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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:37 PM IST
Clorpam Injections belongs to the class of benzodiazepines. It is used in the treatment of anxiety disorder and epilepsy/fits. This medication contains clonazepam which relieves anxiety and reduces seizures by raising the gamma-aminobutyric acid (GABA), a calming chemical mediator. It also helps relax the tense muscles. Common side effects include pain, itching, swelling or redness around the injection site, drowsiness, sedation, and tiredness.
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Prescription drug

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Composition

CLONAZEPAM-1MG

Manufacturer/Marketer

East West Pharma India Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Clorpam Injections

Clorpam Injections belongs to a group of medications called benzodiazepines, primarily used to treat status epilepticus. Status epilepticus is defined as a seizure lasting more than 5 minutes or experiencing more than one seizure within 5 minutes without returning to a normal level of consciousness between episodes.

Clorpam Injections contains clonazepam, which works by increasing levels of the calming chemical known as gamma-aminobutyric acid (GABA) in the brain, which helps to stop status epilepticus (seizures attacks).

Clorpam Injections will be administered by a healthcare professional; do not self-administer. You may experience pain, itching, swelling or redness around the site of injection, daytime drowsiness, disturbed sleep, light-headedness, or dizziness. Most of these side effects of Clorpam Injections do not require medical attention and gradually resolve over time. However, please contact your doctor if the side effects are persistent.

Do not take Clorpam Injections if you have sensitivity to clonazepam or any of the excipients present in it. Patients having a history of depression and/or suicidal tendencies should be closely monitored. If you are pregnant or breastfeeding, please tell your doctor so that your doctor will weigh the benefits and any potential risks before prescribing it to you. Clorpam Injections is a habit-forming drug; therefore, your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Uses of Clorpam Injections

Treatment of Status epilepticus

Medicinal Benefits

Clorpam Injections contains clonazepam, which works by increasing levels of the calming chemical known as gamma-aminobutyric acid (GABA) in the brain, which helps to stop status epilepticus (seizures attacks). Besides this, it may decrease the feeling of nervousness, stress, and anxiety, which leads to a state of calmness and relaxation.

Directions for Use

Clorpam Injections will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clorpam Injections

  • Pain, itching, swelling or redness around the site of injection
  • Disturbed sleep (such as vivid dreams)
  • Feeling sleepy (drowsy) in the daytime
  • Feeling light-headed,
  • Dizziness
  • Muscle weakness
  • Nystagmus (an involuntary eye movement)

Drug Warnings

Do not take Clorpam Injections if you are allergic to any of its components; if you have lung disease, muscle weakness (myasthenia gravis), sleeping disorders or difficulty sleeping (sleep apnoea), severe respiratory insufficiency, depression, suicidal tendencies, severe liver or hepatic disease, or a problem with alcohol or other prescription drugs. Inform your doctor if you have weakness, pulmonary insufficiency, kidney or liver problems. If you are pregnant or breastfeeding, please tell your doctor so that your doctor will weigh the benefits and any potential risks before prescribing it to you. Clorpam Injections is a habit-forming drug; therefore, your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Drug Interactions

Drug-Drug Interactions: Clorpam Injections may interact with antidepressant medications (sodium oxybate), antiepileptic drugs (phenytoin, phenobarbital, carbamazepine, valproate), anaesthesia medications (ketamine), hypnotics (estazolam), psychoactive drugs (nicotine, caffeine), opioid analgesic medications (alfentanil, buprenorphine, codeine, hydrocodone, hydromorphone), and muscle relaxants (tizanidine).

Drug-Food Interactions: Avoid the consumption of alcohol and caffeine.

Drug-Disease Interactions: Clorpam Injections may interact with disease conditions including acute alcohol intoxication, drug dependence, muscle weakness (myasthenia gravis), sleeping disorders or difficulty sleeping (sleep apnoea), severe respiratory insufficiency, severe liver or hepatic disease, depression and suicidal tendency.

Drug-Drug Interactions Checker List

  • SODIUM OXYBATE
  • PHENYTOIN
  • PHENOBARBITAL
  • CARBAMAZEPINE
  • VALPROATE
  • KETAMINE
  • ESTAZOLAM
  • NICOTINE
  • CAFFEINE
  • ALFENTANIL
  • BUPRENORPHINE
  • CODEINE
  • HYDROCODONE
  • HYDROMORPHONE
  • TIZANIDINE

Habit Forming

Yes

Diet & Lifestyle Advise

  • Attend therapy sessions regularly.
  • Eat a healthy diet.
  • Try to stay active and exercise regularly.
  • Take ample rest. Get enough sleep.
  • Avoid smoking, caffeine, and alcohol consumption.

Special Advise

  • Consult your doctor immediately if you have any suicidal thoughts such as killing or harming yourself.
  • Patients having a history of depression and/or suicidal tendencies should be closely monitored.

Disease/Condition Glossary

Status epilepticus: Status epilepticus is defined as a seizure lasting more than 5 minutes or experiencing more than one seizure within 5 minutes without returning to a normal level of consciousness between episodes. This is a medical emergency that may lead to permanent brain damage or death. A seizure is characterised by abnormal electrical activity in the brain, which affects both the brain and the other body parts. Seizures can be caused due to high fever, brain infections, abnormal salt or blood sugar levels, or head injuries. If you have epilepsy, you may suffer seizures on a regular basis.

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Alcohol

Unsafe

You are recommended not to consume alcohol while using Clorpam Injections to avoid unpleasant side effects like drowsiness, dizziness, or sleepiness. It may also lead to a life-threatening condition like coma if taken with excessive alcohol.

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Pregnancy

Caution

Clorpam Injections should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Clorpam Injections.

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Breast Feeding

Unsafe

Clorpam Injections may pass into breastmilk. Avoid breastfeeding while on treatment with Clorpam Injections.

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Driving

Unsafe

Clorpam Injections may cause dizziness. Avoid driving or operating heavy machinery.

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Liver

Caution

Inform your doctor if you have a history of liver diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing it.

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Kidney

Caution

Inform your doctor if you have a history of kidney diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing it.

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Children

Safe if prescribed

Special attention must be taken while using Clorpam Injections in children.

Country of origin

INDIA

Manufacturer/Marketer address

16Th Floor, Godrej Bkc, Plot C, G Block, Bandra-Kurla Complex, Bandra (East), Mumbai 400 051, India.
Other Info - CLO0872

Author Details

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FAQs

Clorpam Injections belongs to a group of medications called benzodiazepines, primarily used to treat status epilepticus.
Clorpam Injections works by increasing levels of the calming chemical known as gamma-aminobutyric acid (GABA) in the brain, which helps to stop status epilepticus (seizures attacks).
Caffeine is a stimulant that may reduce the calming effects of Clorpam Injections. So, it is advisable to avoid the intake of caffeinated beverages like coffee, tea, cola, or chocolate that contain caffeine.
Elderly patients (over 65 years) are more likely to have confusion and sleepiness or age-related health issues, which may require caution and an adjustment in the dose. Consult your doctor if you have any concerns regarding this.
If Clorpam Injections is stopped suddenly, it may cause withdrawal symptoms such as agitation, tremor, sweating, anxiety, headache, sleep disturbances, irritability, and confusion. Your doctor may lower the dose of Clorpam Injections gradually to prevent withdrawal symptoms.
Clorpam Injections should not be used in individuals in a coma or with a history of drug, alcohol, or medication abuse.

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