Cofvex AD Syrup belongs to a class of cough and cold preparations primarily used to treat cough. Additionally, it is also used to treat allergic symptoms such as sneezing, runny nose, throat irritation, or watery eyes. Coughing (dry or productive) is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear the airways.  

Cofvex AD Syrup contains Ambroxol, Dextromethorphan hydrobromide, Phenylephrine, Chlorpheniramine maleate, and Menthol. Ambroxol works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, decreasing the need to cough. Phenylephrine works by contracting and narrowing the blood vessels. Thereby, providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Menthol produces a cooling sensation and provides relief from minor throat irritation.

Take Cofvex AD Syrup as prescribed. You are advised to take Cofvex AD Syrup for as long as your doctor has recommended it based on your medical condition. Some people may experience nausea, stomach upset, vomiting, drowsiness or headache. Most of these side effects of Cofvex AD Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Cofvex AD Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Cofvex AD Syrup. Cofvex AD Syrup should be used with caution in children. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Cofvex AD Syrup. Drink plenty of fluids while taking Cofvex AD Syrup to loosen the congestion.

Cofvex AD Syrup contains Ambroxol, Dextromethorphan hydrobromide, Phenylephrine, Chlorpheniramine maleate and Menthol. Ambroxol is a mucolytic agent that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Dextromethorphan hydrobromide is an anti-tussive agent that blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, decreasing the need to cough. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate is an anti-histamine that blocks the action of histamine, a substance responsible for causing allergic reactions. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation.

• Nausea
• Stomach upset
• Vomiting
• Drowsiness
• Headache

If you are allergic to Cofvex AD Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Cofvex AD Syrup. Cofvex AD Syrup should be used with caution in children. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Cofvex AD Syrup. Avoid using Cofvex AD Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Cofvex AD Syrup to loosen the congestion and lubricate your throat. 

Drug-Drug Interaction: Cofvex AD Syrup may interact with antibiotics (erythromycin, doxycycline, cefuroxime, amoxicillin), anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, sertraline, escitalopram), narcotic analgesics (hydrocodone, codeine), antianxiety drug (alprazolam), central nervous system stimulants (methylphenidate), antipsychotics (quetiapine), medicines used to treat irregular heartbeats  (quinidine), anticonvulsants (pregabalin), central nervous system stimulant (amphetamine).

Drug-Food Interaction: Avoid or limit the intake of chocolate and caffeine-containing foods such as cocoa beans and tea leaves with Cofvex AD Syrup as they may increase the risk of severity of side effects. Also, avoid consumption of alcohol with Cofvex AD Syrup as it may increase the risk of adverse effects such as drowsiness, dizziness, or difficulty in concentrating. 

Drug-Disease Interaction: If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, enlarged prostate, pheochromocytoma (tumour in the adrenal glands), lung, kidney, liver, heart or urinary problems, inform your doctor before taking Cofvex AD Syrup.

• ERYTHROMYCIN
• DOXYCYCLINE
• CEFUROXIME
• AMOXICILLIN
• DIPHENHYDRAMINE
• CETIRIZINE
• SERTRALINE
• ESCITALOPRAM
• HYDROCODONE
• CODEINE
• ALPRAZOLAM
• METHYLPHENIDATE
• QUETIAPINE
• QUINIDINE
• PREGABALIN
• AMPHETAMINE
• DULOXETINE

• Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods. Instead replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts, and chips with green leafy vegetables.
• Drink plenty of fluids to avoid dry throat while you have a cough. It also helps loosen mucus. 
• Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches, and pineapples.

You are recommended to inform your doctor that you are taking Cofvex AD Syrup before undergoing any medical tests or surgery.

Cough: Coughing is a body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, it indicates you may have allergies or minor infection in the respiratory tract and yellow or green mucus indicates a respiratory infection.