a broad-spectrum antifungal that is effective against a wide variety of microorganisms. It inhibits the synthesis of fungal cell membranes that are essential for their survival. Thereby, CRESEMBA 100MG CAPSULES kills or stops the growth of the fungus.

• Headache
• Decreased appetite
• Drowsiness
• Nausea
• Vomiting
• Stomach pain
• Diarrhoea
• Chest pain

If you are allergic to CRESEMBA 100MG CAPSULES or any other medicines, please tell your doctor. CRESEMBA 100MG CAPSULES is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using CRESEMBA 100MG CAPSULES. Avoid breastfeeding while taking CRESEMBA 100MG CAPSULES. Drive only if you are alert after taking CRESEMBA 100MG CAPSULES as it may cause drowsiness, confusion or tiredness. Avoid alcohol consumption while taking CRESEMBA 100MG CAPSULES as it may increase the risk of liver damage. If you experience severe blistering of the eyes, mouth, skin or genitals, seek immediate medical help.

Drug-Drug Interaction: CRESEMBA 100MG CAPSULES may interact with anti-HIV drug (ritonavir, efavirenz, etravirine), antibiotic (nafcillin), antitubercular drugs (rifabutin, rifampicin), anticonvulsants (carbamazepine, phenobarbital, phenytoin), antifungal (ketoconazole).

Drug-Food Interaction: CRESEMBA 100MG CAPSULES may interact with St. John’s wort (herbal medicine to treat depression).

Drug-Disease Interaction: If you have liver or heart problems, inform your doctor before taking CRESEMBA 100MG CAPSULES.

• RITONAVIR
• EFAVIRENZ
• RIFABUTIN
• RIFAMPICIN
• CARBAMAZEPINE
• PHENOBARBITAL
• PHENYTOIN
• KETOCONAZOLE
• ETRAVIRINE

• Try to avoid areas with a lot of dust like excavation or construction sites. If you can’t avoid it, wear an N95 mask while going to such places.
• Clean skin injuries with soap and water, especially if they have been exposed to dust or soil to decrease the chances of developing a skin infection.
• Bandage all wounds until they heal to prevent fungal infections.
• Wash your hands regularly and keep your hands clean to prevent the spread of germs.
• Avoid dusty activities and digging in the soil.
• Wear shoes, a long-sleeved t-shirt, long pants and a mask while doing outdoor activities such as yard work, gardening or vising wooded areas to protect from fungus commonly present in the environment.
• Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Regular blood tests are recommended while taking CRESEMBA 100MG CAPSULES to monitor liver functioning.

Invasive aspergillosis: It is an infection caused by Aspergillus fungus. It occurs when the infection spreads from the lungs to the kidneys, brain, heart or skin. It mostly occurs in people with weakened immune systems due to chemotherapy or other conditions such as cancer or AIDS. The symptoms include shortness of breath, fever, chest pain or cough (sometimes with blood).

Mucormycosis: It is a rare but serious fungal infection of the skin or respiratory system that occurs in people with weakened immune systems. If it is left untreated, it can cause death. The symptoms of respiratory infection include nasal congestion, headache, cough, fever or sinus pain. The symptoms of skin infection include redness, swelling, tenderness, blackened skin tissue, blisters or ulcers.