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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Creon 25000 Capsule is used for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. It contains Pancreatin, which help in the digestion of food. It mixes thoroughly with the food and helps in digestion as it passes through the gut. In some cases, it may cause certain common side effects such as nausea, mild stomach pain, diarrhoea, and mild skin rash. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

PANCREATIN-300MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Creon 25000 Capsule

Creon 25000 Capsule is a pancreatic enzyme supplement indicated for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. Exocrine pancreatic insufficiency occurs in people whose bodies do not make enough of their own enzymes.

Creon 25000 Capsule contains Pancreatin, which is a combination of digestive enzymes such as porcine-derived lipases, proteases, and amylases. These enzymes help in the digestion of food. Creon 25000 Capsule mixes thoroughly with the food and helps in digestion as it passes through the gut.

You are advised to take Creon 25000 Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Creon 25000 Capsule may cause certain common side-effects such as nausea, mild stomach pain, diarrhoea, and mild skin rash. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Creon 25000 Capsule if you have gout, asthma, or any disease condition. Consult your doctor before taking Creon 25000 Capsule if you are pregnant or breastfeeding. Creon 25000 Capsule may cause dizziness, so drive with caution. It is unknown whether alcohol interacts with Creon 25000 Capsule ; please consult your doctor if you have any concerns regarding this. Creon 25000 Capsule can be given to children if prescribed by the doctor; the dose depends upon the child’s age and body weight.

Uses of Creon 25000 Capsule

Treatment of Pancreatic insufficiency (pancreatin enzyme deficiency).

Medicinal Benefits

Creon 25000 Capsule is a pancreatic enzyme supplement indicated for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. Pancreatin is a combination of digestive enzymes such as porcine-derived lipases, proteases, and amylases. These enzymes help in the digestion of food. Creon 25000 Capsule mixes thoroughly with the food and helps in digestion as it passes through the gut. Creon 25000 Capsule may also be used to treat steatorrhea (oily, smelly stools due to lack of fat absorption). 

Side Effects of Creon 25000 Capsule

  • Nausea
  • Mild stomach pain 
  • Diarrhoea
  • Mild skin rash

Directions for Use

Capsule/Minimicrospheres: Swallow it as a whole with a glass of water; do not chew or crush the capsule/minimicrospheres.Granules: Mix the granules in apple/pineapple/orange juice or yoghurt; swallow the mixture directly without chewing. Do not mix pancreatin with very hot food/liquids.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Creon 25000 Capsule if you are allergic to pork (pig), cow or buffalo products. Consult your doctor if you experience stomach pain, swelling, constipation, and vomiting as patients taking Creon 25000 Capsule with cystic fibrosis may develop a rare bowel condition called fibrosing colonopathy. Inform your doctor before taking Creon 25000 Capsule if you have gout, asthma, or any disease condition. Consult your doctor before taking Creon 25000 Capsule if you are pregnant or breastfeeding. Creon 25000 Capsule may cause dizziness, so drive with caution. It is unknown whether alcohol interacts with Creon 25000 Capsule ; please consult your doctor if you have any concerns regarding this. Creon 25000 Capsule can be given to children if prescribed by the doctor; the dose depends upon the child’s age and body weight.

Therapeutic Class

ENZYMES

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat small portions of meals 3-5 times a day as larger meals make the digestive system work overtime.

  • Include diet rich in fruits and vegetables.

  • Avoid processed, deep-fried foods as they are hard to digest.

  • Maintain a balanced diet which includes proteins, carbohydrates, and fats. 

  • Stay hydrated by drinking enough water as it helps the digestive system to function smoothly.

  • Avoid highly processed foods which contain trans-fat, hydrogenated fats, and saturated fats. Instead of include foods containing monounsaturated, polyunsaturated and omega-3 fatty acids. Include olive oil, peanut oil, seeds, nuts, salmon, and tuna fish as they contain healthy fats

  • Avoid foods rich in fibre such as brown rice, barley, lentils, and peas as they might interfere with the enzyme activity.

