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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 10, 2024 | 7:19 PM IST
Combactin Tablet DT is widely used medication to treat various infections caused by parasites, including strongyloidiasis (a roundworm infection) and control onchocerciasis (a worm infection that affects skin and eyes). These parasitic infections can affect the quality of life and lead to life-threatening conditions if left untreated, especially in people with weakened defence (immune) systems. It contains Ivermectin, which works by attaching to the inside of the parasite. It finally paralyzes and destroys the parasite or it prevents adult parasites from creating larvae for a while. Thus it effectively treats parasitic infections. It may cause common side effects such as headache, dizziness, muscle pain, nausea, or upset stomach.
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Prescription drug

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Composition

IVERMECTIN-12MG

Manufacturer/Marketer

Oaknet Healthcare Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Combactin Tablet DT

Combactin Tablet DT belongs to the class of anti-parasitic medicines, also known as anthelmintics. It is a widely used medication to treat various infections caused by parasites, including strongyloidiasis (a roundworm infection) and control onchocerciasis (a worm infection that affects skin and eyes). These parasitic infections can affect the quality of life and lead to life-threatening conditions if left untreated, especially in people with weakened defence (immune) systems.

Combactin Tablet DT contains ivermectin, which works by attaching to the inside of the parasite. It finally paralyzes and destroys the parasite or it prevents adult parasites from creating larvae for a while. Thus it effectively treats parasitic infections.

Take this medication as advised by your doctor. Do not alter the dose without your doctor’s advice. Common side-effects of Combactin Tablet DT are headache, dizziness, muscle pain, nausea, or upset stomach. You may also experience orthostatic hypotension (dizziness when getting up too quickly from a sitting or lying position). Most of these side effects of Combactin Tablet DT do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Combactin Tablet DT, inform your doctor if you are allergic to ivermectin or other medications. Do not consume Combactin Tablet DT if you are pregnant and breastfeeding without consulting the doctor. Tell your doctor if you are taking sedatives, anti-anxiety, or anti-epileptic drugs. Tell your doctor if you have a medical history of meningitis, human African trypanosomiasis, African sleeping sickness (an infection caused by the bite of tsetse fly in African countries), or illness that weakens the immune system, such as HIV or AIDS. Before taking the Combactin Tablet DT, inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects.

Uses of Combactin Tablet DT

Treatment of Parasitic infections [Strongyloidiasis (a threadworm infection), onchocerciasis (a worm infection).

Medicinal Benefits

Combactin Tablet DT is an anti-parasitic medication. It can kill the parasites by acting on the nervous system. It starves the worms by inducing paralysis, consequently leading them to death. In the case of strongyloidiasis, it kills the parasites present in the intestine, completely treating the infection. In the case of onchocerciasis, it can only control the infection as it can kill the developing worms but not the adult worms.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Combactin Tablet DT

  • Headache
  • Dizziness
  • Nausea
  • Muscle pain
  • Diarrhoea
  • Orthostatic hypotension
  • Head or neck pain
  • Confusion
  • Blurred vision
  • Seizures
  • Balance problems

Drug Warnings

Inform your doctor if you are allergic to Combactin Tablet DT, antiparasitic medications, or any other medications. Tell your doctor if you use any prescription, nonprescription medicines, vitamins, nutritional supplements, or other herbal products. Inform your doctor if you are previously diagnosed with meningitis, human African trypanosomiasis (an infection caused by tsetse fly), or HIV. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Inform your doctor if you ever had loa loa infection (a worm infection) or if you ever lived in West or Central Africa. Contact your doctor immediately if you experience blurred vision, seizures, trouble walking, or neck pain.

Drug Interactions

Drug-Drug interactions: Combactin Tablet DT may interact with sedatives (phenobarbital and butalbital), anti-anxiety drugs (clonazepam and lorazepam), narcotic (sodium oxybate), and antiepileptic drugs (valproic acid).

Drug-Food interactions: Limit or avoid the consumption of alcoholic beverages.

Drug-Disease interactions: Combactin Tablet DT should be used with caution in patients with meningitis, human African trypanosomiasis, and HIV.

