Cofdrain-P Syrup is used to treat symptoms of the common cold and allergies (allergic rhinitis). The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as “rhinoviruses”. The virus enters the body through the nose, mouth, or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs, or talks. Allergies are caused due to the 'allergens' that cause 'histamine' to release in the blood, thereby causing a stuffy nose, watery eyes, itching nose/throat, etc. 

Cofdrain-P Syrup is a combination medicine that contains Paracetamol, Phenylephrine hydrochloride, Chlorpheniramine maleate, Sodium citrate, and menthol. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride works by contracting and narrowing the blood vessels. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Sodium citrate works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Menthol relieves minor irritation in the throat and provides a cooling sensation.

Give Cofdrain-P Syrup to your child as advised by the doctor. Sometimes, Cofdrain-P Syrup may cause common side effects such as drowsiness, nervousness, mild headache, dizziness, insomnia (difficulty falling or staying asleep), blurred vision, nausea, vomiting, constipation, and dry mouth. Most of these side effects of Cofdrain-P Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult a doctor.

If your child is allergic to Cofdrain-P Syrup or any other medicines, please tell your doctor. For children below two years of age, please consult a doctor. Please do not give more than the prescribed dose of Cofdrain-P Syrup, as it may cause liver damage and severe adverse effects. If your child has chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before using Cofdrain-P Syrup.

Cofdrain-P Syrup contains Paracetamol, Phenylephrine hydrochloride, Chlorpheniramine maleate, Sodium citrate, and menthol used to treat symptoms of the common cold and allergies. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thus, provides relief from congestion and decreases mucus production. Chlorpheniramine maleate is an anti-allergic drug that blocks the action of histamine, a substance responsible for causing allergic reactions. Sodium citrate is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thus, helps to cough out easily. Menthol is a cooling agent that relieves minor irritation in the throat and provides a cooling sensation. Together Cofdrain-P Syrup helps relieve symptoms of a common cold like headache, fever, and allergies like stuffy nose, watery eyes, itching nose/throat, etc.

• Drowsiness
• Nervousness
• Mild headache
• Dizziness
• Insomnia (difficulty in falling or staying asleep)
• Blurred vision
• Nausea
• Vomiting
• Constipation
• Dry mouth

If your child is allergic to Cofdrain-P Syrup or any other medicines, please tell your doctor. For children below two years of age, please consult a doctor. Please do not give more than the prescribed dose of Cofdrain-P Syrup, as it may cause liver damage and severe adverse effects. If your child has chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before using Cofdrain-P Syrup.

Drug-Drug Interaction: Cofdrain-P Syrup may interact with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, escitalopram), anticonvulsants (clonazepam), antianxiety drugs (alprazolam), muscle relaxants (cyclobenzaprine), cough suppressants (dextromethorphan), bronchodilator (albuterol), sleeping agent (ramelteon), pain and fever medicines (paracetamol), pain killers (ibuprofen).

Drug-Food Interaction: Avoid foods rich in carbohydrates, pectin including jellies, cabbage, Brussels sprouts, and broccoli as Cofdrain-P Syrup may interact with these foods. Also, avoid giving Cofdrain-P Syrup with chocolate and caffeine-containing foods such as cocoa beans and tea leaves as they may increase the risk of severity of side effects. 

Drug-Disease Interaction: If your child has diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before using Cofdrain-P Syrup.

• DIPHENHYDRAMINE
• CETIRIZINE
• DULOXETINE
• ESCITALOPRAM
• CLONAZEPAM
• ALPRAZOLAM
• CYCLOBENZAPRINE
• DEXTROMETHORPHAN
• ALBUTEROL
• RAMELTEON
• PARACETAMOL
• IBUPROFEN

• Make your children wash their hands with soap and water regularly to prevent the spread of germs.
• Give plenty of foods rich in good bacteria, like yoghurt, to improve the overall health of your child.
• Let your children drink plenty of fluids to avoid dehydration.
• Ask your child to gargle with salt water for relief from a sore throat.

Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’ affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected by having 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The symptoms of the common cold include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, and stuffy or runny nose.

Allergic rhinitis: It is also known as hay fever, a type of inflammation in the nasal passage that occurs due to provoked immune system caused due to allergens in the air. Runny/stuffy nose, sneezing, watery/itchy eyes, and swelling around the eyes and inside the nasal passage are the common signs and symptoms of allergic rhinitis.