  • Avoid or limit alcohol consumption as it can cause increased damage to the pancreas.

Habit Forming

No

How Creon 25000 Capsule Works

Creon 25000 Capsule contains Pancreatin, which is a combination of digestive enzymes such as porcine-derived lipases, proteases, and amylases. These enzymes help in the digestion of food. Creon 25000 Capsule mixes thoroughly with the food and helps in digestion as it passes through the gut.

What if I have taken an overdose of Creon 25000 Capsule

Do not take more than the prescribed dose of Creon 25000 Capsule as it may cause overdose. The symptoms of overdose include irritation or inflammation in the anal region. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Caution

It is unknown whether alcohol interacts with Creon 25000 Capsule . Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Creon 25000 Capsule belongs to pregnancy category C. Consult your doctor before taking Creon 25000 Capsule if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Creon 25000 Capsule passes into breast milk. Consult your doctor before taking Creon 25000 Capsule ; your doctor will decide whether Creon 25000 Capsule can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Creon 25000 Capsule does not affect your ability to drive. However, Creon 25000 Capsule may cause dizziness. So not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Creon 25000 Capsule if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Creon 25000 Capsule if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Creon 25000 Capsule can be given to children if prescribed by the doctor. The dose depends upon the child’s age and body weight.

Country of origin

India

Manufacturer/Marketer address

Solvate Laboratories Pvt.Ltd., C-57, IIIrd Floor, Vikas Marg, Preet Vihar, Delhi-110092
Other Info - CRE0008

Author Details

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FAQs

Creon 25000 Capsule is used to treat Pancreatic insufficiency (pancreatin enzyme deficiency).
Creon 25000 Capsule contains ‘pancreatin enzymes’ breakdown food and converts it into energy. Creon 25000 Capsule is a combination of amylase (to digest starch), protease (to digest protein) and lipase (to digest fat). Thus, together it fulfils the digestive enzymes requirements in the pancreatitis conditions (inflammation of the pancreas), pancreatic cancer, post-surgery of the pancreas, and steatorrhea (loose fatty stool due to poor fat absorption). Â
Creon 25000 Capsule might interfere with the absorption and reduce the effectiveness of folic acid and iron. To prevent this, maintain a minimum gap between both.
Diarrhoea might be a side-effect of Creon 25000 Capsule . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience watery diarrhoea or if you find blood in stools. Do not take anti-diarrhoeal medicine on your own.
Mixing Creon 25000 Capsule with non-acidic food or liquids, chewing or crushing may cause irritation in the mouth. It might also change the way Creon 25000 Capsule works in the body. Do not hold Creon 25000 Capsule or its contents in your mouth.
To treat your condition effectually continue taking Creon 25000 Capsule for as long as your doctor has prescribed it. Many patients will need to take Creon 25000 Capsule for the rest of their lives. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Creon 25000 Capsule .
Pancreatin is a pancreatic enzyme derived from the pancreatic organs of pigs used for food. Consult your doctor before taking Creon 25000 Capsule if you are allergic to the pig (pork), cow products or buffalo products.
Creon 25000 Capsule may cause side effects such as nausea, mild stomach pain, diarrhoea, and mild skin rash. If the side effects persist or worsen, consult the doctor.
Creon 25000 Capsule is safe to be used in children if prescribed by the doctor. The dose depends upon the child’s age and body weight.
Take Creon 25000 Capsule during or immediately after eating a meal or a snack and drink plenty of water.
Creon 25000 Capsule is safe to be taken if prescribed by the doctor. Do not take Creon 25000 Capsule if you are allergic to any of its ingredients, pig or pork products.
Creon 25000 Capsule should be swallowed as a whole with water. Drink plenty of liquid every day.
Include fruits, vegetables, whole grains, lean meats, poultry without skin, fish, yoghurt, cheese, and non-fat/low-fat milk. Avoid high-fat, deep-fried, and buttered foods.

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