Drug-Drug Interactions Checker List

  • PHENOBARBITAL
  • CLONAZEPAM
  • LORAZEPAM
  • VALPROIC ACID
  • BUTALBITAL
  • SODIUM OXYBATE

Habit Forming

No

Diet & Lifestyle Advise

  • It is important to have a healthy diet high in nutrients and low in refined sugars and processed foods. Fibre is precious because it keeps your intestines constantly working while washing.
  • A nutrient-rich diet is also essential to improve your immune system, as parasites are flushed out of your body.
  • Garlic, honey, pumpkin, and papaya seeds are all labelled as anti-parasitic foods to be included in your diet. 
  • Try to choose a sugar-free, grain-free diet. 
  • Suggest limiting fruit consumption to reduce dietary sugars further.
  • Avoid eating raw or undercooked meat and seafood to prevent more parasitic infections after cleansing.

Special Advise

  • To reduce dizziness upon standing, avoid standing up too quickly from a sitting or lying position. Get up slowly and rest your feet on the floor for a few minutes before standing up.

Disease/Condition Glossary

Strongyloidiasis is a threadworm infection. In this condition, a type of roundworm invades the intestine by entering into the body through the skin. It is characterized by symptoms such as abdominal pain, diarrhoea, constipation, bloating, and skin rashes. 

Onchocerciasis, also called river blindness, is a worm that affects the skin and eyes. It causes symptoms such as skin rashes, severe itching, bumps under the skin, and visual impairment.

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Alcohol

Caution

Combactin Tablet DT may interact with alcohol and increase the risk of side effects.

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Pregnancy

Caution

Combactin Tablet DT should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Combactin Tablet DT.

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Breast Feeding

Caution

Combactin Tablet DT should not be used in nursing mothers unless necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Combactin Tablet DT.

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Driving

Caution

Combactin Tablet DT may cause drowsiness and affect your ability to drive.

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Liver

Caution

Combactin Tablet DT should be used with caution in patients with liver problems. Take Combactin Tablet DT only under the supervision of a healthcare professional.

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Kidney

Safe if prescribed

Combactin Tablet DT can be used in patients with kidney problems only when prescribed by your doctor.

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Children

Caution

Combactin Tablet DT should be given to children when prescribed by a child specialist only.

Country of origin

India
Other Info - CO83292

Author Details

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FAQs

Combactin Tablet DT is a widely used medication to treat various infections caused by parasites, including strongyloidiasis (a roundworm infection) and control onchocerciasis (a worm infection that affects skin and eyes).
Combactin Tablet DT can cause fever and rash. However, you may or may not develop a fever while using Combactin Tablet DT as everybody does not experience the same side-effects.
The symptoms usually improve within two to three days after taking Combactin Tablet DT. If there is no improvement within 7 days of treatment, consult your doctor immediately.
Combactin Tablet DT can be used for treating scabies only when prescribed by a doctor.
No, it is not recommended to take Combactin Tablet DT daily. Take this medication as prescribed by your doctor.
Combactin Tablet DT should be used with caution in patients with seizures or epilepsy. Consult a doctor before using Combactin Tablet DT to avoid unwanted side-effects.
Combactin Tablet DT is used to treat parasitic infections. So, consult a doctor before using Combactin Tablet DT for any skin infection.
No, Combactin Tablet DT is not available over the counter. It can only be taken if prescribed by a doctor. Take it only under the supervision of a healthcare professional.
Take Combactin Tablet DT only as prescribed by your doctor. It should be taken on an empty stomach with the glass of water. Do not crush or chew the medicine. Avoid intake of any food 2 hours before or two hours after taking Combactin Tablet DT. In case of children less than 6 years, tablets should be crushed before swallowing.
Combactin Tablet DT is effective if it is used as advised by the doctor. Use Combactin Tablet DT for as long as it is prescribed by the doctor. Do not discontinue Combactin Tablet DT early as the symptoms may return or worsen.
Combactin Tablet DT works by binding to the muscle and nerve cells of parasites. This binding causes paralysis and death of the parasites, effectively treating the parasitic infections.
If you forget to take a dose of Combactin Tablet DT, do not worry. Take it as soon as you remember. But, if it is time for your next dose, skip the missed dose, take your regular dose. Do not take a double dose to make up for the missed dose.
Combactin Tablet DT is generally considered safe when used as directed by your doctor. It is important to follow your doctor's instructions carefully and inform them of any pre-existing conditions or other medications you are taking.
The most common side effects of Combactin Tablet DT are dizziness, neck or back pain, fast heart rate, diarrhoea and nausea. If you get effected with these side effects while taking the Combactin Tablet DT please consult your doctor.

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